Quaternized chitosan as an efficient catalyst for synthesis of N-alkylthio-phthalimides was written by Hu, Zhang;Li, Sidong. And the article was included in International Journal of Chemistry (Toronto, ON, Canada) in 2010.Electric Literature of C14H9NO2S This article mentions the following:
A practical and efficient synthesis of N-alkylthio-phthalimides by the reaction of N-chlorophthalimide with thiols catalyzed by quaternized chitosan was described. The reactions were carried out in relatively mild conditions, and a variety of N-alkylthio-phthalimides were efficiently prepared with moderate to good yields. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Electric Literature of C14H9NO2S).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Electric Literature of C14H9NO2S
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles