Tag: M.W=100-150

Category: indole-building-block. In 2019.0 FOOD CHEM published article about THEOBROMA-CACAO L.; FREE AMINO-ACIDS; TOF-MS; GEOGRAPHICAL ORIGIN; VOLATILE COMPOUNDS; NOSESPACE ANALYSIS; CLASSIFICATION; CHOCOLATE; TIME; FOOD in [Acierno, Valentina; Fasciani, Giorgia; Kiani, Sajad; van Ruth, Saskia] RIKILT Wageningen Univ & Res, POB 230, NL-6700 AE Wageningen, Netherlands; [Acierno, Valentina; van Ruth, Saskia] Wageningen Univ & Res, Food Qual & Design Grp, POB 17, NL-6700 AA Wageningen, Netherlands; [Fasciani, Giorgia; Caligiani, Augusta] Univ Parma, Dept Food Sci, Parco Area Sci 17-A, I-43124 Parma, Italy; [Kiani, Sajad] Tarbiat Modares Univ, Biosysterns Engn Dept, Tehran, Iran in 2019.0, Cited 40.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

The wide range of geographical cocoa production areas and the increasing consumption trend towards single origin products induced the necessity to verify and certify cocoa beans origin for quality assurance purposes. In this study cocoa beans of various origins were examined by machine olfaction and machine vision techniques. Fifty-nine fermented and dried Forastero cocoa beans from 23 different geographical origins (Africa, Americas, Southeast Asia) were investigated using Proton Transfer Reaction-Quadrupole interface-Time of Flight-Mass Spectrometry and Hyperspectral Imaging to elucidate the geographical information in the beans. The volatile and spectral fingerprints showed the same tendency in clustering samples from Africa separate from those from the Americas. High variability was observed for the Southeast Asian samples, which is most likely related to differences in fermentation. Machine olfaction and machine vision characterization provided a similar degree of separation but are complementary rapid techniques, which may be further developed for use in practical settings.

About Benzyl Alcohol, If you have any questions, you can contact Acierno, V; Fasciani, G; Kiani, S; Caligiani, A; van Ruth, S or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2021 J ANAL APPL PYROL published article about STEAM GASIFICATION; BIOMASS PYROLYSIS; INHERENT ALKALI; CANCER-RISK; FLY-ASH; BIO-OIL; PAHS; BEHAVIORS; EVOLUTION; GAS in [Xiao, Lingfeng; Hu, Song; Han, Hengda; Ren, Qiangqiang; He, Limo; Jiang, Long; Su, Sheng; Wang, Yi; Xiang, Jun] Huazhong Univ Sci & Technol, Sch Energy & Power Engn, State Key Lab Coal Combust, Wuhan 430074, Peoples R China; [Hu, Song; Su, Sheng; Xiang, Jun] Huazhong Univ Sci & Technol, China EU Inst Clean & Renewable Energy, Wuhan 430074, Peoples R China; [Jiang, Long] Huazhong Univ Sci & Technol, Sch Energy & Power Engn, Dept New Energy Sci & Engn, Wuhan 430074, Peoples R China in 2021, Cited 38. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. COA of Formula: C7H8O2

OPAHs and SPAHs are highly genotoxic and would largely be formed during the thermal conversion of lignin. Herein, the distribution of OPAHs and SPAHs in lignin pyrolytic tar at different temperatures is elaborated with ESI (-) FT-ICR MS and GC-MS, and the formation routes of two typical OPAH and SPAH are deeply explored via DFT. It is found that most of oxygen-containing compounds convert to phenols and their homologues such as guaiacol (a typical precursor of OPAHs) with the temperature increased. The tar prepared at high temperature contains disulfide, thiophene and thiophene homologues, which are typical precursors of SPAHs. FT-ICR-MS strongly suggests that molecular mass of OPAHs and SPAHs compounds mainly concentrates between 200 Da and 400 Da with carbon atom number from 5 to 25 and DBE from 4 to 15. Higher temperature significantly promotes deoxygenation reaction since weighted average carbon atom number and DBE of molecules increase 28.4 % and 12.9 %, while the corresponding weighted average oxygen atom number decreases from 7.21 to 5.96 with temperature rising from 500 degrees C to 900 degrees C. Incorporating with DFT calculation, the pathways of OPAHs and SPAHs during lignin pyrolysis at high temperature are concluded: Guaiacol converts to 1-methoxynaphthalene via 4 methylation reactions, and butene firstly generates thiophene and then converts to methyl-benzothiophene. Among the reactions above, benzene ring and thiophene ring generation steps possess the highest energy barriers (436.74 kJ/mol and 446.33 kJ/mol), further illustrating higher temperature promotes the formation of OPAHs and SPAHs.

COA of Formula: C7H8O2. About m-Methoxyphenol, If you have any questions, you can contact Xiao, LF; Hu, S; Han, HD; Ren, QQ; He, LM; Jiang, L; Su, S; Wang, Y; Xiang, J or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O. In 2020.0 FOOD MICROBIOL published article about NON-SACCHAROMYCES YEASTS; BOTRYTIS-CINEREA; BIOCONTROL ABILITY; CEREVISIAE; FERMENTATION; MECHANISM; VIRULENCE; GRAPES; FUNGI in [Lemos, Wilson J. F., Jr.; Binati, Renato L.; Felis, Giovanna E.; Slaghenaufi, Davide; Ugliano, Maurizio; Torriani, Sandra] Univ Verona, Dept Biotechnol, I-37134 Verona, Italy in 2020.0, Cited 47.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Gray mold caused by Botrytis cinerea is a fungal disease that can determine significant economic losses of apple during the storage phase. An alternative to reduce the use of traditional synthetic fungicides is to employ the yeast Starmerella bacillaris as biological control agent (BCA), also with positive effect on apple juice fermentation for the production of cider. Thus, we aimed to evaluate the safety of 16 S. bacillaris strains and their ability to control B. cinerea. In addition, the fermentation performances in apple juice and the volatile organic compounds (VOCs) profile were assessed, both in single-strain and in sequential fermentations with Saccharomyces cerevisiae. The in vitro assays showed that all S. bacillaris strains can be considered safe from the analyzed virulence factors, and were able to significantly constrain the growth of B. cinerea, reducing mycelial growth of 50% in dualculture and of 90% through VOCs. Moreover, in vivo antagonistic assays revealed a visible decrease of gray mold rot symptoms on apples confirming the potential of S. bacillaris as BCA. GC-MS analysis of the ciders obtained showed increased concentrations in the sequential fermentation of some higher alcohols and terpenes, positively correlated with the cider aromatic quality, and suggested the involvement of benzyl alcohol, known for its antimicrobial action, in the biocontrol efficacy.

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Lemos, WJF; Binati, RL; Felis, GE; Slaghenaufi, D; Ugliano, M; Torriani, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of Benzyl Alcohol. Recently I am researching about BETA-LACTAM ANTIBIOTICS; RESISTANCE, Saw an article supported by the University Grants Commission-Basic Science Research (UGC-BSR), New Delhi, India; UGC, New Delhi, IndiaUniversity Grants Commission, India; National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sahu, A; Sahu, P; Agrawal, R. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

A series of hybrid antimicrobial compounds were prepared by carboxylic acid protection of 6-aminopenicillanic acid using benzyl alcohol and thionyl chloride succeeded by azide displacement using trifluoromethanesulfonyl azide in dichloromethane. The azide thus formed was reacted with substituted alkynes to furnish benzyl-protected penicillin-triazole conjugates. Benzyl deprotection of the conjugates resulted in furnishing PNTCs under water methanol mixture using Pd/C as a catalyst. The PNTCs (7a-j) formed were screened for in vitro antibacterial potency against pathogenic strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes and antifungal potency against Candida albicans, Aspergillus niger, and Aspergillus clavatus. Further antimicrobial evaluation revealed compounds 7c, 7d, 7e, 7g, and 7i to be the most compounds of the series with minimum inhibitory concentration value for antibacterial in the range 0.5-50 mu g/mL and for antifungal in the range 9-300 mu g/mL. Toxicological analysis documented for compounds 7c, 7d, 7e, 7g, and 7i revealed compound 7i to be the most promising member of the series with 1000 and 500 mg/kg LD50, and no-observed-adverse-effect level to facilitate future clinical studies of the same.

Application In Synthesis of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Sahu, A; Sahu, P; Agrawal, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Mingalev, PG; Lisichkin, GV in [Mingalev, P. G.; Lisichkin, G. V.] Moscow MV Lomonosov State Univ, Fac Chem, Moscow 119234, Russia published Maghemite as a Catalyst for Oxidation of Alcohols with Air in 2020, Cited 7. Name: Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

The possibility of using maghemite (gamma-iron(III) oxide) as a catalyst for the oxidation of alcohols with atmospheric oxygen has been explored. It has been shown that maghemite is active in the oxidation of benzyl alcohols. In the case of benzyl alcohol, the oxidation leads to benzaldehyde with nearly 100% selectivity. It has been found that the addition of small amounts of basic cocatalysts can substantially increase the yield of the target products.

Name: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Mingalev, PG; Lisichkin, GV or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Belyaev, ES; Shkirdova, AO; Kozhemyakin, GL; Tyurin, VS; Emets, VV; Grinberg, VA; Cheshkov, DA; Ponomarev, GV; Tafeenko, VA; Radchenko, AS; Kostyukov, AA; Egorov, AE; Kuzmin, VA; Zamilatskov, IA in [Belyaev, Evgeny S.; Shkirdova, Alena O.; Kozhemyakin, Grigory L.; Tyurin, Vladimir S.; Emets, Victor V.; Grinberg, Vitali A.; Cheshkov, Dmitry A.; Zamilatskov, Ilya A.] Russian Acad Sci, AN Frumkin Inst Phys Chem & Electrochem, Leninskiy Prospect 31-4, Moscow 119071, Russia; [Cheshkov, Dmitry A.] State Sci Res Inst Chem & Technol Organoelement C, Sh Entuziastov 38, Moscow 105118, Russia; [Ponomarev, Gelii, V] Res Inst Biomed Chem, Pogodinskaya St 10-8, Moscow 119121, Russia; [Tafeenko, Victor A.] Moscow MV Lomonosov State Univ, Chem Dept, Leninskiye Gory 1-3, Moscow 119899, Russia; [Radchenko, Alexandra S.; Kostyukov, Alexey A.; Egorov, Anton E.; Kuzmin, Vladimir A.] Russian Acad Sci, Emanuel Inst Biochem Phys, Kosygin St 4, Moscow 119334, Russia published Azines of porphyrinoids. Does azine provide conjugation between chromophores? in 2021.0, Cited 71.0. Product Details of 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A new approach to functionalize porphyrinoids was developed based on the Vilsmeier formylation followed by the azine formation and a new class of the compounds namely azines of porphyrinoids was obtained. Variously substituted azine porphyrins, chlorins and their dyads were synthesized, and their structural and electronic parameters were studied with X-ray diffraction analysis, electronic absorption and emission spectra, electrochemistry and DFT calculations. Azine represents a very peculiar bridge with an unclear conjugation ability affecting optical properties of chromophores. This work was aimed to reveal azine properties and the influence of the azine bridge on the chromophores linked. The results of investigation allowed to conclude that azine bridge can partly be regarded as a conjugation switch with a high threshold level of switching, where limited conjugation in the ground state can be greatly increased at higher energy states of the azine molecule.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Belyaev, ES; Shkirdova, AO; Kozhemyakin, GL; Tyurin, VS; Emets, VV; Grinberg, VA; Cheshkov, DA; Ponomarev, GV; Tafeenko, VA; Radchenko, AS; Kostyukov, AA; Egorov, AE; Kuzmin, VA; Zamilatskov, IA or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H8O. In 2019.0 RSC ADV published article about RANEY-NICKEL; DESIGN; DESULFURIZATION; HYDROGENOLYSIS; ACTIVATION; EFFICIENCY; REDUCTION; RADICALS; TEMPO in [Kim, Min Joon; Gaube, Sophie M.; Beh, Michael H. R.; Smith, Craig D.; Thompson, Alison] Dalhousie Univ, Dept Chem, POB 15000, Halifax, NS B3H 4R2, Canada in 2019.0, Cited 42.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

2-Functionalised pyrroles exhibit considerable synthetic utility. Herein, the synthesis and reactivity of 2-thionoester (-C(S)OR) pyrroles is reported. 2-Thionoester pyrroles were synthesised using a Knorr-type approach from aliphatic starting materials. 2-Thionoester pyrroles were reduced to the corresponding 2-formyl pyrroles, or the deuterated formyl variant, in one step using RANEY (R) nickel, thereby removing the need for the much-utilised hydrolysis/decarboxylation/formylation steps that are typically required to convert Knorr-type 2-carboxylate pyrroles into 2-formyl pyrroles. 2-Thionoester pyrroles proved tolerant of typical functional group interconversions for which the parent 2-carboxylate pyrroles have become known.

Computed Properties of C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Kim, MJ; Gaube, SM; Beh, MHR; Smith, CD; Thompson, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Simple Transformation of Hierarchical Hollow Structures by Reduction of Metal-Organic Frameworks and Their Catalytic Activity in the Oxidation of Benzyl Alcohol WOS:000471132500012 published article about ONE-POT SYNTHESIS; AEROBIC OXIDATION; LITHIUM-STORAGE; CU-BTC; SPHERES; MICROSPHERES; NANOSTRUCTURES; TEMPLATES; ENERGY in [Ju, Suhyun; Yusuf, Mohammad; Jang, Seongwan; Kang, Hyuntae; Kim, Soohee; Park, Kang Hyun] Pusan Natl Univ, Dept Chem, Busan 46241, South Korea; [Ju, Suhyun; Yusuf, Mohammad; Jang, Seongwan; Kang, Hyuntae; Kim, Soohee; Park, Kang Hyun] Pusan Natl Univ, Chem Inst Funct Mat, Busan 46241, South Korea in 2019.0, Cited 49.0. Safety of Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Metal-organic framework (MOF)-based derivatives have been found to be promising heterogeneous catalysts for organic transformations. Herein, hollow-structure Cu-MOFs derived by reduction of Cu-3(BTC)(2) (BTC=1,3,5-benzenetricarboxylate; denoted as RCB) were prepared by using hydrazine hydrate as a reducing agent under various conditions. The influence of hydrazine hydrate induced the structure of Cu-3(BTC)(2) and led to dynamic variation in the interior and exterior as well as oxidation states of the Cu ion. The synthesized materials were characterized by SEM, TEM, N-2 sorption isotherms, XRD, and XPS. The product of the catalytic reaction was observed by GC-MS. In addition, the prepared RCBs were found to have excellent catalytic activity and selectivity for benzyl alcohol oxidation when assisted by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO).

Safety of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Ju, S; Yusuf, M; Jang, S; Kang, H; Kim, S; Park, KH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 4-Methoxybenzaldehyde. Authors Dale, HJA; Nottingham, C; Poree, C; Lloyd-Jones, GC in AMER CHEMICAL SOC published article about in [Dale, Harvey J. A.; Nottingham, Chris; Poree, Carl; Lloyd-Jones, Guy C.] Univ Edinburgh, Sch Chem, Edinburgh EH9 3FJ, Midlothian, Scotland in 2021.0, Cited 50.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Alkylidene carbenes undergo rapid inter- and intramolecular reactions and rearrangements, including 1,2-migrations of beta-substituents to generate alkynes. Their propensity for substituent migration exerts profound influence over the broader utility of allcylidene carbene intermediates, yet prior efforts to categorize 1,2-migratory aptitude in these elusive species have been hampered by disparate modes of carbene generation, ultrashort carbene lifetimes, mechanistic ambiguities, and the need to individually prepare a series of C-13-labeled precursors. Herein we report on the rearrangement of C-13-alkylidene carbenes generated in situ by the homologation of carbonyl compounds with [C-13]-Li-TMS-diazomethane, an approach that obviates the need for isotopically labeled substrates and has expedited a systematic investigation (C-13{H-1} NMR, DLPNO-CCSD(T)) of migratory aptitudes in an unprecedented range of more than 30 alkylidene carbenes. Hammett analyses of the reactions of 26 differentially substituted benzophenones reveal several counterintuitive features of 1,2-migration in alkylidene carbenes that may prove of utility in the study and synthetic application of unsaturated carbenes more generally.

Quality Control of 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Dale, HJA; Nottingham, C; Poree, C; Lloyd-Jones, GC or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 100-51-6. Authors Bizimana, T; Hagen, N; Gnegel, G; Kayumba, PC; Heide, L in PUBLIC LIBRARY SCIENCE published article about in [Bizimana, Thomas] Univ Rwanda, Coll Med & Hlth Sci CMHS, Sch Med & Pharm, Dept Pharm, Kigali, Rwanda; [Hagen, Nhomsai; Gnegel, Gesa; Heide, Lutz] Eberhard Karls Univ Tubingen, Pharmaceut Inst, Tubingen, Germany; [Kayumba, Pierre Claver] Univ Rwanda, East African Community Reg Ctr Excellence Vaccine, Kigali, Rwanda in 2021.0, Cited 47.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Sustainable Development Goal 3.1 calls for a reduction of the maternal mortality ratio to less than 70 per 100,000 live births by 2030. The most important cause of maternal mortality is post-partum haemorrhage (PPH). Oxytocin injections and misoprostol tablets are medicines of first choice for the management of PPH in low- and middle-income countries (LMICs). Unfortunately, both substances are chemically unstable, and previous studies have revealed serious quality problems of these medicines in LMICs. The present study is the first report on their quality in Rwanda. From 40 randomly selected health facilities (hospitals, health centers, retail pharmacies and private clinics) in different parts of Rwanda, as well as from six wholesalers and government stores, oxytocin injections and misoprostol tablets were collected. Oxytocin storage temperatures in the health facilities were monitored for six months using temperature data loggers, and found to correctly follow the storage requirements stated by the manufacturers (2-8 degrees C, or room temperature) with few minor deviations. Oxytocin injections (57 samples, representing seven batches of four brands) were tested for their oxytocin content and pH value according to the United States Pharmacopeia. Twenty-four samples from three European manufacturers passed all tests. However, all nine samples of one batch of a Chinese manufacturer showed an excessive content of oxytocin (range 117.2-121.5% of the declared amount). Another batch of the same manufacturer showed extreme variations of the concentration of the preservative benzyl alcohol. Misoprostol tablets (25 samples, representing ten batches of six brands) were tested for content and dissolution according to the International Pharmacopoeia. Fifteen samples passed, but all 10 samples of two brands from India failed with extreme deviations, containing only 42.5-48.7% of the stated amount of misoprostol. In conclusion, oxytocin quality in Rwanda was better than reported from other African countries. However, two extremely substandard brands of misoprostol tablets were found. The Rwandan authorities reacted quickly and efficiently, and recalled these substandard medicines from the market. For oxytocin and misoprostol, with their well-known problems of quality and stability, procurement should possibly be restricted to medicines which are WHO-prequalified or which have been manufactured in countries with stringent regulatory authorities.

About Benzyl Alcohol, If you have any questions, you can contact Bizimana, T; Hagen, N; Gnegel, G; Kayumba, PC; Heide, L or concate me.. Product Details of 100-51-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles