Authors El-Emary, TI; Abdel-Mohsen, SA; Mohamed, SA in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about CALCIUM-CHANNEL BLOCKERS; DIHYDROPYRIMIDINE in [El-Emary, Talaat, I; Abdel-Mohsen, Shawkat A.; Mohamed, Shereen A.] Assiut Univ, Fac Sci, Dept Chem, Assiut 71516, Egypt in 2021.0, Cited 27.0. Recommanded Product: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
The synthesis of 5-acetyl-6-methyl-4-(1,3-diphenyl-1H-pyrazol-4-yl)-3,4-dihydropyrmidin-2(1H)-thione was achieved by one-pot three-component synthesis using CaCl2 in refluxing EtOH. The starting compound was utilized to synthesize a new series of 5-pyrazolyl; isoxazolyl; pyrimidinyl derivatives via the synthesized chalcone. Also, fused isoxazolo [5,4-d]pyrimidine and pyrazolo[3,4-d]pyrimidine were obtained by the treatment of 5-acetyl derivative with hydroxyl amine and/ or hydrazine hydrate. Also, the thiosemicarbazide derivative was prepared and utilized to synthesize other new thiazole derivatives. The structures of all compounds have been established on the basis of their analytical and spectral data. All compounds was also evaluated for their antibacterial and antifungal activity against various strains of bacteria and fungi. Also, the anti-inflammatory activity of some of synthesized compounds was evaluated using the carrageenan induced paw oedema test in rats using indomethacin as the reference drug.
Recommanded Product: 123-11-5. Welcome to talk about 123-11-5, If you have any questions, you can contact El-Emary, TI; Abdel-Mohsen, SA; Mohamed, SA or send Email.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles