Computed Properties of C8H7NIn 2021 ,《Indole derivatives, microbiome and graft versus host disease》 appeared in Current Opinion in Immunology. The author of the article were Qayed, Muna; Michonneau, David; Socie, Gerard; Waller, Edmund K.. The article conveys some information:
A review. Graft vs host disease is a life-threatening complication following allogeneic hematopoietic stem cell transplantation driven by donor T cells reacting against disparate host antigens. Immune homeostasis within the gut plays a major role in the graft vs host response. Gut microbiota and its metabolites impact gut integrity, inflammation and immune activation within the gut. This review will focus on the role of indoles, a product of microbiota metabolism, on gut homeostasis and our current understanding on how that modulates graft vs host disease. In addition to this study using 1H-Indole, there are many other studies that have used 1H-Indole(cas: 120-72-9Computed Properties of C8H7N) was used in this study.
1H-Indole(cas: 120-72-9) belongs to indole. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C8H7N
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles