366017-09-6, Name is Mubritinib, molecular formula is C25H23F3N4O2, COA of Formula: https://www.ambeed.com/products/366017-09-6.html, belongs to indole-building-block compound, is a common compound. In a patnet, author is Garkhedkar, Amol Milind, once mentioned the new application about 366017-09-6.
Lewis Acid Catalyzed Atom-Economic Synthesis of C2-Substituted Indoles from o-Amido Alkynols
Herein we have disclosed a Zn(OTf)(2) catalyzed synthesis of C2-alkyl substituted indole derivatives via unprecedented carbonyl group migration from o-amido alkynols. The key features of this protocol involve N,O-carbonyl group migration, broad substrate scope with varied functionality tolerance, moderate to good yields, and 100% atom economy. The crossover experiments proved that the migration is happening via an intramolecular pathway.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 366017-09-6. The above is the message from the blog manager. COA of Formula: https://www.ambeed.com/products/366017-09-6.html.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles