Direct N-H/α,α,β,β-C(sp3)-H functionalization of piperidine via an azomethine ylide route: synthesis of spirooxindoles bearing 3-substituted oxindoles was written by Du, Yanlong;Yu, Aimin;Jia, Jiru;Zhang, Youquan;Meng, Xiangtai. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.HPLC of Formula: 774-47-0 This article mentions the following:
A protocol for the direct functionalization of N-H/α,α,β,β-C(sp3)-H of piperidine without any metal or external oxidants was reported. This reaction was promoted by 4-(trifluoromethyl)benzoic acid via an azomethine ylide intermediate. This was a simple method for the synthesis of spirooxindoles bearing 3-substituted oxindole moieties. In the experiment, the researchers used many compounds, for example, 5,6-Difluoroindoline-2,3-dione (cas: 774-47-0HPLC of Formula: 774-47-0).
5,6-Difluoroindoline-2,3-dione (cas: 774-47-0) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.HPLC of Formula: 774-47-0
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles