SDS of cas: 100-51-6. In 2020.0 PROCESS BIOCHEM published article about LIPASE-CATALYZED SYNTHESIS; KINETICALLY CONTROLLED SYNTHESIS; ENHANCED BIOCATALYTIC ACTIVITY; ISOAMYL ACETATE; IMMOBILIZED LIPASE; CINNAMYL ACETATE; GERANYL CINNAMATE; PROPIONATE ESTER; EUGENYL ACETATE; NOVOZYM 435 in [de Meneses, Alessandra Cristina; Balen, Manuela; Jasper, Elaine de Andrade; Korte, Ilka; Hermes de Araujo, Pedro Henrique; Sayer, Claudia; de Oliveira, Debora] Fed Univ Santa Catarina UFSC, Dept Chem & Food Engn, BR-88040900 Florianopolis, SC, Brazil in 2020.0, Cited 77.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.
In this study, benzyl benzoate was successfully synthesized via enzymatic acylation using three immobilized enzymes as biocatalysts. Different acyl donors (benzoic acid and benzoic anhydride), operation regimes (batch, fed-batch), mixing modes (conventional mechanical stirring and ultrasound), process parameters (temperature, substrate molar ratio of acyl donor to acyl acceptor), presence or absence of solvents, enzyme amount and type were evaluated. Benzoic acid is a solid that is difficult to solubilize and, thus, was not efficient as acyl donor for the synthesis of benzyl benzoate. On the other hand, benzoic anhydride was very effective for the acylation of benzyl benzoate, and the presence of an excess of benzyl alcohol was essential to ensure the solute-solvent intermolecular attractions and good substrate solubilization, allowing the ester synthesis to be performed in the absence of organic solvents. The ultrasound was effective in increasing increase the initial reaction rate and the final conversion (88 %). However, the Lipozyme TL-IM and RM-IM supports were damaged, and the reuse was unfeasible. The batch and fed-batch approaches in conventional stirring ensured high conversions of 92 and 90 %, respectively, for batch (anhydride: alcohol 1:6) and fed-batch (1:3) using the Lipozyme TL-IM as biocatalyst. The controlled addition of the anhydride (fed-batch) allowed the reduction of alcohol molar ratio but decreased the reaction rates, and the maximum conversions were reached only after 24 h, while the batch approach had 92 % of conversion after 6 h. The yield of benzyl benzoate was high at 6 wt.% of enzyme, low temperature (50 degrees C), and simple reactor operation (batch). Results show the feasibility of the synthesis of benzyl benzoate via acylation using a green process that may be an alternative route to the chemical synthesis.
SDS of cas: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact de Meneses, AC; Balen, M; Jasper, ED; Korte, I; de Araujo, PHH; Sayer, C; de Oliveira, D or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles