Tag: M.W=100-150

Recently I am researching about AQUEOUS OXIDATIONS; COUPLING REACTIONS; IONIC LIQUIDS; PALLADIUM; DERIVATIVES; ALCOHOLS; ACID; NANOCOMPOSITE; CYCLIZATION; DESIGN, Saw an article supported by the University of Birjand. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Siuki, HK; Bagherzade, G; Kargar, PG. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol. Computed Properties of C7H8O

In this paper, the properties of a catalyst that composed of magnetic nanoparticles and Pectin biopolymer that is widely found in nature (Fe3O4@Pectin) to support nickel (II) acetate are discussed, and this catalyst was then used in response to the synthesis of the precursor required for xanthene synthesis. The heterogeneous catalyst was characterized by techniques such as FT-IR spectroscopy, FE-SEM, TEM, XRD spectroscopy, EDX spectroscopy, VSM, and ICP spectroscopy. Thermal gravimetric analysis (TGA) was also used to determine the thermal stability of the material techniques. Then the catalyst was explored in the oxidation reaction of alcohols that has high efficiency and selectivity and the synthesized aldehydes were used as precursors for the synthesis of xanthans. Xanthans are important compounds found in a variety of biological components and drugs. The most important advantages of this method are easy to work up procedure, perform the reaction in solvent-free conditions, and the catalyst can be separated by an external magnet and used several times without reducing the activity.

Computed Properties of C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Siuki, HK; Bagherzade, G; Kargar, PG or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H8O. Recently I am researching about LIQUID-PHASE OXIDATION; FREE SELECTIVE OXIDATION; SOLVENT-FREE OXIDATION; H BOND ACTIVATION; CATALYTIC-OXIDATION; SPECTROSCOPIC CHARACTERIZATION; MOLECULAR-OXYGEN; SURFACE; MANGANESE; COMPLEX, Saw an article supported by the National Key Research and Development Program of China [2016YFA0602900]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21938001, 21878344]; National Natural Science Foundation of China-SINOPEC Joint Fund [U1663220]; Guangdong Provincial Key RD Programme [2019B110206002]; Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program [2017BT01C102]; Research and Innovation Team Construction Project of Guangdong University of Petrochemical Technology. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Zhou, XT; Chen, HY; Han, Q; Lv, M; Ji, HB. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

The activation of dioxygen is the major challenge in the catalytic oxygenation of hydrocarbons under mild conditions. In this study, the catalytic efficiency for the aerobic oxidation of toluene and its derivatives by using cobaltmeso-tetraphenylporphyrin was enhanced by using acetylacetone as the oxygen activator. The influences of reaction conditions such as solvent, different metalloporphyrin catalysts, temperature, pressure and acetylacetone loading were studied, as well as the kinetics of the oxidation. Various toluene derivatives could also be oxidized to the corresponding products in satisfactory yields with this catalytic system. Based on the characterization ofin situelectron paramagnetic resonance (EPR) andin situUV-vis spectroscopy, the catalytic mechanism was also proposed, in which acetylacetone served as the key initiator of the free radical in activating dioxygen.

Computed Properties of C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Zhou, XT; Chen, HY; Han, Q; Lv, M; Ji, HB or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry; Science & Technology – Other Topics; Materials Science very interesting. Saw the article Unraveling Kinetic Effects during Photoelectrochemical Mineralization of Phenols. Rutile:Anatase TiO2 Nanotube Photoanodes under Thin-Layer Conditions published in 2021.0. SDS of cas: 150-76-5, Reprint Addresses Vargas, R (corresponding author), Univ Simon Bolivar USB, Dept Quim, Caracas 1080, Venezuela.; Vargas, R (corresponding author), Univ Nacl San Martin UNSAM, CONICET, Inst Tecnol Chascomus INTECH, B7130IWA, Chascomus, Argentina.. The CAS is 150-76-5. Through research, I have a further understanding and discovery of Mequinol

The kinetics of the photoelectrochemical mineralization of p-nitrophenol (PNP) and p-methoxyphenol (PMP) on rutile:anatase TiO2 nanotube electrodes (% rutile: 0, 16, and 20) has been studied. Oxidative photocurrent enhances with the increase of both the electrode potential and the rutile content. Time-resolved photoluminescence measurements reveal that incorporation of rutile into anatase nanotubes has effects on recombination dynamics. From measurements of electrical charge as a function of time under thin-layer conditions under potentiostatic control, it was determined that the oxidation of PNP and PMP follows the apparent Langmuir-Hinshelwood rate law. Chemical oxygen demand measurements confirmed total oxidation. The reaction rate parameters that define the kinetic constant (k) due to the reaction of hydroxyl radicals with adsorbed phenols and the thermodynamic constant (K) due to the adsorption of phenols with the electrode surface have been decoupled. The interaction of PNP with the surface of all TiO2 electrodes is highly favored, K(PNP) > K(PMP), resulting in a surface concentration of PNP considerably higher than that of PMP. The specific rate of the surface reaction for the transformation of phenols also increases, but the trend is inverse, that is, for all electrodes, k(PMP) > k(PNP). Understanding these kinetic tendencies can lead to better transformation of light in redox reactions.

About Mequinol, If you have any questions, you can contact Leon, D; Maimone, A; Carvajal, D; Madriz, L; Scharifker, BR; Cabrerizo, FM; Vargas, R or concate me.. SDS of cas: 150-76-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Manickam, M; Pichaimani, P; Arumugam, H; Muthukaruppan, A in [Manickam, Manoj; Pichaimani, Prabunathan; Arumugam, Hariharan; Muthukaruppan, Alagar] PSG Inst Technol & Appl Res, Polymer Engn Lab, Coimbatore 641062, Tamil Nadu, India published Synthesis of Nontoxic Pyrazolidine-Based Benzoxazine-Coated Cotton Fabric for Oil-Water Separation in 2019.0, Cited 37.0. HPLC of Formula: C8H8O2. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

In the present work, pyrazolidine bisphenol (PYBP)-based superhydrophobic/superoleophilic benzoxazine (PBz) matrices were synthesized and described in comparison with bisphenol F benzoxazines. The preliminary in vitro toxicity assay reveals the nontoxic nature of PYBP. Data obtained from thermal and surface studies indicate that the prepared PYBP-based PBzs have enhanced thermal stability than those of bisphenol F benzoxazines. Further, the prepared PYBP-based PBz-coated cotton fabric displayed superior water contact angle (WCA = 154.7 degrees) and sliding contact angle (theta = 9 degrees). Observations from SEM images suggest that the inherent superhydrophobic nature was due to the formation of rough surfaces. Furthermore, oil-water separation was successfully ascertained from the appropriate experimental conditions using the PYBP-coated fabric. The separation efficiency and flux are found to be greater than 90% after 10 cycles. Thus, the PYBP-based superhydrophobic/superoleophilic polybenzoxazines (PBzs) have been synthesized and characterized to assess their suitability for water-repellent and oil-water separation applications.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Manickam, M; Pichaimani, P; Arumugam, H; Muthukaruppan, A or concate me.. HPLC of Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 3-Hydroxybenzaldehyde. I found the field of Energy & Fuels; Engineering very interesting. Saw the article Nontarget Analysis of Oxygenates in Catalytic Fast Pyrolysis Biocrudes by Supercritical Fluid Chromatography High-Resolution Mass Spectrometry published in 2019.0, Reprint Addresses Christensen, JH (corresponding author), Univ Copenhagen, Fac Sci, Dept Plant & Environm Sci, Thorvaldsensvej 40, DK-1871 Frederiksberg, Denmark.. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde.

Catalytic fast pyrolysis (CFP) biocrudes can comprise up to 30 wt % of oxygen content in compounds such as polyphenols, acids, carbonyls, and anhydrosugars and thus require upgrading by, e.g., hydrotreatment, to produce transport fuels. The chemical characterization of phenolic and acidic compounds in biocrudes is of great importance to optimize the CFP process. In this study, an analytical workflow is proposed for nontarget chemical fingerprinting analysis of CFP biocrudes using supercritical fluid chromatography high-resolution mass spectrometry (SFC-HRMS) with negative electrospray ionization (ESI-), followed by multivariate data analysis. The method was developed and tested on five biocrude samples from loblolly pine (Pinus taeda) with varying oxygen content (14.9-28.8 wt % wet basis) due to different CFP conditions. The pixel-based analysis displayed chemical variation between all samples. Twenty-four regions of interest were tentatively identified, including mono- and polyphenols, fatty acids, and methylated and methoxylated phenols. The identification workflow and MS/MS analysis were prioritized on the peaks with the highest relative concentration. The developed SFC-ESI–HRMS method shows high repeatability and analyzed oxygen-containing compounds with hydroxyl and/or carboxyl moieties in combination with other moieties of up to 400 Da.

About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Lubeck, JS; Tomasi, G; Poulsen, KG; Mante, OD; Dayton, DC; Verdier, S; Christensen, JH or concate me.. Application In Synthesis of 3-Hydroxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins WOS:000558066500020 published article about RESISTANT PROSTATE-CANCER; ANDROGEN RECEPTOR; DIHYDROTESTOSTERONE; TARGET; INHIBITORS; ANDROSTANEDIOL; DEHYDROGENASES; IDENTIFICATION; TESTOSTERONE; BIOCHEMISTRY in [Sviripa, Vitaliy M.; Williams, Alexander H.; Zhan, Chang-Guo] Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA; [Sviripa, Vitaliy M.; Begley, Kristin L.; Wyrebek, Przemyslaw; Kril, Liliia M.; Balia, Andrii G.; Zhan, Chang-Guo; Watt, David S.] Univ Kentucky, Coll Pharm, Ctr Pharmaceut Res & Innovat, Lexington, KY 40536 USA; [Sviripa, Vitaliy M.; Liu, Chunming; Watt, David S.] Univ Kentucky, Lucille Parker Markey Canc Ctr, Lexington, KY 40536 USA; [Fiandalo, Michael, V; Mohler, James L.] Roswell Pk Comprehens Canc Ctr, Dept Expt Therapeut, Buffalo, NY 14263 USA; [Begley, Kristin L.; Wyrebek, Przemyslaw; Kril, Liliia M.; Balia, Andrii G.; Liu, Chunming; Watt, David S.] Univ Kentucky, Coll Med, Dept Mol & Cellular Biochem, Lexington, KY 40536 USA; [Parkin, Sean R.] Univ Kentucky, Coll Arts & Sci, Dept Chem, Lexington, KY 40506 USA; [Subramanian, Vivekanandan] Univ Kentucky, Coll Pharm, NMR Ctr, Lexington, KY 40536 USA; [Chen, Xi] South Cent Univ Nationalities, Coll Chem & Mat Sci, Wuhan 430074, Peoples R China; [Mohler, James L.] Roswell Pk Comprehens Canc Ctr, Dept Urol, Buffalo, NY 14263 USA in 2020.0, Cited 57.0. The Name is m-Methoxyphenol. Through research, I have a further understanding and discovery of 150-19-6. Product Details of 150-19-6

Androgen-deprivation therapy (ADT) is only a palliative measure, and prostate cancer invariably recurs in a lethal, castration-resistant form (CRPC). Prostate cancer resists ADT by metabolizing weak, adrenal androgens to growth-promoting 5 alpha-dihydrotestosterone (DHT), the preferred ligand for the androgen receptor (AR). Developing small-molecule inhibitors for the final steps in androgen metabolic pathways that utilize 17-oxidoreductases required probes that possess fluorescent groups at C-3 and intact, naturally occurring functionality at C-17. Application of the Pictet-Spengler condensation to substituted 4-(2-aminoethyl)coumarins and 5 alpha-androstane-3-ones furnished spirocyclic, fluorescent androgens at the desired C-3 position. Condensations required the presence of activating C-7 amino orN,N-dialkylamino groups in the 4-(2-aminoethyl)coumarin component of these condensation reactions. Successful Pictet-Spengler condensation, for example, of DHT with 9-(2-aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one led to a spirocyclic androgen, (3R,5S,10S,13S,17S)-17-hydroxy-10,13-dimethyl-1,2,2 ‘,3 ‘,4,5,6,7,8,8 ‘,9,9 ‘,10,11,12,12 ‘,13,13 ‘,14,15,16,17-docosahydro-7 ‘ H,11 ‘ H-spiro-[cyclopenta[a]phenanthrene-3,4 ‘-pyrido[3,2,1-ij]pyrido[4 ‘,3 ‘:4,5]pyrano[2,3-f]quinolin]-5 ‘(1 ‘ H)-one. Computational modeling supported the surrogacy of the C-3 fluorescent DHT analog as a tool to study 17-oxidoreductases for intracrine, androgen metabolism.

Product Details of 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Sviripa, VM; Fiandalo, MV; Begley, KL; Wyrebek, P; Kril, LM; Balia, AG; Parkin, SR; Subramanian, V; Chen, X; Williams, AH; Zhan, CG; Liu, CM; Mohler, JL; Watt, DS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis, in vitro evaluation and molecular docking of new pyrazole derivatives bearing 1,5,10,10a-tetrahydrobenzo[g]quinoline-3-carbonitrile moiety as potent antibacterial agents WOS:000580977100002 published article about ANTIMICROBIAL ACTIVITY; ANALGESIC ACTIVITY; HETEROCYCLES in [Elkanzi, Nadia A. A.; Alruwaili, May M.; Alruwaili, Enas D.; Almamtrfi, Rahaf W.; Alsharary, Hadeel Kh.] Jouf Univ, Coll Sci, Chem Dept, POB 2014, Sakaka, Saudi Arabia; [Elkanzi, Nadia A. A.] Aswan Univ, Fac Sci, Chem Dept, POB 81528, Aswan, Egypt; [Hrichi, Hajer] Carthage Univ, Ctr Urbain Nord, Natl Inst Appl Sci & Technol, BPN 676, Tunis 1080, Tunisia; [Bakr, Rania B.; Hendawy, O.] Jouf Univ, Coll Pharm, Dept Pharmacol, Sakaka 2014, Aljouf, Saudi Arabia; [Bakr, Rania B.] Beni Suef Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Bani Suwayf 62514, Egypt; [Hendawy, O.] Beni Suef Univ, Fac Med, Dept Clin Pharmacol, Bani Suwayf, Egypt in 2021, Cited 34. Product Details of 123-11-5. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

In the current study, a new series of pyrazole derivatives4a-d,5a-dand6a-dpossessing 1,5,10,10a-tetrahydrobenzo[g]quinoline-3-carbonitrile moiety were synthesized by treating chalcones (3a-d) with hydrazine monohydrate/acetic anhydride, hydrazine monohydrate/formic acid and 4-chlorophenylhydrazine in ethanol, respectively. These reactions proceeded smoothly with satisfactory yields, and the obtained compounds were characterized using FTIR,H-1-NMR,C-13-NMR and elemental analyses. All the synthesized compounds were subjected to antibacterial activity againstBacillus subtilis,Staphylococcus aureus,Escherichia coli, andPseudomonas aeruginosabacteria and molecular docking studies. The antibacterial studies showed that all compounds exhibited good to excellent antibacterial activity against the tested bacterial strains. The structure-activity relationship studies revealed that the compounds3b,4b,5band6bbearing a chlorine atom at the para position of the phenyl group attached to pyrazole moiety in displayed the highest antibacterial activity against all the tested bacteria exceeding the standard drug ampicillin. Moreover, the molecular docking results showed that the highest scores docking have been obtained from the most active antibacterial compounds3b,3d,4b,4d,4c,5band6bwith good energy binding score within the active site of topoisomerase II DNA gyrase enzymes (PDB ID: 2XCS), suggesting that they can act by the inhibition of DNA replication. These compounds are auspicious candidates as antibacterial agents that would deserve further investigations.

Product Details of 123-11-5. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Elkanzi, NAA; Hrichi, H; Bakr, RB; Hendawy, O; Alruwaili, MM; Alruwaili, ED; Almamtrfi, RW; Alsharary, HK or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C7H8O. I found the field of Chemistry; Materials Science very interesting. Saw the article Facile synthesis of hydrothermally stable mesoporous ZSM-5 zeolite from Al- SBA-16 via steam assisted crystallization published in 2020, Reprint Addresses Cheralathan, KK (corresponding author), VIT, Sch Adv Sci, Dept Chem, Vellore 632014, Tamil Nadu, India.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol.

In this work, Al grafted SBA-16 (Al-SBA-16) is converted into a fully crystalline hierarchical mesoporous ZSM-5 zeolite with hydrothermal stability by steam assisted crystallization under controlled conditions. The secondary mesoporosity is due to reorganization and recrystallization events happening upon steaming the precursor. Two mesoporous aluminosilicates (Al-SBA-16s) are used as the precursors of zeolites. The precursors are obtained by post-synthetic Al grafting on the silica walls of SBA-16 with aluminium isopropoxide and sodium aluminate. Mesoporous ZSM-5 zeolites obtained from the Al-SBA-16 precursors and commercial ZSM-5 are characterized using XRD, XRF, FT-IR, TEM, N-2 adsorption, Al-27 and Si-29 MAS NMR, and TPD of NH3. The results indicated the presence of intraparticle mesoporosity in the prepared mesoporous zeolites and they have comparable crystallinity with commercial ZSM-5. Catalytic activity of the synthesized mesoporous zeolites in benzylation of mesitylene is found to be comparatively more than commercial ZSM-5, which shows existence of micro/meso hierarchical structure in the mesoporous ZSM-5 zeolites. The aluminium sources, aluminium isopropoxide and sodium aluminate have a remarkable influence on the textural, acidity, and hydrothermal stability characteristics of the synthesized mesoporous ZSM-5 zeolites.

About Benzyl Alcohol, If you have any questions, you can contact Kamil, MSM; Cheralathan, KK or concate me.. Formula: C7H8O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H8O2. Authors Shen, J; Li, QW; Zhang, XY; Wang, X; Li, GZ; Li, WZ; Yang, SD; Yang, B in AMER CHEMICAL SOC published article about in [Shen, Jian; Li, Qi-Wei; Zhang, Xin-Yue; Wang, Xue; Li, Gui-Zhi; Li, Wen-Zuo; Yang, Bin] Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China; [Yang, Shang-Dong] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China in 2021, Cited 112. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

A Tf2O/DMSO-based system for the dehydrogenative coupling of a wide range of alcohols, phenols, thiols, and thiophenols with diverse phosphorus reagents has been developed. This metal- and strong-oxidant-free strategy provides a facile approach to a great variety of organophosphinates and thiophosphates. The simple reaction system, good functional-group tolerance, and broad substrate scope enable the application of this method to the modification of natural products and the direct synthesis of bioactive molecules and flame retardants.

Computed Properties of C7H8O2. About Mequinol, If you have any questions, you can contact Shen, J; Li, QW; Zhang, XY; Wang, X; Li, GZ; Li, WZ; Yang, SD; Yang, B or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article A new antifungal aminobenzamide derivative from the endophytic fungus Fusarium sp. WOS:000468924000005 published article about TETRACYCLIC TRITERPENOIDS; FUSARITHIOAMIDE; BUTYROLACTONES in [Ibrahim, Sabrin R. M.; Al Haidari, Rwaida A.; Zayed, Mohamed F.] Taibah Univ, Coll Pharm, Dept Pharmacognosy & Pharmaceut Chem, Al Madinah Al Munawwarah, Saudi Arabia; [Ibrahim, Sabrin R. M.] Assiut Univ, Fac Pharm, Dept Pharmacognosy, Assiut, Egypt; [Mohamed, Gamal A.] King Abdulaziz Univ, Fac Pharm, Dept Nat Prod & Alternat Med, Jeddah, Saudi Arabia; [Mohamed, Gamal A.] Al Azhar Univ, Assiut Branch, Fac Pharm, Dept Pharmacognosy, Assiut, Egypt; [Khayat, Maan T.] King Abdulaziz Univ, Fac Pharm, Dept Pharmaceut Chem, Jeddah, Saudi Arabia; [El-Kholy, Amal A.] Taibah Univ, Coll Pharm, Dept Clin & Hosp Pharm, Al Madinah Al Munawwarah, Saudi Arabia; [El-Kholy, Amal A.] Ain Shams Univ, Dept Clin Pharm, Fac Pharm, Cairo, Egypt; [Zayed, Mohamed F.] Al Azhar Univ, Dept Pharmaceut Chem, Fac Pharm, Cairo, Egypt in 2019.0, Cited 17.0. Quality Control of 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

Background: Endophytic fungi attracted attention as a prolific source of bioactive natural products with a potent pharmaceutical activity and unique structure. Objective: The main goal of the study is to separate and identify the bioactive constituents from the endophytic fungus Fusarium sp. as well as to evaluate the antimicrobial of the new metabolites. Materials and Methods: The fungus was cultured on a rice medium, and then, the cultures were extracted with ethyl acetate (EtOAc). The EtOAc extract was chromatographed utilizing different chromatographic methods to give five metabolites. The structural determination of these metabolites was carried out by the analyses of various spectroscopic data, in addition to comparison with the formerly reported data. The antifungal and antibacterial potentials were evaluated toward various microbial strains using disc diffusion assay. Results: A new aminobenzamide derivative, namely fusaribenzamide A (2), and four known metabolites: (22E,24R)-stigmasta-5,7,22-trien-3–ol (1), adenosine (3), p-hydroxyacetophenone (4), and tyrosol (5) were isolated. Fusaribenzamide A (2) possessed significant antifungal activity toward Candida albicans with minimum inhibitory concentration (MIC) value 11.9 mg/disc compared to nystatin (MIC 4.9 mg/disc). Conclusion: The endophytic fungus Fusarium sp. could be considered as a wealthy pool for the isolation of aminobenzamide derivatives. Fusaribenzamide A may be a candidate for the discovery of a promising antifungal agent.

Quality Control of 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Ibrahim, SRM; Mohamed, GA; Khayat, MT; Al Haidari, RA; El-Kholy, AA; Zayed, MF or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles