Tag: 202.2524

Reusable Bronsted Acidic Ionic Liquid Efficiently Catalyzed N-Formylation and N-Acylation of Amines was written by Li, Chun;Wang, Mengna;Lu, Xunhua;Zhang, Ling;Jiang, Jian;Zhang, Lin. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Reference of 1016-47-3 This article mentions the following:

We disclose efficient and green N-formylation and N-acylation methodologies of various amines with carboxylic acids for the synthesis of versatile amides in the presence of Bronsted acidic ionic liquid Furthermore, the N-formylation and N-acylation with DMF and DMA have also been achieved in the same catalytic system. Notably, the catalyst in this catalytic solvent-free protocol could be easily recycled for up to five consecutive cycles with slight loss of activity. Novel, efficient, and green N-formylation and N-acylation catalyzed by reusable and metal-free Bronsted acidic ionic liquids without cocatalyst and solvent are presented. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Reference of 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Reference of 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Palladium Metallaphotoredox-Catalyzed 2-Arylation of Indole Derivatives was written by Wang, Xinmou;Xun, Xiwei;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin. And the article was included in Organic Letters in 2022.SDS of cas: 1016-47-3 This article mentions the following:

Herein, a two-step method for C(sp2)-H/C(sp2)-H cross-coupling reactions was reported to synthesize 2-arylindole derivatives I [R¹ = H, 4-Me, 5-I, etc.; Ar = 4-t-BuC₆H₄, 4-PhOC₆H₄, 3-Br-4-MeOC₆H₃, etc.] by combining palladium catalysis and photocatalysis. This mild, dual-catalysis method showed good functional group tolerance and a wide substrate scope and could be used for late-stage functionalization of oligopeptides, drugs, and natural products. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3SDS of cas: 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.SDS of cas: 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

A PKS I gene-based screening approach for the discovery of a new polyketide from Penicillium citrinum Salicorn 46 was written by Wang, Xiaomin;Wang, Hui;Liu, Tianxing;Xin, Zhihong. And the article was included in Applied Microbiology and Biotechnology in 2014.Application of 1016-47-3 This article mentions the following:

Salicorn 46, an endophytic fungus isolated from Salicornia herbacea Torr., was identified as Penicillium citrinum based on its internal transcribed spacer and ribosomal large-subunit DNA sequences using a type I polyketide synthase (PKS I) gene screening approach. A new polyketide, penicitriketo (I), and seven known compounds, including ergone (2), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,9,22-trien-3-ol (3), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,22-dien-3-ol (4), stigmasta-7,22-diene-3β,5α,6α-triol (5), 3β,5α-dihydroxy-(22E,24R)-ergosta-7,22-dien-6β-yl oleate (6), N_b-acetyltryptamine (7), and 2-(1-oxo-2-hydroxyethyl) furan (8), were isolated from the culture of Salicorn 46, and their chem. structures were elucidated by spectroscopic anal. Antioxidant experiments revealed that compound I possessed moderate DPPH radical scavenging activity with an IC₅₀ value of 85.33 ± 1.61 μM. Antimicrobial assays revealed that compound 2 exhibited broad-spectrum antimicrobial activity against Candida albicans, Clostridium perfringens, Mycobacterium smegmatis, and Mycobacterium phlei with minimal inhibitory concentration (MIC) values of 25.5, 25.5, 18.5, and 51.0 μM, resp. Compound 3 displayed potent antimicrobial activities against C. perfringens and Micrococcus tetragenus with a MIC value of 23.5 μM. Compounds 5 and 6 showed high levels of selectivity toward Bacillus subtilis and M. phlei with MIC values of 22.5 and 14.4 μM, resp. The results of this study highlight the use of PCR-based techniques for the screening of new polyketides from endophytic fungi containing PKS I genes. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Application of 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Application of 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Isolation, identification and antimicrobial activity of secondary metabolites from a soil-derived Streptomyces from arid habitats of Qinghai was written by Yu, Zhi-yin;Yu, Ming-ming;Luo, Jian-ying;Su, Can;Xue, Quan-hong;Huang, Sheng-xiong;Sun, Yun;Ma, Ya-tuan. And the article was included in Tianran Chanwu Yanjiu Yu Kaifa in 2015.Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide This article mentions the following:

Five compounds, including N-acetyltyramine(1), N-acetyltryptamine(2), pyrrole-2-carboxamide(3), inthomycin C(4) and inthomycin B(5), were isolated from the fermentation broth of Streptomyces pactum KIB-HL8, and their structures were elucidated by anal. of NMR and MS data. In addition, compound 4 moderately inhibited growth of Staphylococcus aureus. Compounds 1 and 2 showed significant antifungal activity against Botrytis cinerea. Compound 3 displayed inhibitory activity against Alternaria solani. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

A PKS I gene-based screening approach for the discovery of a new polyketide from Penicillium citrinum Salicorn 46 was written by Wang, Xiaomin;Wang, Hui;Liu, Tianxing;Xin, Zhihong. And the article was included in Applied Microbiology and Biotechnology in 2014.Application of 1016-47-3 This article mentions the following:

Salicorn 46, an endophytic fungus isolated from Salicornia herbacea Torr., was identified as Penicillium citrinum based on its internal transcribed spacer and ribosomal large-subunit DNA sequences using a type I polyketide synthase (PKS I) gene screening approach. A new polyketide, penicitriketo (I), and seven known compounds, including ergone (2), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,9,22-trien-3-ol (3), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,22-dien-3-ol (4), stigmasta-7,22-diene-3β,5α,6α-triol (5), 3β,5α-dihydroxy-(22E,24R)-ergosta-7,22-dien-6β-yl oleate (6), N_b-acetyltryptamine (7), and 2-(1-oxo-2-hydroxyethyl) furan (8), were isolated from the culture of Salicorn 46, and their chem. structures were elucidated by spectroscopic anal. Antioxidant experiments revealed that compound I possessed moderate DPPH radical scavenging activity with an IC₅₀ value of 85.33 ± 1.61 μM. Antimicrobial assays revealed that compound 2 exhibited broad-spectrum antimicrobial activity against Candida albicans, Clostridium perfringens, Mycobacterium smegmatis, and Mycobacterium phlei with minimal inhibitory concentration (MIC) values of 25.5, 25.5, 18.5, and 51.0 μM, resp. Compound 3 displayed potent antimicrobial activities against C. perfringens and Micrococcus tetragenus with a MIC value of 23.5 μM. Compounds 5 and 6 showed high levels of selectivity toward Bacillus subtilis and M. phlei with MIC values of 22.5 and 14.4 μM, resp. The results of this study highlight the use of PCR-based techniques for the screening of new polyketides from endophytic fungi containing PKS I genes. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Application of 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Application of 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Isolation, identification and antimicrobial activity of secondary metabolites from a soil-derived Streptomyces from arid habitats of Qinghai was written by Yu, Zhi-yin;Yu, Ming-ming;Luo, Jian-ying;Su, Can;Xue, Quan-hong;Huang, Sheng-xiong;Sun, Yun;Ma, Ya-tuan. And the article was included in Tianran Chanwu Yanjiu Yu Kaifa in 2015.Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide This article mentions the following:

Five compounds, including N-acetyltyramine(1), N-acetyltryptamine(2), pyrrole-2-carboxamide(3), inthomycin C(4) and inthomycin B(5), were isolated from the fermentation broth of Streptomyces pactum KIB-HL8, and their structures were elucidated by anal. of NMR and MS data. In addition, compound 4 moderately inhibited growth of Staphylococcus aureus. Compounds 1 and 2 showed significant antifungal activity against Botrytis cinerea. Compound 3 displayed inhibitory activity against Alternaria solani. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Reusable Bronsted Acidic Ionic Liquid Efficiently Catalyzed N-Formylation and N-Acylation of Amines was written by Li, Chun;Wang, Mengna;Lu, Xunhua;Zhang, Ling;Jiang, Jian;Zhang, Lin. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Reference of 1016-47-3 This article mentions the following:

We disclose efficient and green N-formylation and N-acylation methodologies of various amines with carboxylic acids for the synthesis of versatile amides in the presence of Bronsted acidic ionic liquid Furthermore, the N-formylation and N-acylation with DMF and DMA have also been achieved in the same catalytic system. Notably, the catalyst in this catalytic solvent-free protocol could be easily recycled for up to five consecutive cycles with slight loss of activity. Novel, efficient, and green N-formylation and N-acylation catalyzed by reusable and metal-free Bronsted acidic ionic liquids without cocatalyst and solvent are presented. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Reference of 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Reference of 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Palladium Metallaphotoredox-Catalyzed 2-Arylation of Indole Derivatives was written by Wang, Xinmou;Xun, Xiwei;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin. And the article was included in Organic Letters in 2022.SDS of cas: 1016-47-3 This article mentions the following:

Herein, a two-step method for C(sp2)-H/C(sp2)-H cross-coupling reactions was reported to synthesize 2-arylindole derivatives I [R¹ = H, 4-Me, 5-I, etc.; Ar = 4-t-BuC₆H₄, 4-PhOC₆H₄, 3-Br-4-MeOC₆H₃, etc.] by combining palladium catalysis and photocatalysis. This mild, dual-catalysis method showed good functional group tolerance and a wide substrate scope and could be used for late-stage functionalization of oligopeptides, drugs, and natural products. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3SDS of cas: 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.SDS of cas: 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Isolation, identification and antimicrobial activity of secondary metabolites from a soil-derived Streptomyces from arid habitats of Qinghai was written by Yu, Zhi-yin;Yu, Ming-ming;Luo, Jian-ying;Su, Can;Xue, Quan-hong;Huang, Sheng-xiong;Sun, Yun;Ma, Ya-tuan. And the article was included in Tianran Chanwu Yanjiu Yu Kaifa in 2015.Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide This article mentions the following:

Five compounds, including N-acetyltyramine(1), N-acetyltryptamine(2), pyrrole-2-carboxamide(3), inthomycin C(4) and inthomycin B(5), were isolated from the fermentation broth of Streptomyces pactum KIB-HL8, and their structures were elucidated by anal. of NMR and MS data. In addition, compound 4 moderately inhibited growth of Staphylococcus aureus. Compounds 1 and 2 showed significant antifungal activity against Botrytis cinerea. Compound 3 displayed inhibitory activity against Alternaria solani. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Recommanded Product: N-(2-(1H-Indol-3-yl)ethyl)acetamide

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

A PKS I gene-based screening approach for the discovery of a new polyketide from Penicillium citrinum Salicorn 46 was written by Wang, Xiaomin;Wang, Hui;Liu, Tianxing;Xin, Zhihong. And the article was included in Applied Microbiology and Biotechnology in 2014.Application of 1016-47-3 This article mentions the following:

Salicorn 46, an endophytic fungus isolated from Salicornia herbacea Torr., was identified as Penicillium citrinum based on its internal transcribed spacer and ribosomal large-subunit DNA sequences using a type I polyketide synthase (PKS I) gene screening approach. A new polyketide, penicitriketo (I), and seven known compounds, including ergone (2), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,9,22-trien-3-ol (3), (3β,5α,8α,22E)-5,8-epidioxyergosta-6,22-dien-3-ol (4), stigmasta-7,22-diene-3β,5α,6α-triol (5), 3β,5α-dihydroxy-(22E,24R)-ergosta-7,22-dien-6β-yl oleate (6), N_b-acetyltryptamine (7), and 2-(1-oxo-2-hydroxyethyl) furan (8), were isolated from the culture of Salicorn 46, and their chem. structures were elucidated by spectroscopic anal. Antioxidant experiments revealed that compound I possessed moderate DPPH radical scavenging activity with an IC₅₀ value of 85.33 ± 1.61 μM. Antimicrobial assays revealed that compound 2 exhibited broad-spectrum antimicrobial activity against Candida albicans, Clostridium perfringens, Mycobacterium smegmatis, and Mycobacterium phlei with minimal inhibitory concentration (MIC) values of 25.5, 25.5, 18.5, and 51.0 μM, resp. Compound 3 displayed potent antimicrobial activities against C. perfringens and Micrococcus tetragenus with a MIC value of 23.5 μM. Compounds 5 and 6 showed high levels of selectivity toward Bacillus subtilis and M. phlei with MIC values of 22.5 and 14.4 μM, resp. The results of this study highlight the use of PCR-based techniques for the screening of new polyketides from endophytic fungi containing PKS I genes. In the experiment, the researchers used many compounds, for example, N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3Application of 1016-47-3).

N-(2-(1H-Indol-3-yl)ethyl)acetamide (cas: 1016-47-3) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Application of 1016-47-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles