Jiang, Zhidong; Zhou, Jianhui; Zhu, Haoran; Liu, Hong; Zhou, Yu published their research in Organic Letters in 2021. The article was titled 《Rh(III)-Catalyzed [5+1] Annulation of Indole-enaminones with Diazo Compounds To Form Highly Functionalized Carbazoles》.Category: indole-building-block The article contains the following contents:
A novel Rh(III)-catalyzed C-H activation/annulation cascade of indole-enaminones with diazo compounds was reported to construct diversely functionalized carbazole frameworks. The most notable characteristic was that, this transformation smoothly furnished a novel [5+1] cyclization product with good to excellent yields (up to 95%), accompanied by the thorough removal of acetyl and N,N-di-Me groups of two substrates from the target products, rather than the normally expected [4+2] cyclization products. The experimental part of the paper was very detailed, including the reaction process of 5-Fluoro-1H-indole(cas: 399-52-0Category: indole-building-block)
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Fluorine-containing aromatics have been incorporated into crop-protection chemicals (herbicides, insecticides, fungicides). Liquid crystals, positron emission tomography, and imaging systems represent new areas where fluoroaromatics and fluoroheterocyclics have gained attention.Category: indole-building-block
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles