Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Zhang, Hao-Lin, once mentioned the application of 127-69-5, Name is Sulfisoxazole, molecular formula is C11H13N3O3S, molecular weight is 267.3042, MDL number is MFCD00003150, category is indole-building-block. Now introduce a scientific discovery about this category, Safety of Sulfisoxazole.
An efficient synthesis of thieno[2,3-b]indoles via a one-pot three-component reaction was well established. By using inexpensive and commercial available indoles and a, a-unsaturated carboxylic acids in the presence of elemental sulfur, various functional groups were achieved in moderate to good yields. (C) 2018 Elsevier Ltd. All rights reserved.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles