Lu, Ming-Zhu; Ding, Xin; Shao, Changdong; Hu, Zhengsong; Luo, Haiqing; Zhi, Sanjun; Hu, Huayou; Kan, Yuhe; Loh, Teck-Peng published the artcile< Direct Hiyama Cross-Coupling of (Hetero)arylsilanes with C(sp2)-H Bonds Enabled by Cobalt Catalysis>, Quality Control of 93247-78-0, the main research area is pyrimidyl indole arylsilane cobalt catalyst Hiyama cross coupling arylation; arylsilane pyrimidyl pyrrole cobalt catalyst Hiyama cross coupling arylation.
A chelation-assisted C-H arylation of various indoles with sterically and electronically diverse (hetero)arylsilanes enabled by cost-effective Cp*-free cobalt catalysis was reported. Key to the success of this strategy was the judicious choice of copper(II) fluoride as a bifunctional sliane activator and catalyst reoxidant. This methodol. features a broad substrate scope and good functional group compatibility. The synthetic versatility of this protocol was highlighted by the gram-scale synthesis and late-stage diversification of biol. active mols.
Organic Letters published new progress about Aryl silanes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 93247-78-0 belongs to class indole-building-block, and the molecular formula is C10H9NO2, Quality Control of 93247-78-0.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles