Product Details of 100-51-6. Recently I am researching about CROSS-COUPLING REACTIONS; DIARYLMETHYL CARBONATES; DECARBOXYLATIVE BENZYLATION; ASYMMETRIC BENZYLATION; DIMETHYL MALONATE; GRIGNARD-REAGENTS; ALPHA-BENZYLATION; ARYLBORONIC ACIDS; PALLADIUM; ALKYLATION, Saw an article supported by the Research Grant of Institute of Natural Sciences at Nihon University; Japan Society for the Promotion of ScienceMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [17K05794]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Tsuji, H; Hashimoto, K; Kawatsura, M. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol
The nickel-catalyzed benzylic substitution of benzyl alcohol derivatives with a soft carbon nucleophile is extremely rare compared to that with a hard carbon nucleophile. We have achieved the nickel-catalyzed benzylic substitution of benzyl esters with malonates as a soft carbon nucleophile. Primary and secondary benzyl 2,3,4,5,6-penta-fluorobenzoates as well as a wide variety of malonate derivatives were well tolerated in the nickel-catalyzed reaction, providing the corresponding alkylation products in 46-86% yields (34 examples). Additionally, we propose a possible reaction mechanism that would undergo via the eta(1)- and eta(3)-benzylnickel intermediates.
Product Details of 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Tsuji, H; Hashimoto, K; Kawatsura, M or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles