Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Dealkylation of N-pyridylethyl-2-arylbenzimidazoles by aluminum chloride.Category: indole-building-block.
Dealkylation of I (R = 2- or 4-pyridyl, R1 = Ph, 2- or 4-pyridyl), prepared by alkylation of the corresponding benzimidazole with 2- or 4-vinylpyridine, with AlCl3 in CCl4 5 h at 150° gave II (R1 as above) in 30-40% yields when R = 2-pyridyl and 85-90% yields when R = 4-pyridyl.
If you want to learn more about this compound(2-(Pyridin-4-yl)-1H-benzo[d]imidazole)Category: indole-building-block, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(2208-59-5).
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles