Tag: M.W=100-150

Recommanded Product: Benzyl Alcohol. I found the field of Food Science & Technology very interesting. Saw the article Protein hydrolysates of porcine hemoglobin and blood: Peptide characteristics in relation to taste attributes and formation of volatile compounds published in 2019.0, Reprint Addresses Lametsch, R (corresponding author), Univ Copenhagen, Fac Sci, Dept Food Sci, Rolighedsvej 26, DK-1958 Frederiksberg C, Denmark.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol.

The objective of this study was to investigate the impact of endo- and exo-peptidase treatment on certain structural characteristics of peptides and volatile compounds of porcine hemoglobin and whole blood hydrolysates. Porcine hemoglobin and whole blood were hydrolyzed by endo- and exo-peptidases. The presence of exopeptidases reduced the bitterness and altered the volatile profiles of protein hydrolysates. Exopeptidase treatment can release terminal amino acids from peptides, which in turn may contribute to formation of volatile compounds by Maillard reactions. In contrast, endopeptidases conferred a slightly bitter taste and different volatile profiles. For hemoglobin hydrolysates, principal component analysis revealed that proteases were categorized into three groups based on endo- or exo-peptidase activity. Whole blood is a more complex raw material, yet the proteases were still categorized in a similar fashion. This work contributes to understanding structural characteristics responsible for taste and volatile profiles of protein hydrolysates.

Recommanded Product: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Fu, Y; Bak, KH; Liu, J; De Gobba, C; Tostesen, M; Hansen, ET; Petersen, MA; Ruiz-Carrascal, J; Bredie, WLP; Lametsch, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Inaloo, ID; Majnooni, S in [Inaloo, Iman Dindarloo] Shiraz Univ, Coll Sci, Chem Dept, Shiraz 7194684795, Iran; [Majnooni, Sahar] Univ Isfahan, Chem Dept, Esfahan 8174673441, Iran published A Fe3O4@SiO2/Schiff Base/Pd Complex as an Efficient Heterogeneous and Recyclable Nanocatalyst for One-Pot Domino Synthesis of Carbamates and Unsymmetrical Ureas in 2019.0, Cited 165.0. Formula: C8H8O2. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A palladium-catalyzed domino method for the direct synthesis of carbamates and ureas has been developed by using readily available and economical starting materials (aryl halide, carbon monoxide, sodium azide, amines and alcohols) in a one-pot approach. The domino process underwent carbonylation, Curtius rearrangement, and nucleophilic addition. This protocol provides a step-economical and highly efficient reaction to access the wide range of valuable carbamates, symmetrical and unsymmetrical ureas with high yields under remarkable mild reaction conditions that are important factors in pharmaceutical science, biochemistry and agricultural industries. Furthermore, the magnetically recoverable nanocatalyst (Fe3O4@SiO2/Pd(II)) can be conveniently and swiftly recycled using external magnet and reused at least for seven times without noticeable loss of its catalytic activity.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Inaloo, ID; Majnooni, S or concate me.. Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C5H8O2. Ning, S; Zhang, L; Ma, JJ; Chen, L; Zeng, GY; Yang, C; Zhou, YJ; Guo, XL; Deng, X in [Ning, Shuai; Ma, Jinjin; Chen, Lan; Zeng, Guangyao; Zhou, Yingjun; Deng, Xu] Cent South Univ, Xiangya Sch Pharmaceut Sci, Changsha 410013, Hunan, Peoples R China; [Zhang, Lei; Yang, Chao; Guo, Xiaoli] Huazhong Agr Univ, State Key Lab Agr Microbiol, Coll Plant Sci & Technol, Wuhan 430070, Hubei, Peoples R China published Modular and scalable synthesis of nematode pheromone ascarosides: implications in eliciting plant defense response in 2020, Cited 43. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1.

A highly efficient and modular synthesis of nematode pheromone ascarosides was developed, which highlights a 4-step scalable synthesis of the common intermediate 10 in 23% yield from commercially available l-rhamnose by using orthoesterification/benzylation/orthoester rearrangement as the key step. Six diverse ascarosides were synthesized accordingly. Notably, biological investigations revealed that ascr#1 and ascr#18 treatment resulted in enhanced callose accumulation in Arabidopsis leaves. And ascr#18 also increased the expression of defense-related genes such as PR1, PDF1.2, LOX2 and AOS, which might contribute to the enhanced plant defense responses. This study not only allows a facile access to 1-O, 2-O, and 4-O substituted ascarosides, but also provides valuable insights into their biological activities in inducing plant defense response, as well as their mode of action.

HPLC of Formula: C5H8O2. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Ning, S; Zhang, L; Ma, JJ; Chen, L; Zeng, GY; Yang, C; Zhou, YJ; Guo, XL; Deng, X or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Nontarget Analysis of Oxygenates in Catalytic Fast Pyrolysis Biocrudes by Supercritical Fluid Chromatography High-Resolution Mass Spectrometry WOS:000456350700027 published article about BIO-OILS; BIOMASS; TEMPERATURE; SEPARATION; ALIGNMENT; LIGNIN in [Lubeck, Josephine S.; Tomasi, Giorgio; Poulsen, Kristoffer G.; Mante, Ofei D.; Dayton, David C.; Verdier, Sylvain; Christensen, Jan H.] Univ Copenhagen, Fac Sci, Dept Plant & Environm Sci, Thorvaldsensvej 40, DK-1871 Frederiksberg, Denmark; [Verdier, Sylvain] Haldor Topsoe Res Labs, Haldor Topsoes Alle 1, DK-2800 Lyngby, Denmark; [Mante, Ofei D.; Dayton, David C.] RTI Int, Energy Technol Div, 3040 East Cornwallis Rd, Res Triangle Pk, NC 27709 USA in 2019.0, Cited 50.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4. Formula: C7H6O2

Catalytic fast pyrolysis (CFP) biocrudes can comprise up to 30 wt % of oxygen content in compounds such as polyphenols, acids, carbonyls, and anhydrosugars and thus require upgrading by, e.g., hydrotreatment, to produce transport fuels. The chemical characterization of phenolic and acidic compounds in biocrudes is of great importance to optimize the CFP process. In this study, an analytical workflow is proposed for nontarget chemical fingerprinting analysis of CFP biocrudes using supercritical fluid chromatography high-resolution mass spectrometry (SFC-HRMS) with negative electrospray ionization (ESI-), followed by multivariate data analysis. The method was developed and tested on five biocrude samples from loblolly pine (Pinus taeda) with varying oxygen content (14.9-28.8 wt % wet basis) due to different CFP conditions. The pixel-based analysis displayed chemical variation between all samples. Twenty-four regions of interest were tentatively identified, including mono- and polyphenols, fatty acids, and methylated and methoxylated phenols. The identification workflow and MS/MS analysis were prioritized on the peaks with the highest relative concentration. The developed SFC-ESI–HRMS method shows high repeatability and analyzed oxygen-containing compounds with hydroxyl and/or carboxyl moieties in combination with other moieties of up to 400 Da.

Formula: C7H6O2. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Lubeck, JS; Tomasi, G; Poulsen, KG; Mante, OD; Dayton, DC; Verdier, S; Christensen, JH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2020 ACS OMEGA published article about BENZYNE-CLICK CHEMISTRY; FACILE N-ARYLATION; O-ARYLATION; NUCLEOPHILIC-SUBSTITUTION; SELECTIVE SYNTHESIS; GENERATION; EFFICIENT; PHENOLS; MAGNESIUM; REAGENTS in [Muraca, Ana Carolina A.; Raminelli, Cristiano] Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972270 Diadema, Brazil in 2020, Cited 107. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Computed Properties of C7H8O2

A class of aryne precursors, that is, 2-(trimethylsilyl)aryl 4-chlorobenzenesulfonates, has been developed through well-established synthetic routes, which allow the formation of arynes under relatively mild conditions. All the aryne precursors were obtained from phenols and 4-chlorobenzenesulfonyl chloride, an inexpensive and easy-to-handle reagent with relatively low toxicity, and subjected to nucleophilic addition reactions, providing addition products in yields of 24 to 92%, and to cycloaddition reactions, affording cycloadducts in yields up to 80%. This work provides interesting insights into the mechanisms of aryne generation. In addition, 2-(trimethylsilyl)phenyl 4-chlorobenzenesulfonate was successfully employed in the total synthesis of (+/-)-aporphine.

Computed Properties of C7H8O2. About m-Methoxyphenol, If you have any questions, you can contact Muraca, ACA; Raminelli, C or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about O-H INSERTION; N-H; ALPHA,BETA-UNSATURATED DIAZOKETONES; ARYLATION REACTIONS; ORGANIC-SYNTHESIS; UREA; ENOLDIAZOACETAMIDES; PLATFORMS; PHENOLS, Saw an article supported by the FAPESP (Research Supporting Foundation of the State of Sao Paulo)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2017/233299, 2015/22003-7, 2019/05002-8]; CNPqConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) [303437/2015-4]; FAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2013/50228-8, 2009/54040-8]. SDS of cas: 150-19-6. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Gallo, RDC; Momo, PB; Day, DP; Burtoloso, ACB. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

The catalytic protonation of aryl diazoacetates by strong Bronsted acids, followed by a Friedel-Crafts alkylation reaction with electron rich aromatic compounds, is reported. The reaction provided in a direct fashion 24 geminal diarylacetates in yields of <= 92%. SDS of cas: 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Gallo, RDC; Momo, PB; Day, DP; Burtoloso, ACB or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Anamika; Yadav, CL; Drew, MGB; Kumar, K; Singh, N in [Anamika; Yadav, Chote Lal; Kumar, Kamlesh; Singh, Nanhai] Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 221005, Uttar Pradesh, India; [Drew, Michael G. B.] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England published Ferrocene-Functionalized Dithiocarbamate Zinc(II) Complexes as Efficient Bifunctional Catalysts for the One-Pot Synthesis of Chromene and Imidazopyrimidine Derivatives via Knoevenagel Condensation Reaction in 2021, Cited 86. SDS of cas: 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Four new mononuclear/coordination polymeric (CP) zinc(II) complexes (1-4) of ferrocenyl/pyridyl-functionalized dithiocarbamate ligands, N-ferrocenylmethyl-N-butyl dithiocarbamate (L1), N-ferrocenylmethyl-N-ethylmorpholine dithiocarbamate (L2), N-ferrocenylmethyl-N-2-(diethylamino)ethylamine dithiocarbamate (L3), and N-4-methoxybenzyl-N-3-methylpyridyl dithiocarbamate (L4), have been synthesized and characterized by elemental analyses, IR, UV-vis, and H-1 and C-13{H-1} NMR spectroscopic techniques. The solid-state structures of complexes 1, 3, and 4 have been determined by single-crystal X-ray crystallography as well as powder X-ray diffraction. Single-crystal X-ray crystallography revealed a monomeric structure for complex 1 but 1D polymeric structures for complexes 3 and 4. In all complexes, dithiocarbamate ligands are bonded to the Zn(II) metal ion in a S<^>S chelating mode, and in the CPs, N atoms on the 2-(diethylamino)ethylamine and 3-pyridyl functionalities in the ligands on the neighboring molecules are also bonded to metal centers, leading to the formation of either a discrete tetrahedral molecule in 1 or 1D CP structures in 3 and 4. The Zn(II) metal centers in the polymeric structures exhibited either square-pyramidal or octahedral geometries. The supramolecular structures in these complexes are sustained via C-H center dot center dot center dot pi (ZnCS2, chelate; 3 and 4), C-H center dot center dot center dot pi, and H center dot center dot center dot H interactions. The catalytic performances of complexes have also been assessed in the Knoevenagel condensation and one-pot multicomponent reactions. Catalysis results showed that the CP 3 acts as a heterogeneous bifunctional catalyst with excellent transformation efficiency at low catalyst loading.

SDS of cas: 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Anamika; Yadav, CL; Drew, MGB; Kumar, K; Singh, N or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O. Authors Naeimi, A; Jawhid, O; Abbaspour, S in SPRINGER published article about in [Naeimi, Atena; Jawhid, Omid] Univ Jiroft, Fac Sci, Dept Chem, Jiroft, Iran; [Jawhid, Omid] Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad, Razavi Khorasan, Iran; [Abbaspour, Sedighe] Payame Noor Univ Kerman, Dept Chem, Kerman, Iran in 2020.0, Cited 24.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Molybdenum complex was immobilized on the extracted cellulose from Palmer amaranth plant (CLCSbMo). Then, by addition of graphene oxide/ZnO bio-nanocomposite to CLCSbMo, rGO/ZnO@CLCSbMo bio-nanopolymer was produced. It was characterized by SEM, FT-IR, TGA, DTA, XRD and EDAX. Its catalytic activity was investigated on the oxidation of alcohols and corresponded aldehydes and ketones were obtained with high conversions and excellent selectivities. This heterogeneous catalyst was recycled and data were shown the high stability and durability after five runs.

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Naeimi, A; Jawhid, O; Abbaspour, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein WOS:000464767700013 published article about STRUCTURAL-CHARACTERIZATION; PROVIRAL DNA; IDENTIFICATION; INHIBITION; BINDING; RECOGNITION; COMPLEX; TAR in [Mori, Mattia; Lang, Maria Chiara Dasso; Palombi, Nastasja; Friggeri, Laura; Botta, Maurizio] Univ Siena, Dept Excellence 2018 2022, Dept Biotechnol Chem & Pharm, Via Aldo Moro 2, I-53100 Siena, Italy; [Saladini, Francesco; Giannini, Alessia; Zazzi, Maurizio] Univ Siena, Dept Med Biotechnol, Viale Mario Bracci 16, I-53100 Siena, Italy; [Kovalenko, Lesia; Mely, Yves] Univ Strasbourg, CNRS, Fac Pharm, Lab Bioimagerie & Pathol,UMR 7021, 74 Route Rhin, F-67401 Illkirch Graffenstaden, France; [De Forni, Davide; Poddesu, Barbara] ViroStat Srl, Viale Umberto I 46, I-07100 Sassari, Italy; [Malancona, Savina; Summa, Vincenzo] IRBM Sci Pk SpA, Via Pontina Km 30-600, I-00071 Pomezia, RM, Italy; [Botta, Maurizio] Temple Univ, Coll Sci & Technol, Ctr Biotechnol, Sbarro Inst Canc Res & Mol Med, BioLife Sci Bldg,Suite 333,1900 N 12th St, Philadelphia, PA 19122 USA; [Botta, Maurizio] Lead Discovery Siena Srl, Vittorio Alfieri 31, I-53019 Castelnuovo, Berardenga, Italy in 2019.0, Cited 28.0. Quality Control of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

Small molecule inhibitors of the HIV-1 nucleocapsid protein (NC) are considered as promising agents in the treatment of HIV/AIDS. In an effort to exploit the privileged 2-amino-4-phenylthiazole moiety in NC inhibition, here we conceived, synthesized, and tested in vitro 18 NC inhibitors (NCIs) bearing a double functionalization. In these NCIs, one part of the molecule is deputed to interact noncovalently with the NC hydrophobic pocket, while the second portion is designed to interact with the N-terminal domain of NC. This binding hypothesis was verified by molecular dynamics simulations, while the linkage between these two pharmacophores was found to enhance antiretroviral activity both on the wild-type virus and on HIV-1 strains with resistance to currently licensed drugs. The two most interesting compounds 6 and 13 showed no cytotoxicity, thus becoming valuable leads for further investigations.

Quality Control of 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Mori, M; Lang, MCD; Saladini, F; Palombi, N; Kovalenko, L; De Forni, D; Poddesu, B; Friggeri, L; Giannini, A; Malancona, S; Summa, V; Zazzi, M; Mely, Y; Botta, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of 3-Hydroxybenzaldehyde. Authors Khoshdel, MA; Shirini, F; Langarudi, MSN; Zabihzadeh, M; Biglari, M in ROYAL SOC CHEMISTRY published article about in [Alipour Khoshdel, Meysam; Shirini, Farhad; Nikoo Langarudi, Mohaddeseh Safarpoor; Zabihzadeh, Mehdi; Biglari, Mohammad] Univ Guilan, Dept Chem, Coll Sci, Rasht 4133519141, Iran in 2021.0, Cited 44.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

The development of environmentally benign synthetic protocols has attracted increasing attention in recent organic syntheses. As a part of this concept, our group synthesized a new natural deep eutectic solvent (NADES) by using gabapentin and choline chloride. After characterization by FTIR, H-1 and C-13 NMR, and mass spectra, the prepared NADES was utilized as an efficacious catalyst for the synthesis of 4H-pyran scaffolds such as tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone(thione) derivatives. The use of inexpensive and bio-compatible reagents for the synthesis of the catalyst, a simple and green procedure for the preparation of the catalyst and products, short reaction times, high yields of the products, and applicability to large-scale synthesis are the prominent features of this protocol. Also, the catalyst could be recovered easily and recycled up to five times without significant loss of its catalytic activity.

About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Khoshdel, MA; Shirini, F; Langarudi, MSN; Zabihzadeh, M; Biglari, M or concate me.. Safety of 3-Hydroxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles