Han, Zhi-Peng; Xu, Meng-Meng; Zhang, Rui-Ying; Xu, Xiao-Ping; Ji, Shun-Jun published an article in 2021. The article was titled 《Rh(III)-Catalyzed C(sp2)-H functionalization/cyclization cascade of N-carboxamide indole and iodonium reagents for access to indoloquinazolinone derivatives》, and you may find the article in Green Chemistry.Product Details of 399-52-0 The information in the text is summarized as follows:
A rhodium-catalyzed synthesis of indoloquinazolinones, e.g., I, from a hypervalent iodonium reagents and N-carboxamide indoles was developed. The protocol featured broad functional group tolerance, mild conditions, and excellent yields. The target products were obtained simply by filtration, without tedious column chromatog. Notably, the noble metal catalyst system could be recycled effectively at least ten times. The strategy may be amenable to industrial production5-Fluoro-1H-indole(cas: 399-52-0Product Details of 399-52-0) was used in this study.
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Fluorine-containing aromatics have been incorporated into crop-protection chemicals (herbicides, insecticides, fungicides). Liquid crystals, positron emission tomography, and imaging systems represent new areas where fluoroaromatics and fluoroheterocyclics have gained attention.Product Details of 399-52-0
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles