Tag: M.W=100-150

Formula: C8H8O2. In 2019.0 J ORG CHEM published article about C-C; ARYLATION; COPPER; HYDRAZONES; MILD in [Onodera, Shunsuke; Kochi, Takuya; Kakiuchi, Fumitoshi] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, 3-14-1 Hiyoshi, Yokohama, Kanagawa 2238522, Japan in 2019.0, Cited 40.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A method for the synthesis of N-arylpyrazoles by palladium-catalyzed coupling of aryl triflates with pyrazole derivatives is described. Using tBuBrettPhos as a ligand, the palladium-catalyzed C-N coupling of a variety of aryl triflates including ortho-substituted ones with pyrazole derivatives proceeded efficiently to give N-arylpyrazole products in high yields. 3-Trimethylsilylpyrazole was found to be an excellent pyrazole substrate for the coupling, and the corresponding product, 1-aryl-3-trimethylsilylpyrazole, also served as a great template for the syntheses of N-arylpyrazole derivatives, as demonstrated by regioselective halogenation at the 3-, 4-, and 5- positions of the pyrazole ring.

Formula: C8H8O2. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Onodera, S; Kochi, T; Kakiuchi, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2020 CATAL SCI TECHNOL published article about FACILE SYNTHESIS; REACTANTS ACTIVATION; NO ADSORPTION; DOPED G-C3N4; EFFICIENT; NANOSHEETS; ZIRCONIA; REACTIVITY; VACANCIES; MECHANISM in [Wang, Jiadong; Chen, Ruimin; Yuan, Chaowei; Dong, Fan; Sun, Yanjuan] Chongqing Technol & Business Univ, Coll Environm & Resources, Chongqing Key Lab Catalysis & New Environm Mat, Chongqing 400067, Peoples R China; [Wang, Jiadong; Cui, Wen; He, Ye; Yuan, Chaowei; Sheng, Jianping; Li, Jieyuan; Dong, Fan; Sun, Yanjuan] Univ Elect Sci & Technol China, Inst Fundamental & Frontier Sci, Res Ctr Environm Sci & Technol, Chengdu 611731, Peoples R China; [Cui, Wen] Southwest Petr Univ, Sch Mat Sci & Engn, Ctr New Energy Mat & Thchnol, Chengdu 610500, Peoples R China; [Zhan, Yuxin] Chongqing Univ, Coll Mat Sci & Engn, Chongqing 400044, Peoples R China in 2020, Cited 60. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. SDS of cas: 123-11-5

Graphitic carbon nitride (g-C3N4, CN for short) is a compelling visible-light responsive photocatalyst. However, its photocatalytic efficiency is low due to the random carrier transfer in planes and insufficient redox potential. Herein, we build oxygen functional group modified sodium-doped carbon nitride (OH/Na co-functionalized carbon nitride) to promote directional transfer of charge carriers for acceleration of separation and enhance redox potential for efficient oxidation of NO in air. Specifically, the function of sodium atoms could control the directional transfer of random carriers from the intralayer to the oxygen functional group-modified surface for the purpose of effectively reducing photogenerated electron-hole recombination. Meanwhile, the modification by oxygen-containing functional groups could adjust the band structure of CN, thereby increasing the oxidation-reduction potential of NO in the photocatalyst. The transformation pathways and reaction mechanism of photocatalytic NO oxidation on CN and OH/Na co-functionalized carbon nitride have also been explicated by ESR spectroscopy and in situ DRIFTS and compared. This work provides a new method for simultaneously controlling the random transfer of carriers and adjusting the energy band structure of CN to optimize its photocatalytic efficiency. It is also possible to extend this strategy to improve the performance of other 2D layered catalysts for photocatalytic oxidation.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Wang, JD; Cui, W; Chen, RM; He, Y; Yuan, CW; Sheng, JP; Li, JY; Zhan, YX; Dong, F; Sun, YJ or concate me.. SDS of cas: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H8O. In 2019 ACS OMEGA published article about COPPER-CATALYZED HYDROXYLATION; STAPHYLOCOCCUS-AUREUS; PHYSICOCHEMICAL PROPERTIES; ANTIBACTERIAL COMPOUNDS; MOLECULAR COMPLEXITY; EFFICIENT SYNTHESIS; DISCOVERY; ANTIBIOTICS; LEAD; RESISTANCE in [Lim, Andrew S. T.; Gilbert, Ian H.] Univ Dundee, Div Biol Chem & Drug Discovery, Wellcome Ctr Antiinfect Res, Drug Discovery Unit, Dundee DD1 5EH, Scotland; [Vincent, Isabel M.; Barrett, Michael P.] Univ Glasgow, Wolfson Wohl Canc Res Ctr, Glasgow Poly, Garscube Campus, Bearsden G61 1QH, Scotland; [Barrett, Michael P.] Univ Glasgow, Inst Infect Immun & Inflammat, Wellcome Ctr Mol Parasitol, Glasgow G12 8TA, Lanark, Scotland in 2019, Cited 52. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to design compounds with optimal physicochemical properties to permeate the bacterial cell envelope. We described an approach of combining and integrating whole cell screening and metabolomics into early antibacterial drug discovery using a library of small polar compounds. Whole cell screening of a diverse library of small polar compounds against Staphylococcus aureus gave compound 2. Hit expansion was carried out to determine structure-activity relationships. A selection of compounds from this series, together with other screened active compounds, was subjected to an initial metabolomics study to provide a metabolic fingerprint of the mode of action. It was found that compound 2 and its analogues have a different mode of action from some of the known antibacterial compounds tested. This early study highlighted the potential of whole cell screening and metabolomics in early antibacterial drug discovery. Future works will require improving potency and performing orthogonal studies to confirm the modes of action.

Computed Properties of C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Lim, AST; Vincent, IM; Barrett, MP; Gilbert, IH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Saka, ET; Kahriman, N in ELSEVIER SCIENCE SA published article about THIN-FILMS; COBALT PHTHALOCYANINE; ZINC PHTHALOCYANINE; CYCLOHEXENE OXIDATION; SELECTIVE OXIDATION; SUBSTITUTED CO(II); FE(II); 2,6-DI-TERT-BUTYLPHENOL; AUTOXIDATION; DEGRADATION in [Saka, Ece Tugba; Kahriman, Nuran] Karadeniz Tech Univ, Fac Sci, Dept Chem, TR-61080 Trabzon, Turkey in 2019.0, Cited 43.0. Application In Synthesis of m-Methoxyphenol. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

Phenols from various man-made activities pose threats to public health and aquatic ecosystems. A number of technologies (e.g., adsorption, oxidation, and biological methods) have been proposed and tested to remove phenolic compounds from different sources. Among these technologies, oxidation process is considered one of the most efficient tools for abating phenolic compounds because of low cost, easy scalability, and ecofriendly production. In this work, we aim to synthesize and characterize potential catalysts (Co(II) and Cu(II) phthalocyanines 6 and 7) for phenolic compounds oxidation. Different parameters influenced the oxidation process were determined and phenolic compounds oxidize to the less harmful products with high conversion and yield in the presence of Co(II) and Cu(II) phthalocyanine catalysts. (c) 2019 Elsevier B.V. All rights reserved.

About m-Methoxyphenol, If you have any questions, you can contact Saka, ET; Kahriman, N or concate me.. Application In Synthesis of m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Selective Ketone Formations via Cobalt-Catalyzed beta-Alkylation of Secondary Alcohols with Primary Alcohols WOS:000487577200049 published article about BORROWING-HYDROGEN; ALPHA-ALKYLATION; AROMATIC-AMINES; N-ALKYLATION; EFFICIENT CATALYSTS; PINCER COMPLEXES; METHYLATION; IMINES; DEHYDROGENATION; METALS in [Pandey, Bedraj; Xu, Shi; Ding, Keying] Middle Tennessee State Univ, Dept Chem, Murfreesboro, TN 37132 USA; [Ding, Keying] Middle Tennessee State Univ, Mol Biosci Program, Murfreesboro, TN 37132 USA in 2019.0, Cited 74.0. COA of Formula: C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

A homogeneous cobalt-catalyzed beta-alkylation of secondary alcohols with primary alcohols to selectively synthesize ketones via acceptorless dehydrogenative coupling is reported for the first time. Notably, this transformation is environmentally benign and atom economical with water and hydrogen gas as the only byproducts.

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Pandey, B; Xu, S; Ding, KY or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of Benzyl Alcohol. I found the field of Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model published in 2019.0, Reprint Addresses Ahn, JH (corresponding author), Gwangju Inst Sci & Technol, Dept Chem, Gwangju 61005, South Korea.; Choi, SY (corresponding author), Chonnam Natl Univ, Dept Biomed Sci, Med Sch, Gwangju, South Korea.; Shin, MG (corresponding author), Chonnam Natl Univ, Dept Lab Med, Med Sch, Gwangju, South Korea.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol.

A new series of 1,3-diketone, heterocyclic and alpha, beta-unsaturated derivatives were synthesized and evaluated for their AhR antagonist activity using zebrafish and mammalian cells. Compounds 1b, 2c, 3b and 5b showed significant AhR antagonist activity in a transgenic zebrafish model. Among them, compound 3b, and 5b were found to have excellent AhR antagonist activity with IC50 of 3.36 nM and 8.3 nM in a luciferase reporter gene assay. In stem cell proliferation assay, compound 5b elicited marked HSC expansion.

Application In Synthesis of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Jeong, J; Kim, KH; Kim, DY; Chandrasekaran, G; Kim, M; Pagire, SH; Dighe, M; Choi, EY; Bak, SM; Kim, EY; Shin, MG; Choi, SY; Ahn, JH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans WOS:000542724200063 published article about ONE-POT SYNTHESIS; MARINE SPONGE; BIOLOGICAL-ACTIVITY; EFFICIENT SYNTHESIS; TERMINAL ALKYNES; O-ALKYNYLPHENOLS; FACILE SYNTHESIS; ALKENYL PHENOLS; C-C; MICROWAVE in [Aggarwal, Sakshi; Srinivas, Dasari; Sreenivasulu, Chinnabattigalla; Satyanarayana, Gedu] Indian Inst Technol, Dept Chem, Hyderabad 502285, Telangana, India in 2020.0, Cited 81.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Application In Synthesis of m-Methoxyphenol

Recent research has been focused on the transition metal-catalyzed reactions. Herein we have developed nickel-catalyzed synthesis of 3-aryl benzofurans fromortho-alkenyl phenolsviaintramolecular dehydrogenative coupling. Notably, simple O(2)gas served as an oxidant, without using any sacrificial hydrogen acceptor. The strategy enabled the synthesis of 3-aryl benzofurans in good to excellent yields.

Application In Synthesis of m-Methoxyphenol. About m-Methoxyphenol, If you have any questions, you can contact Aggarwal, S; Srinivas, D; Sreenivasulu, C; Satyanarayana, G or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis of treprostinil: key Claisen rearrangement and catalytic Pauson-Khand reactions in continuous flow WOS:000494856500010 published article about PROCESS WINDOWS; CHEMISTRY; REACTORS; LIQUID; SAFE in [Garcia-Lacuna, Jorge; Dominguez, Gema; Perez-Castells, Javier] Univ San Pablo CEU, Fac Farm, Dept Quim & Bioquim, Madrid 28668, Spain; [Blanco-Urgoiti, Jaime] CSFlowChem SL, C Boadilla Camino 3, Madrid 28050, Spain in 2019.0, Cited 51.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4. Name: 3-Hydroxybenzaldehyde

A new synthesis of treprostinil is described using a plug flow reactor in two of the key steps. First, a Claisen rearrangement reaction is described in scaled flow at multigram amounts. Yields and selectivity of this step are sharply improved compared to those from previous syntheses. Second, the key Pauson-Khand reaction in flow is described under catalytic conditions with 5 mol% of cobalt carbonyl and only 3 equiv. of CO. Scaling up of this reaction safely ensures a good yield of an advanced intermediate which is transformed into treprostinil in three steps. Other improvements are the introduction of the carboxymethyl chain into the phenol from the beginning to reduce the protection-deprotection steps. The synthesis is completed in 14% global yield after 12 linear steps from (S)-epichlorhydrin.

Name: 3-Hydroxybenzaldehyde. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Garcia-Lacuna, J; Dominguez, G; Blanco-Urgoiti, J; Perez-Castells, J or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 150-19-6. In 2020.0 ANGEW CHEM INT EDIT published article about SHAPE-PERSISTENT MACROCYCLES; BOTTOM-UP SYNTHESIS; NANOHOOPS; ARYLENE in [Wang, Jinyi; Chen, Muqing; Lu, Dapeng; Huang, Qiang; Jia, Hongxing; Cui, Shengsheng; Yang, Shangfeng; Du, Pingwu] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Mat Energy Convers, Dept Mat Sci & Engn,iChEM Collaborat Innovat Ctr, Hefei 230026, Anhui, Peoples R China; [Zhuang, Guilin] Zhejiang Univ Technol, Coll Chem Engn, 18 Chaowang Rd, Hangzhou 310032, Zhejiang, Peoples R China; [Li, Zhe; Shao, Xiang] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Dept Chem Phys, Hefei 230026, Anhui, Peoples R China in 2020.0, Cited 68.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6.

Carbon nanotubes (CNTs) have unusual physical properties that are valuable for nanotechnology and electronics, but the chemical synthesis of chirality- and diameter-specific CNTs and pi-conjugated CNT segments is still a great challenge. Reported here are the selective syntheses, isolations, characterizations, and photophysical properties of two novel chiral conjugated macrocycles ([4]cyclo-2,6-anthracene; [4]CAn(2,6)), as (-)/(+)-(12,4) carbon nanotube segments. These conjugated macrocyclic molecules were obtained using a bottom-up assembly approach and subsequent reductive elimination reaction. The hoop-shaped molecules can be directly viewed by a STM technique. In addition, chiral enantiomers with (-)/(+) helicity of the [4]CAn(2,6) were successfully isolated by HPLC. The new tubular CNT segments exhibit large absorption and photoluminescence redshifts compared to the monomer unit. The carbon enantiomers are also observed to show strong circularly polarized luminescence (g(lum)approximate to 0.1). The results reported here expand the scope of materials design for bottom-up synthesis of chiral macrocycles and enrich existing knowledge of their optoelectronic properties.

About m-Methoxyphenol, If you have any questions, you can contact Wang, JY; Zhuang, GL; Chen, MQ; Lu, DP; Li, Z; Huang, Q; Jia, HX; Cui, SS; Shao, X; Yang, SF; Du, PW or concate me.. SDS of cas: 150-19-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. Yu, M; Wu, CL; Zhou, L; Zhu, L; Yao, XQ in [Yu, Min] Nanjing Xiaozhuang Univ, Sch Environm Sci, Nanjing 211171, Peoples R China; [Yu, Min; Wu, Chaolong; Zhou, Li; Yao, Xiaoquan] Nanjing Univ Aeronaut & Astronaut, Coll Mat Sci & Technol, Nanjing 210016, Peoples R China; [Zhu, Li] Nanjing Med Univ, Sch Pharm, Nanjing 210029, Peoples R China published Aerobic Oxidation of Aldehydes to Carboxylic Acids Catalyzed by Recyclable Ag/C3N4 Catalyst in 2021, Cited 59. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

The oxidation of aldehydes is an efficient methodology for the synthesis of carboxylic acids. Herein we hope to report a simple, efficient and recyclable protocol for aerobic oxidation of aldehydes to carboxylic acid by using C3N4 supported silver nanoparticles (Ag/C3N4) as a catalyst in aqueous solution under mild conditions. Under standard conditions, the corresponding carboxylic acids can be obtained in good to excellent yields. In addition, Ag/C3N4 is convenient for recovery and could be reused three times with satisfactory yields.

HPLC of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Yu, M; Wu, CL; Zhou, L; Zhu, L; Yao, XQ or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles