An article Synthesis of Sulfonimidamides from Sulfenamides via an Alkoxy-amino-lambda(6)-sulfanenitrile Intermediate WOS:000483958000001 published article about NH-SULFOXIMINES; IN-VITRO; ONE-POT; COUPLING REACTIONS; ELECTROPHILIC NH; CHEMICAL SPACE; O-TRANSFER; CHEMISTRY; OPPORTUNITY; INHIBITOR in [Briggs, Edward L.; Bull, James A.] Imperial Coll London, Dept Chem, Mol Sci Res Hub, White City Campus,Wood Lane, London W12 0BZ, England; [Tota, Arianna; Colella, Marco; Degennaro, Leonardo; Luisi, Renzo] Univ Bari A Moro, Dept Pharm Drug Sci, Via E Orabona 4, I-70125 Bari, Italy in 2019.0, Cited 58.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. SDS of cas: 100-51-6
Sulfonimidamides are intriguing new motifs for medicinal and agrochemistry, and provide attractive bioisosteres for sulfonamides. However, there remain few operationally simple methods for their preparation. Here, the synthesis of NH-sulfonimidamides is achieved directly from sulfenamides, themselves readily formed in one step from amines and disulfides. A highly chemoselective and one-pot NH and O transfer is developed, mediated by PhIO in iPrOH, using ammonium carbamate as the NH source, and in the presence of 1 equivalent of acetic acid. A wide range of functional groups are tolerated under the developed reaction conditions, which also enables the functionalization of the antidepressants desipramine and fluoxetine and the preparation of an aza analogue of the drug probenecid. The reaction is shown to proceed via different and concurrent mechanistic pathways, including the formation of novel S equivalent to N sulfanenitrile species as intermediates. Several alkoxy-amino-lambda(6)-sulfanenitriles are prepared with different alcohols, and shown to be alkylating agents to a range of nucleophiles.
About Benzyl Alcohol, If you have any questions, you can contact Briggs, EL; Tota, A; Colella, M; Degennaro, L; Luisi, R; Bull, JA or concate me.. SDS of cas: 100-51-6
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles