Tag: M.W=100-150

Formula: C8H8O2. In 2021 CATAL SCI TECHNOL published article about PONNDORF-VERLEY REDUCTION; EPOXIDATION CATALYSTS; STRUCTURAL-CHARACTERIZATION; TRANSFER HYDROGENATION; OLEFIN POLYMERIZATION; QUINONE METHIDES; ACTIVE-SITES; BETA ZEOLITE; EFFICIENT; ETHERIFICATION in [Garg, Shipra; Unruh, Daniel K.; Krempner, Clemens] Texas Tech Univ, Dept Chem & Biochem, Mem Dr & Boston, Lubbock, TX 79409 USA in 2021, Cited 53. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

The polyhedral oligosilsesquioxane complexes, {[(isobutyl)(7)Si7O12]ZrOPri center dot(HOPri)}(2) (I), {[(cyclohexyl)(7)Si7O12]ZrOPri center dot(HOPri)}(2) (II), {[(isobutyl)(7)Si7O12]HfOPri center dot(HOPri)}(2) (III) and {[(cyclohexyl)(7)Si7O12]HfOPri center dot(HOPri)}(2) (IV), were synthesized in good yields from the reactions of M(OPri)(4) (M = Zr, Hf) with R-POSS(OH)(3) (R = isobutyl, cyclohexyl), resp. I-IV were characterized by H-1, C-13 and Si-29 NMR spectroscopy and their dimeric solid-state structures were confirmed by X-ray analysis. I-IV catalyze the reductive etherification of 2-hydroxy- and 4-hydroxy and 2-methoxy and 4-methoxybenzaldehyde and vanillin to their respective isopropyl ethers in isopropanol as a green solvent and reagent. I-IV are durable and robust homogeneous catalysts operating at temperatures of 100-160 degrees C for days without significant loss of catalytic activity. Likewise, I-IV selectively catalyze the conversion of 5-hydroxymethylfurfural (HMF) into 2,5-bis(isopropoxymethyl)furane (BPMF), a potentially high-performance fuel additive. Similar results were achieved by using a combination of M(OPri)(4) and ligand R-POSS(OH)(3) as a catalyst system demonstrating the potential of this in situ approach for applications in biomass transformations. A tentative reaction mechanism for the reductive etherification of aldehydes catalysed by I-IV is proposed.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Garg, S; Unruh, DK; Krempner, C or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 80-59-1. Recently I am researching about BIOGENIC SYNTHESIS; ENHANCED ANTIBACTERIAL; MALACHITE GREEN; LEAF EXTRACT; ANTIOXIDANT; DEGRADATION; REDUCTION, Saw an article supported by the . Published in SPRINGER HEIDELBERG in HEIDELBERG ,Authors: Jaffri, SB; Ahmad, KS. The CAS is 80-59-1. Through research, I have a further understanding and discovery of (E)-2-Methylbut-2-enoic acid

Silver nanoparticles were fabricated in the presence and absence of light with silver nitrate and aqueous extract of Prunus cerasifera leaf via facile and one-pot green method. P. cerasifera leaf extract reduced and stabilized the nanoparticles with phytometabolites expunging the need for addition of external reducing agents. Optimized silver nanoparticle syntheses was done with variations in leaf extract concentration, time, temperature, and molarity for deciphering the photocatalytic, antifungal, and antibacterial potential of synthesized nanoparticles. Optical, compositional, and morphological analyses of the synthesized nanoparticles were done by UV-visible spectrometry (UV-Vis), Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy (SEM), and X-ray diffraction (XRD). Formation of silver nanoparticles was confirmed firstly through UV-Vis by exhibition of peaks with 400-450 nm. FTIR confirmed the presence of major organic groups responsible for reduction of nanoparticles. AFM confirmed the spherical morphology of the synthesized nanoparticles with remarkable dispersion without any agglomeration. Phytochemical analysis for P. cerasifera leaf metabolites was done by GC-MS. Spherical nanoparticles having a size range of 57-144 nm were obtained with face-centered cubic crystals. The average crystallite size obtained from XRD spectra was 2.34 nm. Enhanced photocatalytic first-order kinetics were obtained for persistent organic pollutants, i.e., crystal violet, methylene blue, and malachite green (R-2 = 0.99, 0.99, 0.98) in less than 15 min. Biomedical and agricultural significance as an antibiotic drug and utilization as a fungicides substitute was explored against nine resistant microbes. Statistically significant variations were analyzed via one-way analysis of variance (ANOVA) and Kruskal-Wallis test and specific multi comparison tests. Active to highly active inhibition zones manifested the use of biogenic silver nanoparticles as potential candidate for applications in biological arenas and as environmental remediators.

About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Jaffri, SB; Ahmad, KS or concate me.. Recommanded Product: 80-59-1

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article An approach for the calculation of vaporization enthalpies of aromatic and heteroaromatic compounds at 298.15 K applicable to supercooled liquids WOS:000583948500144 published article about STANDARD MOLAR ENTHALPIES; NORMAL BOILING TEMPERATURE; VAPOR-PRESSURES; THERMODYNAMIC PROPERTIES; HEAT-CAPACITIES; THERMOCHEMICAL PROPERTIES; SUBLIMATION ENTHALPIES; PHASE-TRANSITIONS; ORGANIC-COMPOUNDS; SUBSTITUTED BENZENES in [Solomonov, Boris N.; Yagofarov, Mikhail, I] Kazan Fed Univ, Dept Phys Chem, Kremlevskaya Str 18, Kazan 420008, Russia in 2020, Cited 186. Recommanded Product: m-Methoxyphenol. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6

An approach for the calculation of the vaporization enthalpies of aromatic and heteroaromatic compounds at T = 298.15 K with accuracy competitive with experiment was proposed. The vaporization enthalpies may be calculated from the solution enthalpies of liquid and solvation enthalpies in benzene. The solution enthalpies of liquids were shown to be constant within a given type of aromatic compounds. For a set of 67 liquid and 41 solid aromatic and heteroaromatic compounds not capable of intermolecular hydrogen bonding, it was experimentally demonstrated that the solution enthalpies of liquids or supercooled liquids in benzene were equal to 1 +/- 1 kJ . mol(-1). The way to consider intermolecular hydrogen bonding, e.g., in phenol, aniline, pyrrole derivatives, was also proposed. The methods for solvation enthalpy calculation were proposed previously. The calculated and literature vaporization enthalpies values of 415 aromatic and heteroaromatic compounds were compared. Average absolute deviation amounted to 1.3 kJ . mol(-1). The proposed approach is especially valuable for calculation of the vaporization enthalpies of low-volatile compounds, including those solid at T = 298.15 K. (C) 2020 Elsevier B.V. All rights reserved.

About m-Methoxyphenol, If you have any questions, you can contact Solomonov, BN; Yagofarov, MI or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 4′-Hydroxyacetophenone. Jeong, J; Kim, KH; Kim, DY; Chandrasekaran, G; Kim, M; Pagire, SH; Dighe, M; Choi, EY; Bak, SM; Kim, EY; Shin, MG; Choi, SY; Ahn, JH in [Jeong, Jieun; Kim, Minhee; Pagire, Suvarna H.; Dighe, Mahesh; Ahn, Jin Hee] Gwangju Inst Sci & Technol, Dept Chem, Gwangju 61005, South Korea; [Kim, Kun-Hee; Chandrasekaran, Gopalakrishnan; Choi, Seok-Yong] Chonnam Natl Univ, Dept Biomed Sci, Med Sch, Gwangju, South Korea; [Kim, Dong-Young] Univ Ulsan, Coll Med, Dept Biomed Sci, Seoul, South Korea; [Bak, Su-Min; Kim, Eun-Young] Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul, South Korea; [Bak, Su-Min; Kim, Eun-Young] Kyung Hee Univ, Dept Biol, Seoul, South Korea; [Shin, Myung-Geun] Chonnam Natl Univ, Dept Lab Med, Med Sch, Gwangju, South Korea published Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model in 2019.0, Cited 18.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A new series of 1,3-diketone, heterocyclic and alpha, beta-unsaturated derivatives were synthesized and evaluated for their AhR antagonist activity using zebrafish and mammalian cells. Compounds 1b, 2c, 3b and 5b showed significant AhR antagonist activity in a transgenic zebrafish model. Among them, compound 3b, and 5b were found to have excellent AhR antagonist activity with IC50 of 3.36 nM and 8.3 nM in a luciferase reporter gene assay. In stem cell proliferation assay, compound 5b elicited marked HSC expansion.

Quality Control of 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Jeong, J; Kim, KH; Kim, DY; Chandrasekaran, G; Kim, M; Pagire, SH; Dighe, M; Choi, EY; Bak, SM; Kim, EY; Shin, MG; Choi, SY; Ahn, JH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Physico-chemical characterization of carbonized apricot kernel shell as precursor for activated carbon preparation in clean technology utilization WOS:000483414000072 published article about HEAVY-METAL IONS; SORPTIVE PROPERTIES; FTIR SPECTROSCOPY; WASTE BIOMASS; SURFACE-AREA; BIOCHAR; ADSORPTION; REMOVAL; PYROLYSIS; ADSORBENT in [Jankovic, Bojan; Pijovic, Milena; Katnic, Durica; Tasic, Gvozden] Univ Belgrade, Dept Phys Chem, Inst Nucl Sci Vinca, Mike Petrovica Alasa 12-14,POB 522, Belgrade 11001, Serbia; [Manic, Nebojsa] Univ Belgrade, Fuel & Combust Lab, Fac Mech Engn, Kraljice Marije 16,POB 35, Belgrade 11120, Serbia; [Dodevski, Vladimir; Radovic, Ivana] Univ Belgrade, Mat Sci Lab, Inst Nucl Sci Vinca, Mike Petrovica Alasa 12-14,POB 522, Belgrade 11001, Serbia in 2019.0, Cited 74.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Category: indole-building-block

This paper investigates the ability of waste apricot (Prunus armeniaca) kernel shells (AKS) bio-char prepared by single-step carbonization process at 850 degrees C (residence time of 1 h) for possible removal of toxic elements and organic micro-pollutants. The experiment that was performed as well as parameters used proved to be optimal for bio-char production as adsorbing medium, where last issue is validated by multiform material characterization techniques. It has been shown that the produced bio-char possess highly-porous morphology features, with large specific surface area (328.570 m(2) g(-1)). The obtained product was characterized by various pore sizes (including super-micropores and mesopores with maximum pore size of 2.24 nm) structures. Preliminary results are indicated that obtained bio-char can shows increased affinity to possible adsorption of the small organic molecule contaminants upgraded by its physico-chemical properties. Cost estimation of AKS bio-char production substantiated its cost effectiveness and its good physical and chemical properties for future design in batch adsorption and regeneration tests. It was established that AKS produced bio-char was 2.5 times cheaper than the commercially available activated carbon. Bio-char exhibits promising removal performances for potential adsorption of heavy metal and organic micro-pollutants from wastewaters systems, as indicated by material textures and spectroscopy measurements. (C) 2019 Elsevier Ltd. All rights reserved.

Category: indole-building-block. About Benzyl Alcohol, If you have any questions, you can contact Jankovic, B; Manic, N; Dodevski, V; Radovic, I; Pijovic, M; Katnic, D; Tasic, G or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sugimoto, K; Kosuge, S; Sugita, T; Miura, Y; Tsuge, K; Matsuya, Y in [Sugimoto, Kenji; Kosuge, Shuto; Sugita, Takae; Miura, Yuka; Matsuya, Yuji] Univ Toyama, Fac Pharmaceut Sci, Toyama 9300194, Japan; [Tsuge, Kiyoshi] Univ Toyama, Fac Sci, Toyama 9308555, Japan published Au(I) Catalyzed Synthesis of Densely Substituted Pyrazolines and Dihydropyridines via Sequential Aza-Enyne Metathesis/6 pi-Electrocyclization in 2021.0, Cited 34.0. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A gold(I) autotandem catalysis protocol is reported for the de novo synthesis of densely substituted pyrazolines and dihydropyridines from the corresponding imine derivatives in a highly regioselective fashion via a one-pot aza-enyne metathesis/6 pi-electrocyclization sequence. The substituents on the nitrogen atom of the imine perfectly control the reaction pathways from the pivotal 1-azabutadiene intermediate; thus, carbazates were converted into pyrazolines via 6 pi-electrocyclization of alpha,beta-unsaturated hydrazones, while aryl imines provided dihydropyridines via 6 pi-electrocyclization of 3-azahexatrienes.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Sugimoto, K; Kosuge, S; Sugita, T; Miura, Y; Tsuge, K; Matsuya, Y or concate me.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 3-Hydroxybenzaldehyde. Recently I am researching about NITRIC-OXIDE SYNTHASE; 2-BENZOYL-6-BENZYLIDENECYCLOHEXANONE ANALOGS; CURCUMIN; INHIBITION; GENERATION; DESIGN; SERIES, Saw an article supported by the Ministry of Higher Education (MOHE) of Malaysia [FRGS/1/2014/ST01/UPM/02/1 (5538011)]. Published in SPRINGER BIRKHAUSER in NEW YORK ,Authors: Leong, SW; Awin, T; Faudzi, SMM; Maulidiani, M; Shaari, K; Abas, F. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde

A series of seven new (1, 3, 6, 7, 10, 12, and 13) and six (2, 4, 5, 8, 9, and 11) known diarylpentanoid analogs were synthesized and assessed for their nitric oxide (NO) and alpha-glucosidase inhibitory activities as well as their antioxidant capacity. Nine compounds (2, 3, 4, 5, 6, 8, 11, 12, and 13) were found to exhibit comparable activity to that of curcumin (IC50 = 13.0 mu M), in which compound 8 has displayed strongest NO inhibitory activity with the IC50 values of 17.5 mu M. Meanwhile, four compounds (1, 7, 12, and 13) were found to possess better alpha-glucosidase inhibitory activity than that of curcumin (30.9 mu M), with the IC50 values ranging from 19.4 to 24.9 mu M. On the other hand, none of the synthesized compounds has achieved better DPPH scavenging activities than that of curcumin, indicating the relatively poor antioxidant potential of desired diarylpentanoid structure. Structure-activity relationship (SAR) study disclosed that the existence of meta-hydroxyphenyl and bromo groups is crucial for antiinflammatory and anti-alpha-glucosidase activities, respectively. Molecular docking study showed that bromo moiety could form additional hydrophobic contacts with alpha-glucosidase, thereby increased the inhibition of diarylpentanoid against alpha-glucosidase. The overall results suggested that diarylpentanoids with poly-meta-hydroxylated phenyl ring and multiple bromo groups may lead to the discovery of new diarylpentanoids with both antiinflammatory and anti-alpha-glucosidase activities.

Recommanded Product: 3-Hydroxybenzaldehyde. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Leong, SW; Awin, T; Faudzi, SMM; Maulidiani, M; Shaari, K; Abas, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Category: indole-building-block. Kapoor, G; Pathak, DP; Bhutani, R; Husain, A; Jain, S; Iqbal, MA in [Kapoor, Garima; Pathak, Dharam Pal; Bhutani, Rubina] Delhi Inst Pharmaceut Sci & Res, Dept Pharmaceut Chem, New Delhi 110017, India; [Husain, Asif; Iqbal, Md. Azhar] Hamdard Univ, Jamia Hamdard, Fac Pharm, Dept Pharmaceut Chem, New Delhi, India; [Jain, Sandeep] Guru Jambeshwar Univ Sci & Technol, Dept Pharmaceut Chem, Hisar, Haryana, India published Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid in 2019.0, Cited 40.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

A new series of octadec-9-enoic acid schiff base entities (S1-S30) were designed and synthesized targeting peroxisome proliferator activated receptor-gamma for agonist action. Molinspiration software (online) was used to estimate drug like molecular properties of the metabolites. Docking disquisition on co-crystallized protein of PPAR-gamma (PDB ID 1FM9) was carried out which showed S21, S10 and S7 as best situated in the vital sites of receptor having docking scores – 9.19, – 8.68 and – 8.64 respectively. Free binding energy measured using model of Maestro 9.0 and was in range of from – 40.01 and – 80.54 kcal/mol, significant when compared with pioglitazone (- 51.58 Kcal/mol). Seven best docked derivatives were assessed for in-vivo oral glucose tolerance on normal rats and anti-hyperglycaemic activity by streptozotocin induced diabetes model. S21 unveiled to be the best measured analogue among all the synthesized entities. Encouraging outcomes motivates fatty acids for further development of more effective and safer compounds.

Category: indole-building-block. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Kapoor, G; Pathak, DP; Bhutani, R; Husain, A; Jain, S; Iqbal, MA or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article The Catalytic Regio- and Stereoselective Synthesis of 1,6-Diazabicyclo[4.3.0]nonane-2,7-diones WOS:000670661000006 published article about ASYMMETRIC 1,3-DIPOLAR CYCLOADDITIONS; MELDRUMS ACID; MULTICOMPONENT SYNTHESIS; AZOMETHINE IMINES; ANNULATION; CHEMISTRY; YLIDES in [Lebrene, Arthur; Martzel, Thomas; Gouriou, Laura; Levacher, Vincent; Oudeyer, Sylvain; Afonso, Carlos; Loutelier-Bourhis, Corinne; Briere, Jean-Francois] Normandie Univ, COBRA, CNRS, INSA Rouen,UNIROUEN, F-76000 Rouen, France; [Sanselme, Morgane] Univ Rouen, Normandie Univ, Lab SMS, EA3233, F-76821 Mont St Aignan, France in 2021, Cited 37. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. Name: 4-Methoxybenzaldehyde

A straightforward synthesis of original 1,6-diazabicyclo[4.3.0]nonane-2,7-diones was achieved through a DBU-organocatalyzed multicomponent Knoevenagel-aza-Michael-Cyclocondensation reaction which takes advantage of an unprecedented highly regio- and diastereoselective conjugate addition of pyridazinones to alkylidene Meldrum’s acid intermediates. The key reactive intermediates of this complex process were analyzed by means of electrospray ionization mass spectrometry coupled to ion mobility spectrometry, allowing us to validate the proposed mechanism.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Lebrene, A; Martzel, T; Gouriou, L; Sanselme, M; Levacher, V; Oudeyer, S; Afonso, C; Loutelier-Bourhis, C; Briere, JF or concate me.. Name: 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 80-59-1. Recently I am researching about ACETIC-ANHYDRIDE; ORGANIC HALIDES; ARYL BROMIDES; OLEFINS; CO; HYDROCARBOXYLATION; HYDROXYCARBONYLATION; ALKYNES; HYDROESTERIFICATION, Saw an article supported by the European UnionEuropean Commission; European Social FundEuropean Social Fund (ESF) [EFOP-3.6.1.-16-2016- 00004]; Ministry of Human Capacities [ONKP-17-4-II]; [GINOP-2.3.2-15-2016-00049]; [OTKAK113177]. Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Bartal, B; Mikle, G; Kollar, L; Pongracz, P. The CAS is 80-59-1. Through research, I have a further understanding and discovery of (E)-2-Methylbut-2-enoic acid

Palladium-catalysed carbonylation reactions have been developed in the presence of formic acid as carbon monoxide source. alpha,beta-Unsaturated carboxylic acids and esters were synthesized by the transformation of alkenyl halides in moderate to good yields. The selection of the base proved to be crucial regarding the reaction outcome. A set of various substrates were proven under optimised reaction conditions. Compared to aliphatic alcohols, phenols showed excellent reactivity as O-nucleophiles.

SDS of cas: 80-59-1. About (E)-2-Methylbut-2-enoic acid, If you have any questions, you can contact Bartal, B; Mikle, G; Kollar, L; Pongracz, P or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles