Tag: M.W=100-150

An article Synthesis and characterization of a novel organic-inorganic hybrid salt and its application as a highly effectual Bronsted-Lewis acidic catalyst for the production of N,N ‘-alkylidene bisamides WOS:000576690800001 published article about DICATIONIC IONIC LIQUID; EFFICIENT CATALYST; SYMMETRICAL BISAMIDES; THERMAL-ANALYSIS; PERFORMANCE; LIGANDS; AMIDES in [Zare, Abdolkarim; Monfared, Fatemeh; Sajadikhah, Seyed Sajad] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran in 2021, Cited 54. COA of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

In this research, a novel organic-inorganic hybrid salt, namely,N-1,N-1,N-2,N-2-tetramethyl-N-1,N-2-bis(sulfo)ethane-1,2-diaminium tetrachloroferrate ([TMBSED][FeCl4](2)) was prepared and characterized by Fourier-transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), elemental mapping, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), thermal gravimetric (TG), differential thermal gravimetric (DTG), and vibrating-sample magnetometry (VSM) analyses. Catalytic activity of the hybrid salt was tested for the synthesis ofN,N ‘-alkylidene bisamides through the reaction of benzamide (2 eq.) and aromatic aldehydes (1 eq.) under solvent-free conditions in which the products were obtained in high yields and short reaction times. The catalyst was superior to many of the reported catalysts in terms of two or more of these factors: the reaction medium and temperature, yield, time, and turnover frequency (TOF). [TMBSED][FeCl4](2)is a Bronsted-Lewis acidic catalyst; there are two SO3H groups (as Bronsted acidic sites) and two tetrachloroferrate anions (as Lewis acidic sites) in its structure. Highly effectiveness of the catalyst for the synthesis ofN,N ‘-alkylidene bisamides can be attributed to synergy of the Bronsted and Lewis acids and also possessing two sites of each acid.

COA of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zare, A; Monfared, F; Sajadikhah, SS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2021 ACS CATAL published article about RESONANCE RAMAN; CATALYSIS; AMINATIONS; COMPLEXES; CHEMISTRY; AMIDES; AZIDES in [Chatterjee, Basujit; Jena, Soumyashree; Chugh, Vishal; Weyhermueller, Thomas; Werle, Christophe] Max Planck Inst Chem Energy Convers, D-45470 Mulheim, Germany; [Chatterjee, Basujit; Jena, Soumyashree; Chugh, Vishal; Werle, Christophe] Ruhr Univ Bochum, D-44801 Bochum, Germany in 2021, Cited 130. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Formula: C8H8O2

The direct synthesis of amides and nitriles from readily available aldehyde precursors provides access to functional groups of major synthetic utility. To date, most reliable catalytic methods have typically been optimized to supply one product exclusively. Herein, we describe an approach centered on an operationally simple iron-based system that, depending on the reaction conditions, selectively addresses either the C=O or C-H bond of aldehydes. This way, two divergent reaction pathways can be opened to furnish both products in high yields and selectivities under mild reaction conditions. The catalyst system takes advantage of iron’s dual reactivity capable of acting as (1) a Lewis acid and (2) a nitrene transfer platform to govern the aldehyde building block. The present transformation offers a rare control over the selectivity on the basis of the iron system’s ionic nature. This approach expands the repertoire of protocols for amide and nitrile synthesis and shows that fine adjustments of the catalyst system’s molecular environment can supply control over bond activation processes, thus providing easy access to various products from primary building blocks.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Chatterjee, B; Jena, S; Chugh, V; Weyhermuller, T; Werle, C or concate me.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Phytochemical components and biological activities of essential oils from three selected medicinal plants WOS:000613173400003 published article about IN-VITRO; MYRISTICA-FRAGRANS; ANGELICA-DAHURICA; PATCHOULI ALCOHOL; INFLAMMATION; INHIBITION in [Zhang, Lanyue; Ye, Mao; Shi, Yaohui; Zhu, Haiping; Chi, Lejing; Pan, Chunxing; Xu, Yani; Li, Chunlian] Guangdong Univ Technol, Sch Biomed & Pharmaceut Sci, Guangzhou 510006, Peoples R China; [Xiang, Hongping] Guangdong Univ Technol, Sch Mat & Energy, Guangzhou 510006, Peoples R China; [Zheng, Xi] Rutgers State Univ, Susan Lehman Cullman Lab Canc Res, Ernest Mario Sch Pharm, Dept Chem Biol, 164 Frelinghuysen Rd, Piscataway, NJ 08854 USA in 2021, Cited 42. Product Details of 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Essential oils extracted from herbs have been utilized in food and medicine on the account of their increasing physicochemical characteristics. This present study aimed to investigate the phytochemical components, antiinflammatory, cytotoxic, anti-microbial and anti-oxidant activities of essential oils from Pogostemon cablin (P. cablin), Angelica dahurica (A. dahurica) and Myristica fragrans (M. fragrans), all belong to medicine food homology herbs. Approximately 107 components were identified by gas chromatography mass spectrometry (GC-MS) from these essential oils. The main compounds of P. cablin essential oils (PCEOs) were patchouli alcohol (27.72%), alpha-buaiacene (17.94%) and alpha-guaiene (14.15%); in A. dahurica essential oils (ADEOs) were anethole (24.91%) and cinnamaldehyde (18.35%); and in M. fragrans essential oils (MFEOs) were (1S)-(-)-alpha-pinene (23.39%), alpha-terpineol (18.60%) and caryophyllene (10.34%). These essential oils were found to have strong antiinflammatory activities through decreasing the production of cyclooxygenase-2 (COX-2), interleukin-6 (IL-6), nuclear factor-kappa B p65 (P65) and tumor necrosis factor-alpha (TNF-alpha). These essential oils also had significant anti-bacterial activities against both Gram-negative and Gram-positive strains and anti-fungal activities. Moreover, effective anti-oxidant properties of three essential oils were estimated (0.001962%-0.19%). The study also explored the effect of these essential oils on the survival of Brain microglia (BV2) microglial cells (IC50 = 145.50-281.52 mu g/mL). Based on these bioactivities, these essential oils could be used as food additives, fragrances, cosmetics and health products.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zhang, LY; Ye, M; Shi, YH; Zhu, HP; Chi, LJ; Pan, CX; Xu, YN; Zheng, X; Xiang, HP; Li, CL or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Mitra, S; Mukherjee, S in [Mitra, Sankash; Mukherjee, Santanu] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India published Iridium-Catalyzed Asymmetric Allylic Alkylation of Deconjugated Butyrolactams in 2021.0, Cited 59.0. Recommanded Product: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Compared with the ever-growing list of nonprochiral nucleophiles in Ir-catalyzed asymmetric allylic substitution reactions, prochiral nucleophiles are less studied. We present a new prochiral nucleophile, namely, deconjugated butyrolactam, for Ir-catalyzed asymmetric allylic alkylation (AAA). This reaction provides access to a-allyl deconjugated butyrolactams with a moderate to good dr and an excellent er. This is the first AAA reaction of deconjugated butyrolactams. Allyl transposition through Cope rearrangement appears to proceed stereospecifically to form.-allyl conjugated butyrolactams.

Recommanded Product: 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Mitra, S; Mukherjee, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 123-11-5. In 2021 DALTON T published article about CATALYZED OXIDATIVE SYNTHESIS; ONE-POT SYNTHESIS; 4(3H)-QUINAZOLINONE DERIVATIVES; CASCADE SYNTHESIS; BENZYL ALCOHOLS; QUINAZOLINONES; METAL; EFFICIENT; SILICA; OXIDE in [Gupta, Radhika; Arora, Gunjan; Yadav, Priya; Dixit, Ranjana; Sharma, Rakesh Kumar] Univ Delhi, Green Chem Network Ctr, Dept Chem, Delhi 110007, India; [Yadav, Priya; Srivastava, Anju] Univ Delhi, Hindu Coll, Dept Chem, Delhi 110007, India in 2021, Cited 74. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

In the present work, we report the design and fabrication of a copper-containing ionic liquid supported magnetic nanocatalyst via a convenient and straightforward synthetic approach for the formation of 2-phenylquinazolin-4(3H)-ones using o-aminobenzamide and benzaldehydes as the reaction partners. The successful formation and properties of the as-prepared catalyst have been thoroughly investigated using diverse physico-chemical techniques including FT-IR, XRD, FE-SEM, TEM, ICP, VSM, BET and TGA. Using this nanocatalytic system, a variety of 2-phenylquinazolin-4(3H)-ones are synthesized in excellent yields with operational ease and short reaction times in an environmentally preferable solvent under open air and without using any external oxidizing agent. Besides, the catalyst possessed facile magnetic recoverability and remarkable reusability for six consecutive runs without any appreciable decrease in the catalytic efficiency.

SDS of cas: 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Gupta, R; Arora, G; Yadav, P; Dixit, R; Srivastava, A; Sharma, RK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about SYRIAN CIVIL-WAR; IN-VITRO; CUTANEOUS LEISHMANIASIS; ANTILEISHMANIAL ACTIVITY; ANTIBACTERIAL ACTIVITY; MEDICINAL-PLANTS; NATURAL-PRODUCTS; CHENOPODIUM-AMBROSIOIDES; TRADITIONAL MEDICINE; MAIN COMPONENTS, Saw an article supported by the Consejo Nacional de Ciencia y Tecnologia (CONACYT)Consejo Nacional de Ciencia y Tecnologia (CONACyT) [298060]; grant FOFI-UAQ [FCQ-2018-11]; CONACYT, MexicoConsejo Nacional de Ciencia y Tecnologia (CONACyT) [0224747]. Published in MDPI in BASEL ,Authors: Delgado-Altamirano, R; Lopez-Palma, RI; Monzote, L; Delgado-Dominguez, J; Becker, I; Rivero-Cruz, JF; Esturau-Escofet, N; Vazquez-Landaverde, PA; Rojas-Molina, A. The CAS is 80-59-1. Through research, I have a further understanding and discovery of (E)-2-Methylbut-2-enoic acid. HPLC of Formula: C5H8O2

Lantana camara (L.) is employed by several ethnical groups to treat numerous diseases. Although there are no ethnomedical reports on its use against leishmaniasis, organic extracts prepared from L. camara were shown to display leishmanicidal activity. In the present study, we carried out a bioassay-guided fractionation of the dichloromethane extract from Mexican L. camara in order to identify the compounds responsible for the leishmanicidal activity. Eighteen chromatographic fractions (FI-FXVIII) were evaluated in vitro against Leishmania mexicana and L. amazonensis. FII, FX, FXI, FXV, and FXVI showed significant activity against both Leishmania strains, the most potent of which was FXV. Eicosane (1), squalene (2), -ionone (3), caryophyllene oxide (4), -caryophyllene (5), hexanoic acid (6), tiglic acid (7), a mixture of lantanilic (8) and camaric (9) acids, and lantadene B (10) were identified and obtained from the active fractions and evaluated for their leishmanicidal activity. The mixture of lantanilic (8) and camaric (9) acids (79%/21%) was the most potent one (half maximal inhibitory concentration (IC50) = 12.02 +/- 0.36 M). This study indicates that this cultivar of L. camara has high potential for the development of phytomedicines or as a source of natural products, which might represent lead compounds for the design of new drugs against leishmaniasis.

HPLC of Formula: C5H8O2. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Delgado-Altamirano, R; Lopez-Palma, RI; Monzote, L; Delgado-Dominguez, J; Becker, I; Rivero-Cruz, JF; Esturau-Escofet, N; Vazquez-Landaverde, PA; Rojas-Molina, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C8H8O2. In 2021 BIOORG MED CHEM LETT published article about CATALYZED N-ALKYLATION; BIOLOGICAL-ACTIVITIES; ANTIOXIDANT ACTIVITY; DERIVATIVES; ANTICONVULSANT; FILMS; ALCOHOLS; DESIGN; AMINES in [Kumar, C. B. Pradeep] Malnad Coll Engn, Dept Chem, Hassan 573202, India; [Raghu, M. S.; Parashuram, L.] New Horizon Coll Engn, Dept Chem, Bengaluru 560103, India; [Prathibha, B. S.; Prashanth, M. K.] BNM Inst Technol, Dept Chem, Bengaluru 560070, India; [Kanthimathi, G.] Ramco Inst Technol, Dept Chem, Rajapalayam 626117, Tamil Nadu, India; [Kumar, K. Yogesh] Jain Univ, Sch Engn & Technol, Dept Chem, Ramanagara 562112, India; [Alharthi, Fahad A.] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia in 2021, Cited 50. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A Ta2O5-anchored-piperidine-4-carboxylic acid (PPCA) nanoparticle has been synthesized and characterized. It was then used as a highly effective nanocatalyst for the synthesis of quinolin-2(1H)-one derivatives through C-O bond functionalization. The special advantage of this heterogeneous solid catalyst is the reusability of the catalyst for up to five cycles without any noticeable reduction in product yields. In comparison, healthy reaction profiles, wide substrate scope, excellent yields and easy workup conditions are the notable highlights of this approach. All the compounds were tested for their anticancer activity against MCF-7 (human breast), HepG2 (human liver), HCT116 (human colorectal), and PC-3 (human prostate) cancer cell lines with the MTT assay. All the compounds were shown to have moderate to good inhibitory effects on tested cancer cell lines. Besides, compounds 5b, 5c and 5d showed good selectivity against epidermal growth factor receptor-tyrosine kinase (EGFR-TK). Molecular docking results showed that active compounds showed a good affinity towards EGFR kinase (PDB ID: 6V6O) by forming two hydrogen bonds with Cys-797 and Tyr-801. All the compounds were screened for computational ADMET and Lipinski analysis.

COA of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Kumar, CBP; Raghu, MS; Prathibha, BS; Prashanth, MK; Kanthimathi, G; Kumar, KY; Parashuram, L; Alharthi, FA or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about EXCITED-STATE PROPERTIES; P-HYDROXYPHENACYL; (COUMARIN-4-YL)METHYL DERIVATIVES; DEACTIVATION BEHAVIOR; AQUEOUS-SOLUTION; PHOTOCHEMISTRY; PHOTOCLEAVAGE; PHOTORELEASE; ESTERS; PHOTODECARBOXYLATION, Saw an article supported by the Kansas University Endowment Association; National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA; National Science FoundationNational Science Foundation (NSF) [CHE-1807729]; FCT – Foundation for Science and TechnologyPortuguese Foundation for Science and Technology [UID/Multi/04326/2019]; operational program CRESC Algarve 2020 [EMBRC.PT ALG-01-0145-FEDER-022121]; operational program COMPETE 2020 [EMBRC.PT ALG-01-0145-FEDER-022121]. Published in SPRINGERNATURE in LONDON ,Authors: Field, T; Peterson, J; Ma, CC; Jagadesan, P; Da Silva, JP; Rubina, M; Ramamurthy, V; Givens, RS. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone. Category: indole-building-block

Extending the applications of Photoremovable Protecting Groups (PPGs) to cage phenols has generally met with unusually complex PPG byproducts. In this study, we demonstrate that thep-hydroxyphenacyl (pHP) cage for both simple and complex phenolics, including tyrosine, dispenses free phenols. With the simpler unsubstituted phenols, the reaction is governed by their Bronsted Leaving Group ability. On the other hand, the byproducts of the cage vary with these phenols. For the more acidic phenols the cage byproduct follows the Favorskii rearrangement to formp-hydroxyphenylacetic acid whereas for the weaker phenols other reactions such as reduction and hydrolysis begin to emerge. When the photolysis is conducted in octa acid (OA) containers, non-Favorskii, unrearranged fragments of the cage and other byproducts arise.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Field, T; Peterson, J; Ma, CC; Jagadesan, P; Da Silva, JP; Rubina, M; Ramamurthy, V; Givens, RS or concate me.. Category: indole-building-block

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Formal enantioselective synthesis of nhatrangin A WOS:000519640500012 published article about MICHAEL ADDITION; APLYSIATOXIN DERIVATIVES; STEREOSELECTIVE ACCESS; DEBROMOAPLYSIATOXIN; ALDEHYDES; STEREOCHEMISTRIES; INHIBITION; EFFICIENT; ALCOHOLS; CATALYST in [Feuillastre, Sophie; Raffier, Ludovic; Pelotier, Beatrice; Piva, Olivier] Univ Claude Bernard Lyon 1, Univ Lyon, Inst Chim & Biochim Mol & Supramol, MIR 5246,Equipe SURCOOF,CNRS,INSA Lyon,CPE Lyon, Bat Raulin,43 Bd 11 Novembre 1918, F-69622 Villeurbanne, France in 2020.0, Cited 50.0. Application In Synthesis of 3-Hydroxybenzaldehyde. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

A new and straightforward synthesis of the C-1-C-7 core fragment of nhatrangin A was achieved in 14 steps from achiral 3-hydroxybenzaldehyde, without the need of chiral reagents or enzymatic resolution to introduce the chiral centers. The key asymmetric steps include in particular a highly enantioselective organocatalyzed Michael addition on an aryl vinyl ketone, a Sharpless asymmetric epoxidation and a subsequent regioselective ring opening of the resulting chiral epoxide. This work represents the first formal enantioselective synthesis of nhatrangin A.

Application In Synthesis of 3-Hydroxybenzaldehyde. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Feuillastre, S; Raffier, L; Pelotier, B; Piva, O or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 100-51-6. Recently I am researching about FLORAL SCENT; COMPONENTS, Saw an article supported by the National Research Foundation of Korea (NRF) – Korea government (MSIT) [NRF-2019RIA2C1009623]. Published in ELSEVIER in AMSTERDAM ,Authors: Gil, CS; Lim, ST; Lim, YJ; Jung, KH; Na, JK; Eom, SH. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

Volatile content during postharvest is a critical factor affecting the quality of rose products. However, changes in the volatile content of cut rose flowers during vase life have not yet been identified although the maturity of flower petals may result in the significant changes of volatile profiles. The present study investigated volatile changes in the petals of two rose varieties, ‘Fuego’ exhibited to longer vase life and ‘Red eagle, during vase life. ‘Fuego’ petals contained 31 volatiles, of which 12 increased and 11 decreased in content during vase life. ‘Red Eagle’ petals contained 37 volatiles, of which 9 increased and 19 decreased. The major components that increased during vase life included 2-ethylhexan-1-ol and phenylmethanol in ‘Fuego’ and hexan-1-ol and 2-phenylacetaldehyde in both cultivars, whereas the major components that decreased during vase life included methyl butanoate in ‘Fuego’, 3,5-dimethoxytoluene in ‘Red Eagle’, and 2-methylhexane in both cultivars. The total volatile content was maintained in ‘Fuego’ petals during the 6-day vase life, despite the changes in the content of individual volatile compound. By contrast, the total volatile content of ‘Red Eagle’ petals significantly decreased during vase life. Additionally, the volatile compounds that increased in content were relatively small molecules (<= C-8), whereas those that decreased in content during vase life were relatively large molecules (>= C-9). These results suggest that the analysis of volatile changes during vase life contribute to the harvest time selection of rose flowers and the determination of petal stages used for essential oil in many rose varieties.

Recommanded Product: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Gil, CS; Lim, ST; Lim, YJ; Jung, KH; Na, JK; Eom, SH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles