Category: indole-building-block. I found the field of Chemistry very interesting. Saw the article Novel, Chiral, and Enantiopure C-2-Symmetric Thioureas Promote Asymmetric Protio-Pictet-Spengler Reactions by Anion-Binding Catalysis published in 2021.0, Reprint Addresses Piersanti, G (corresponding author), Univ Urbino Carlo Bo, Dipartimento Sci Biomol, Pzza Rinascimento 6, I-61029 Urbino, Italy.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde.
Although anion-binding processes are well-known for their crucial role in molecular recognition, they have only recently been utilized for catalysis. Herein, a new class of chiral, enantiopure C-2-symmetrical thioureas that, in combination with 4-methoxybenzoic acid, promotes the enantioselective protio-Pictet-Spengler reaction to provide unprotected tetrahydro-beta-carbolines in good yields (40-93 %) and moderate-to-high enantioselectivities (34-95 % ee) in one step from tryptamine and aldehyde derivatives is described. The formation of a chiral catalyst-anion complex was explored by H-1 NMR.
Category: indole-building-block. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles