Application In Synthesis of 1H-IndoleIn 2020 ,《The importance of indole and azaindole scaffold in the development of antitumor agents》 appeared in European Journal of Medicinal Chemistry. The author of the article were Han, Yu; Dong, Wei; Guo, Qunqun; Li, Xiufen; Huang, Longjiang. The article conveys some information:
A review. With some indoles and azaindoles being successfully developed as anticancer drugs, the design and synthesis of indole and azaindole derivatives with remarkable antitumor activity has received increasing attention and significant progress has been made. This paper reviews the recent progress in the study of tumorigenesis, mechanism of actions and structure activity relationships about anticancer indole and azindole derivatives Combining structure activity relationships and mol. targets-related knowledge, this review will help researchers design more effective, safe and cost-effective anticancer indoles and azindoles agents. In the experimental materials used by the author, we found 1H-Indole(cas: 120-72-9Application In Synthesis of 1H-Indole)
1H-Indole(cas: 120-72-9) belongs to indole. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Application In Synthesis of 1H-Indole
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles