Recommanded Product: m-Methoxyphenol. In 2020 TETRAHEDRON LETT published article about NONCOVALENT INHIBITION; INDUCED HETEROARYLATION; PRIVILEGED SCAFFOLD; 20S PROTEASOME; CANCER; QUINOLINE; IDENTIFICATION; QUINAZOLINES; ALLOSTERY; TMC-95A in [Boualia, Imen; Debache, Abdelmadjid; Boulcina, Raouf] Univ Freres Mentouri Constantine, Lab Synthese Mol Interets Biol, Constantine 25000, Algeria; [Boualia, Imen; Roisnel, Thierry; Berree, Fabienne; Vidal, Joelle; Carboni, Bertrand] Univ Rennes, ISCR, CNRS, UMR 6226, F-35000 Rennes, France; [Boulcina, Raouf] Univ Mostefa Benboulaid Batna 2, Dept Sci & Tech, Fac Technol, Batna 05000, Algeria in 2020, Cited 45. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.
A new series of 3-(quinazol-2-yl)-quinolines was synthesized by SNAr reaction from easily prepared 4-chloro-2-(2-chloroquinolin-3-yl)quinazolines and a range of phenols and thiophenol as nucleophiles. The AlCl3-mediated CC bond formation was also successfully exploited to introduce aryl and hereroaryl substituents on one or both heterocyclic units. These procedures afford efficient syntheses of polysubstituted 3-(quinazol-2-yl)-quinolines in few steps and high yields. Some of these polysubstituted 3-(quinazol-2-yl)-quinolines inhibit the human 20S proteasome. (C) 2020 Elsevier Ltd. All rights reserved.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles