Chemical Research in 123-11-5

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Becerra, D; Rojas, H; Castillo, JC or concate me.

Product Details of 123-11-5. Authors Becerra, D; Rojas, H; Castillo, JC in MDPI published article about in [Becerra, Diana; Rojas, Hugo; Castillo, Juan-Carlos] Univ Pedag & Tecnol Colombia, Escuela Ciencias Quim, Fac Ciencias, Ave Cent Norte 39-115, Tunja 150003, Colombia in 2021, Cited 27. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

We reported an efficient one-pot two-step synthesis of 3-(tert-butyl)-N-(4-methoxybenzyl)-1-methyl-1H-pyrazol-5-amine 3 in good yield by a solvent-free condensation/reduction reaction sequence starting from 3-(tert-butyl)-1-methyl-1H-pyrazol-5-amine 1 and p-methoxybenzaldehyde 2. The one-pot reductive amination proceeded by the formation in situ of the N-(5-pyrazolyl)imine 4 as key synthetic intermediate of other valuable pyrazole derivatives. This methodology is distinguished by its operational easiness, short reaction time, isolation and purification of the aldimine intermediate is not required. The structure of the synthesized N-heterocyclic amine 3 was fully characterized by FTIR-ATR, 1D and 2D NMR experiments, EIMS, and elemental analysis.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Becerra, D; Rojas, H; Castillo, JC or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles