Preparation of 2-[(2-cyanoethyl)thio]-1H-isoindole-1,3(2H)-dione and related sulfur-transfer agents was written by Klose, Jana;Reese, Colin B.;Song, Quanial. And the article was included in Tetrahedron in 1997.Formula: C14H9NO2S This article mentions the following:
The title compound (I, R = CH2CH2CN) and a morpholine analog (II) are both conveniently prepared in good yield from 2-cyanoethyl disulfide, which itself is readily prepared in one step from S-(2-cyanoethyl)isothiouronium chloride. In the same way, di-Me and di-Ph disulfides are converted to I (R = Me, Ph, resp.), also in good yields. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Formula: C14H9NO2S).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Formula: C14H9NO2S
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles