So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Moon, Yonghoon; Lee, Wooseok; Hong, Sungwoo researched the compound: 2-Phenylpyridine( cas:1008-89-5 ).Name: 2-Phenylpyridine.They published the article 《Visible-Light-Enabled Ortho-Selective Aminopyridylation of Alkenes with N-Aminopyridinium Ylides》 about this compound( cas:1008-89-5 ) in Journal of the American Chemical Society. Keywords: blue LED ortho selective aminopyridylation alkene aminopyridinium ylide. We’ll tell you more about this compound (cas:1008-89-5).
By utilizing an underexplored reactivity mode of N-aminopyridinium ylides, we developed the visible-light-induced ortho-selective aminopyridylation of alkenes via radical-mediated 1,3-dipolar cycloaddition The photocatalyzed single-electron oxidation of N-aminopyridinium ylides generates the corresponding radical cations that enable previously inaccessible 1,3-cycloaddition with a broader range of alkene substrates. The resulting cycloaddition adducts rapidly undergo subsequent homolytic cleavage of the N-N bond, conferring a substantial thermodn. driving force to yield various β-aminoethylpyridines. Remarkably, amino and pyridyl groups can be installed into both activated and unactivated alkenes with modular control of ortho-selectivity and 1,2-syn-diastereoselectivity under metal-free and mild conditions. Combined exptl. and computational studies are conducted to clarify the detailed reaction mechanism and the origins of site selectivity and diastereoselectivity.
There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=CC=C2)=NC=CC=C1)Name: 2-Phenylpyridine, and with the development of science, more effects of this compound(1008-89-5) can be discovered.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles