Authors Nguyen, DP; Sladek, RN; Do, LH in PERGAMON-ELSEVIER SCIENCE LTD published article about TRANSFER HYDROGENATION; CARBONYL-COMPOUNDS; LEVULINIC ACID; PRIMARY AMINES; KETONES; ALDEHYDES; ALKYLATION; AMMONIA; HALIDES in [Nguyen, Dat P.; Sladek, Rudolph N.; Do, Loi H.] Univ Houston, Dept Chem, Univ Pk, Houston, TX 77004 USA in 2020.0, Cited 44.0. Safety of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4
The conversion of aldehydes and ketones to 1 degrees amines could be promoted by half-sandwich iridium complexes using ammonium formate as both the nitrogen and hydride source. To optimize this method for green chemical synthesis, we tested various carbonyl substrates in common polar solvents at physiological temperature (37 degrees C) and ambient pressure. We found that in methanol, excellent selectivity for the amine over alcohol/amide products could be achieved for a broad assortment of carbonyl-containing compounds. In aqueous media, selective reduction of carbonyls to 1 degrees amines was achieved in the absence of acids. Unfortunately, at Ir catalyst concentrations of <1 mM in water, reductive amination efficiency dropped significantly, which suggest that this catalytic methodology might be not suitable for aqueous applications where very low catalyst concentration is required (e.g., inside living cells). (C) 2020 Elsevier Ltd. All rights reserved. Safety of 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Nguyen, DP; Sladek, RN; Do, LH or concate me.
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,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles