Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Product Details of 1640-39-7, Which mentioned a new discovery about 1640-39-7
It is believed that HSO3- and SO32- play important roles in several physiological processes. However, probes with two-photon absorption to detect HSO3- or SO32- in living cells are still limited. Herein, a series of novel indolium derivatives (L1-L4) with an A-pi-A? structure was designed and synthesized as ratiometric probes to detect HSO3-/SO32-in vitro. L3 and L4 display a colorimetric and ratiometric fluorescence dual response to HSO3-/SO32- with a very fast (?15 s) and high specificity, as well as low detection limits (?22 nM). Furthermore, their detection is also carried out by using a two-photon excited fluorescence method. A nucleophilic addition reaction is proposed for the sensing mechanism, which is supported by MS, 1H NMR, and density functional theory (DFT) investigations. Importantly, L3 was successfully used for detecting intrinsically generated intracellular HSO3-/SO32- in cancerous cells under one- and two-photon excited fluorescence imaging.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Product Details of 1640-39-7, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1640-39-7
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles