Name: 4-Methoxybenzaldehyde. In 2021 ARKIVOC published article about CATALYTIC ASYMMETRIC-SYNTHESIS; BETA-LACTONE DIMER; DISUBSTITUTED KETENES; ONE-POT; DERIVATIVES; DIMERIZATION; DIMETHYLKETENE; AMINES in [Ibrahim, Ahmad A.; Harzmann, Gero D.; Nalla, Divya; Elledge, Beth; Van Raaphorst, Max] Oakland Univ, Dept Chem, 2200 N Squirrel Rd, Rochester, MI 48309 USA; [Kerrigan, Nessan J.] Dublin City Univ, Sch Chem Sci, Dublin 9, Ireland in 2021, Cited 36. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.
An investigation of the reaction of heteroatom nucleophiles with ketene dimers, with an emphasis on a discussion of diastereoselectivity where applicable, is described. During this study we focused on the reaction of nitrogen-centred nucleophiles (Weinreb amine, lithiated Weinreb amide, and an amino acid derivative), and oxygen-centred nucleophiles (alkoxides). Simple Weinreb amide derivatives of ketene heterodimers were formed in moderate to excellent yield (up to 89%) and excellent retention of chirality (ee up to 91%), albeit with poor diastereoselectivity. The 2-pyridone-catalysed amine ring-opening was also applied to the asymmetric synthesis of a cinnabaramide A intermediate. Finally, the use of amide and alkoxide ring-opening nucleophiles enabled the development of a sequential one-pot reaction with benzaldehyde to afford delta-lactones in moderate yields (up to 47%) but with good diastereoselectivity (dr up to 24:1). [GRAPHICS]
About 4-Methoxybenzaldehyde, If you have any questions, you can contact Ibrahim, AA; Harzmann, GD; Nalla, D; Elledge, B; Van Raaphorst, M; Kerrigan, NJ or concate me.. Name: 4-Methoxybenzaldehyde
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles