Recommanded Product: 100-51-6. Recently I am researching about ANDROGEN RECEPTOR; APOPTOSIS; MECHANISMS; DIAGNOSIS; CELLS, Saw an article supported by the Shanghai Science and Technology Council [18ZR1411200]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772043]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Chen, HQ; Xing, YJ; Xie, J; Xie, JQ; Xing, D; Tang, J; Yang, F; Yi, ZF; Qiu, WW. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol
A series of novel 3-nitro-4-chromanones were synthesized and their in vitro cytotoxicity was evaluated on castration-resistant prostate cancer cell (CRPC) lines using the sulforhodamine B (SRB) assay. The amide derivatives showed more potent antitumor activity than their corresponding ester derivatives. Most of the tested compounds showed less toxicity towards human fibroblasts (HAF) compared with the tumor cell lines. The optimal compound 36 possessed much more potent antiproliferative activity than the positive compound cisplatin. The colony formation, cell cycle distribution, apoptosis, transwell migration and wound healing assays of 36 were performed on CRPC cell lines.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles