Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex, is researched, Molecular C4H10Cl2NiO2, CAS is 29046-78-4, about Acyl Radicals from α-Keto Acids Using a Carbonyl Photocatalyst: Photoredox-Catalyzed Synthesis of Ketones.Recommanded Product: Nickel(II) chloride ethylene glycol dimethyl ether complex.
Acyl radicals have been generated from α-keto acids RC(O)C(O)OH (R = Ph, furan-2-yl, Me, etc.) using inexpensive and com. available 2-chloro-thioxanthen-9-one as the photoredox catalyst under visible light illumination. These reactive species added to olefins R1CH=CH(R3)R2 [R1 = H, Me, Ph, 4-fluorophenyl, etc.; R2 = H, Me, C(O)OCH3, C(O)OC2H5; R3 = H, C(O)Ph, Boc, (cyclohexyloxy)carbonyl, C(O)OC2H5] or coupled with aryl halides ArX (Ar = Ph, 6-(trifluoromethyl)pyridin-2-yl, quinolin-3-yl, etc.) via a bipyridyl-stabilized Ni(II) catalyst, enabling easy access to a diverse range of ketones ArC(O)R and RC(O)CH(R1)CH(R3)R2. This reliable, atom-economical, and eco-friendly protocol is compatible with a wide range of functional groups.
After consulting a lot of data, we found that this compound(29046-78-4)Recommanded Product: Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles