An article Organocatalytic Asymmetric Synthesis of Benzothiazolopyrimidines via [4+2] Cyclization of 2-Benzothiazolimines and Aldehydes WOS:000643595200031 published article about MESOIONIC XANTHINE ANALOGS; MANNICH REACTION; CYCLOADDITION; ISOTHIOUREAS; CATALYSIS; ACCESS; ACID in [Chen, Xue-Ping; Hou, Ke-Qiang; Zhou, Feng; Chan, Albert S. C.; Xiong, Xiao-Feng] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab Chiral Mol & Drug Discover, Guangzhou 510006, Peoples R China in 2021.0, Cited 41.0. Recommanded Product: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
We report the direct asymmetric synthesis of pyrimido[2,1-b]benzothiazoles using a commercially available chiral amine catalyst. A variety of 2-benzothiazolimines and aldehydes were well tolerated under the reaction conditions and generated the corresponding products in 81-99% yields with excellent diastereoselectivities and enantioselectivities (up to >20:1 dr, 99% ee). Furthermore, the products could be easily converted to other useful chiral building blocks.
Recommanded Product: 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Chen, XP; Hou, KQ; Zhou, F; Chan, ASC; Xiong, XF or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles