Application In Synthesis of Mequinol. In 2021 ORG CHEM FRONT published article about ALPHA-AMINO-ACIDS; C-H FUNCTIONALIZATION; DIELS-ALDER REACTIONS; METAL-FREE; DECARBOXYLATIVE ANNULATION; CONJUGATE ADDITION; COUPLING REACTION; MICHAEL ADDITION; VINYL ETHERS; DERIVATIVES in [Wang, Xin; Li, Gang; Li, Xiaojie; Zhu, Dunru; Shen, Ruwei] Nanjing Tech Univ, State Key Lab Mat Oriented Chem Engn, Coll Chem & Chem Engn, Nanjing 210009, Peoples R China in 2021, Cited 56. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.
The one-pot three-component reaction of p-quinone monoacetals (or p-quinol ethers), l-proline and naphthols is developed for the synthesis of N-aryl-2-arylpyrrolidines under mild conditions with high chemo- and regioselectivity. The reaction may involve multiple processes including condensation, decarboxylation and demethoxylation for the the generation of N-arylated 3,4-dihydro-2H-pyrrolium followed by controllable capture by naphthols. In the absence of a naphthol, p-quinone monoacetal coupled with l-proline to form a complex dipyrroloquinoline product.
About Mequinol, If you have any questions, you can contact Wang, X; Li, G; Li, XJ; Zhu, DR; Shen, RW or concate me.. Application In Synthesis of Mequinol
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles