Catalyst-Free Chemoselective Reduction of Nitroarenes Using Thiourea as a Hydrogen Source was written by Lv, Mei-fang;Lu, Guo-ping;Cai, Chun. And the article was included in Asian Journal of Organic Chemistry in 2015.COA of Formula: C8H6N2O2 This article mentions the following:
A newly developed protocol for the reduction of nitroarenes using thiourea as the hydrogen source was described. The method was simple, inexpensive and easily applicable to the preparation of a variety of substituted anilines with high yields and selectivity. In contrast to traditional hydrogenation methods, this chem. does not required a catalyst, elaborated work-up procedures, or the use of high-pressure equipment. In the experiment, the researchers used many compounds, for example, 6-Nitro-1H-indole (cas: 4769-96-4COA of Formula: C8H6N2O2).
6-Nitro-1H-indole (cas: 4769-96-4) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.COA of Formula: C8H6N2O2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles