Anticancer and antioxidant activities of 2-aminobenzoic acid (2-oxo-1,2-dihydro-indol-3-ylidene) hydrazides was written by Sammaiah, G.;Narsaiah, N.;Krishnaveni, J.;Dayakar, G.;Sarangapani, M.. And the article was included in International Journal of Chemical Sciences in 2008.Safety of 7-Nitroindoline-2,3-dione This article mentions the following:
In this communication, the anticancer and antioxidant activities of some new 2-aminobenzoic acid (2-oxo-1,2-dihydro-indol-3-ylidene) hydrazides are presented. The new compounds were prepared by the condensation of indole-2,3-diones with 2-aminobenzoic acid hydrazide. All the compounds were evaluated for anticancer activity (against HeLa cell lines, IMR-32 cell lines) and antioxidant activity. Some of the compounds exhibited moderate anticancer activity against the cell lines employed and promising antioxidant activity. In the experiment, the researchers used many compounds, for example, 7-Nitroindoline-2,3-dione (cas: 112656-95-8Safety of 7-Nitroindoline-2,3-dione).
7-Nitroindoline-2,3-dione (cas: 112656-95-8) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Safety of 7-Nitroindoline-2,3-dione
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles