Synthesis of novel 3-acyloxy-1,3-dihydro-2H-indol-2-ones and isomeric 4-acyl-1,4-dihydro-3,1-benzoxazin-2-ones: double rearrangement of 3-hydroxyquinoline-2,4(1H,3H)-diones was written by Klasek, Antonin;Koristek, Kamil;Polis, Jiri;Kosmrlj, Janez. And the article was included in Tetrahedron in 2000.Recommanded Product: 15540-90-6 The following contents are mentioned in the article:
Substituted 3-hydroxyquinoline-2,4(1H,3H)-diones were transformed into 3-acyloxy-1,3-dihydro-2H-indol-2-ones and isomeric 4-acyl-1,4-dihydro-3,1-benzoxazin-2-ones. The influence of the substituents and the reaction conditions on the course of the reaction was studied. In the proposed mechanism, a double rearrangement takes place; α-ketol rearrangement, leading to a α-hydroxy β-diketone intermediate, is followed by a rearrangement to the isomeric α-ketol esters. This study involved multiple reactions and reactants, such as 4,7-Dimethylindoline-2,3-dione (cas: 15540-90-6Recommanded Product: 15540-90-6).
4,7-Dimethylindoline-2,3-dione (cas: 15540-90-6) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Recommanded Product: 15540-90-6
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles