Tag: M.W=100-150

Recommanded Product: Benzyl Alcohol. Abbasi, YA; Shahida, S; Ali, A; Khan, MH in [Abbasi, Y. A.] Univ Azad Jammu & Kashmir, Dept Chem, Muzaffarabad, AJK, Pakistan; [Abbasi, Y. A.; Ali, A.] Pakistan Inst Nucl Sci & Technol, Chem Div, PO Nilore, Islamabad, Pakistan; [Shahida, S.] Univ Poonch, Rawalakot, Azad Jammu & Ka, Pakistan; [Ali, A.; Khan, M. H.] Women Univ Azad Jammu & Kashmir Bagh, Bagh, Pakistan published Liquid-liquid extraction of mercury(II) from aqueous solution using furosemide in benzyl alcohol in 2019.0, Cited 42.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

A simple, efficient and economical liquid-liquid extraction method has been developed for quantitative extraction of mercury(II) from aqueous buffer solution using furosemide in benzyl alcohol. The effect of various parameters and of various anions and cations on the extraction of mercury(II) was investigated. The separation factor of mercury was quite high in the presence of a number of transition and rare earth metals at pH 3.5. Among strippants, sodium thiosulphate was found most suitable, and the recovery of mercury was noted to be 98%. The stoichiometric composition of the extracted species was found to be [Hg(FS)(2)].

Recommanded Product: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Abbasi, YA; Shahida, S; Ali, A; Khan, MH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O. Recently I am researching about CHLOROPHYLL-A DERIVATIVES; EXTRA RING; CHLORIN; ANTIOXIDANT; FRAGMENTS; GLYCOL, Saw an article supported by the . Published in MAIK NAUKA/INTERPERIODICA/SPRINGER in NEW YORK ,Authors: Tulaeva, LA; Gileva, NV; Belykh, DV. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

The reaction of methyl pheophorbide a with various alcohols in toluene in the presence of dimethylaminopyridine as a base was investigated. Under these conditions, a chemoselective transesterification of the exocyclic ring proceeds without the use of an activating agent (N-methyl-2-chloropyridinium iodide) or a catalyst (molecular iodine).

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Tulaeva, LA; Gileva, NV; Belykh, DV or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: m-Methoxyphenol. Recently I am researching about ASYMMETRIC CATALYSIS; SALEN, Saw an article supported by the . Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Lamb, KJ; Dowsett, MR; North, M; Parker, RR; Whitwood, AC. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

The synthesis of novel tetrahydroquinoxalines by a metal induced one-electron reductive cyclisation of salophen ligands was found to occur when a salophen ligand was treated with chromium(ii) chloride or decamethylcobaltocene.

About m-Methoxyphenol, If you have any questions, you can contact Lamb, KJ; Dowsett, MR; North, M; Parker, RR; Whitwood, AC or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about FEEDBACK ACTIVATION; DRUG-RESISTANCE; DERIVATIVES; BREAST, Saw an article supported by the Major science and technology projects of Guangxi Zhuang Autonomous Region [AA17204090]; Wenzhou science and technology project [Y20170280]; Medical Scientific Research Fund of Zhejiang Province [2019322308]; National Natural Science Funding of ChinaNational Natural Science Foundation of China (NSFC) [21762006]; Specific research project of Guangxi for research bases and talents [2017AD19029]. Published in WILEY in HOBOKEN ,Authors: Xu, LY; Qiu, SS; Yang, LH; Xu, HT; Liu, X; Fan, SQ; Cui, R; Fu, WT; Zhao, CG; Shen, LQ; Wang, LX; Huang, XY. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone. Recommanded Product: 99-93-4

Lung cancer is a leading cause of cancer-related death worldwide. Cyanopyridines and aminocyanopyridines with carbon-nitrogen bonds have been proved to exert significant anticancer, antibacterial, and anti-inflammatory effects. In this study, we showed that aminocyanopyridine 3o and 3k displaying potent antitumor activity via inhibiting the signal transducer and activator of transcription 3 (STAT3) pathway. They blocked the constitutive STAT3 phosphorylation in a dose- and time-dependent manner and regulated the transcription of STAT3 target genes encoding apoptosis factors. Most importantly, 3o also inhibited interleukin-6-induced STAT3 activation and nuclear localization. Furthermore, 3o significantly inhibited the tumor growth of H460-derived xenografts. Taken together, these findings suggest that 3o and 3k are promising therapeutic drug candidates for lung cancer by inhibiting persistent STAT3 signaling.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Xu, LY; Qiu, SS; Yang, LH; Xu, HT; Liu, X; Fan, SQ; Cui, R; Fu, WT; Zhao, CG; Shen, LQ; Wang, LX; Huang, XY or concate me.. Recommanded Product: 99-93-4

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about ELECTROPHILIC DISPLACEMENT-REACTIONS; CATALYZED AEROBIC DEHYDROGENATION; HX-REDUCTIVE-ELIMINATION; CONJUGATE ADDITION; ANTIOXIDANT ACTIVITY; EFFICIENT SYNTHESIS; MOLECULAR-OXYGEN; HECK REACTION; FLAVONOIDS; KETONES, Saw an article supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) – Ministry of Science, ICT & Future Planning [NRF-2016R1A2B4015169]. Product Details of 150-19-6. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Yoo, HS; Son, SH; Cho, YY; Lee, SJ; Jang, HJ; Kim, YM; Kim, DH; Kim, NY; Park, BY; Lee, YS; Kim, NJ. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

A total of 47 flavanones were expediently synthesized via one-pot beta-arylation of chromanones, a class of simple ketones possessing chemically unactivated beta sites, with arylboronic acids via tandem palladium(II) catalysis. This reaction provides a novel route to various flavanones, including natural products such as naringenin trimethyl ether, in yields up to 92%.

Product Details of 150-19-6. About m-Methoxyphenol, If you have any questions, you can contact Yoo, HS; Son, SH; Cho, YY; Lee, SJ; Jang, HJ; Kim, YM; Kim, DH; Kim, NY; Park, BY; Lee, YS; Kim, NJ or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 4-Methoxybenzaldehyde. Authors Zeid, SB; Hamade, A; Najjar, F; Carreaux, F; Eid, S in SPRINGER INTERNATIONAL PUBLISHING AG published article about in [Zeid, Samar Bou; Hamade, Aline; Najjar, Fadia; Eid, Samar] Lebanese Univ, Fac Sci 2, Dept Biol Chem & Biochem, Lab Innovat Therapeut, Fanar, Lebanon; [Zeid, Samar Bou; Carreaux, Francois] Univ Rennes 1, CNRS, ISCR, UMR 6226, 263 Ave Gen Leclerc,Campus Beaulieu, F-35000 Rennes, France in 2021, Cited 43. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Herein we describe the synthesis of five new 2-aryl and 2-alkylimidazolone derivatives via an effective one-pot synthetic strategy assisted by microwave irradiations which allowed us to access the desired product in a reduced time reaction compared to the thermal heating and a slightly better yield (48% compared to 45%). The new imidazolone derivatives were evaluated for their anticancer activity in vitro against MCF-7, MDA-MB-231 and HepG2 cell lines. The results showed good cytotoxic effects for some of these derivatives on both MCF-7 and HepG2 cell lines in the range of 5.7-11.3 mu M. Among the synthesized derivatives, 2ab and 2b showed the strongest activity with IC50 values of 7 and 5.7 mu M (MCF-7) and 6.2 and 8.6 mu M (HepG2), respectively. The cytotoxic activities of these derivatives were moderate compared to those of doxorubicin. However, this product showed higher toxicity in vivo on the development of zebrafish embryos than the synthesized imidazolones. These derivatives at high concentrations exhibited some morphological abnormalities on the embryos.

About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zeid, SB; Hamade, A; Najjar, F; Carreaux, F; Eid, S or concate me.. Quality Control of 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2019.0 MOLECULES published article about TRANSITION-METAL-COMPLEXES; MOLECULAR DOCKING; RUTHENIUM(II) COMPLEXES; ANTICANCER ACTIVITY; CYTOTOXIC ACTIVITY; BINDING PROPERTIES; THERMAL-PROPERTIES; CRYSTAL-STRUCTURE; NI(II) COMPLEX; BSA-BINDING in [Li, Jiahe; Liu, Rongping; Jiang, Jinzhang; Liang, Xing; Huang, Ling; Ma, Zhen] Guangxi Univ, Sch Chem & Chem Engn, Nanning 530004, Guangxi, Peoples R China; [Li, Jiahe; Ma, Zhen] Univ Lisbon, Inst Super Tecn, Ctr Quim Estrutural, Av Rovisco Pais, P-1049001 Lisbon, Portugal; [Huang, Gang; Pan, Lixia] Guangxi Acad Sci, State Key Lab Nonfood Biomass & Enzyme Technol, Natl Engn Res Ctr Nonfood Biorefinery, Nanning 530004, Guangxi, Peoples R China; [Chen, Hailan] Guangxi Univ, Sch Anim Sci & Technol, Nanning 530004, Guangxi, Peoples R China in 2019.0, Cited 85.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4. HPLC of Formula: C7H6O2

A series of ZnCl2 complexes (compounds 1-10) with 4′-(substituted-phenyl)-2,2′:6′,2 ”-terpyridine that bears hydrogen (L-1), p-methyl (L-2), p-methoxy (L-3), p-phenyl (L-4), p-tolyl (L-5), p-hydroxyl (L-6), m-hydroxyl (L-7), o-hydroxyl (L-8), p-carboxyl (L-9), or p-methylsulfonyl (L-10) were prepared and then characterized by H-1 NMR, electrospray mass-spectra (ESI-MS), IR, elemental analysis, and single crystal X-ray diffraction. In vitro cytotoxicity assay was used to monitor the antiproliferative activities against tumor cells. Absorption spectroscopy, fluorescence titration, circular dichroism spectroscopy, and molecular modeling studied the DNA interactions. All of the compounds display interesting photoluminescent properties and different maximal emission peaks due to the difference of the substituent groups. The cell viability studies indicate that the compounds have excellent antiproliferative activity against four human carcinoma cell lines, A549, Bel-7402, MCF-7, and Eca-109, with the lowest IC50 values of 0.33 (10), 0.66 (6), 0.37 (7), and 1.05 (7) mu M, respectively. The spectrophotometric results reveal that the compounds have strong affinity binding with DNA as intercalator and induce DNA conformational transition. Molecular docking studies indicate that the binding is contributed by the pi…pi stacking and hydrogen bonds, providing an order of nucleotide sequence binding selectivity as ATGC > ATAT > GCGC. These compounds intercalate into the base pairs of the DNA of the tumor cells to affect their replication and transcription, and the process is supposed to play an important role in the anticancer mechanism.

HPLC of Formula: C7H6O2. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Li, JH; Liu, RP; Jiang, JZ; Liang, X; Huang, L; Huang, G; Chen, HL; Pan, LX; Ma, Z or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Logsdon, DL; Li, YJ; Sobreira, TJP; Ferreira, CR; Thompson, DH; Cooks, RG in [Logsdon, David L.; Li, Yangjie; Thompson, David H.; Cooks, R. Graham] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA; [Sobreira, Tiago Jose Paschoal; Ferreira, Christina R.; Thompson, David H.; Cooks, R. Graham] Purdue Univ, Bindley Biosci Ctr, W Lafayette, IN 47907 USA published High-Throughput Screening of Reductive Amination Reactions Using Desorption Electrospray Ionization Mass Spectrometry in 2020.0, Cited 18.0. Formula: C7H6O2. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

This study describes the latest generation of a high-throughput screening system that is capable of screening thousands of organic reactions in a single day. This system combines a liquid handling robot with desorption electrospray ionization (DESI) mass spectrometry (MS) for a rapid reaction mixture preparation, accelerated synthesis, and automated MS analysis. A total of 3840 unique reductive amination reactions were screened to demonstrate the throughputs that are capable with the system. Products, byproducts, and intermediates were all monitored in full-scan mass spectra, generating a complete view of the reaction progress. Tandem mass spectrometry experiments were conducted to verify the identity of the products formed. The amine and electrophile reactivity trends represented in the data match what is expected from theory, indicating that the system accurately models the reaction performance. The DESI results correlated well with those generated using more traditional mass spectrometry techniques like liquid chromatography-mass spectrometry, validating the data generated by the system.

About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Logsdon, DL; Li, YJ; Sobreira, TJP; Ferreira, CR; Thompson, DH; Cooks, RG or concate me.. Formula: C7H6O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Synthesis of Chalcone Derivatives by Phthalhydrazide-Functionalized TiO2-Coated Nano-Fe3O4 as a New Heterogeneous Catalyst published in 2021. Formula: C8H8O2, Reprint Addresses Farahi, M (corresponding author), Univ Yasuj, Dept Chem, POB 353, Yasuj 7591874831, Iran.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

Phthalhydrazide immobilized on TiO2-coated nano Fe3O4 (Fe3O4-P) was synthesized and characterized by FT-IR, XRD, SEM, EDS and VSM analysis. The resulting magnetic nanocatalyst was used as a catalyst for the synthesis of chalcone derivatives which affords the desired products in good to excellent yields. This catalyst can be isolated readily after completion of the reaction by an external magnetite field and reused several times without significant loss of activity.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Nia, FM; Farahi, M; Karami, B; Keshavarz, R or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 100-83-4. In 2020.0 SYNTHETIC COMMUN published article about LIGHT-EMITTING-DIODES; CELL-CYCLE ARREST; QUINAZOLINE DERIVATIVES; STEREOSELECTIVE-SYNTHESIS; BIOLOGICAL EVALUATION; ONE-POT; DESIGN; DOCKING; HETEROCYCLES; INHIBITORS in [Fares, Ibrahim M. Z.; Mekky, Ahmed E. M.; Elwahy, Ahmed H. M.; Abdelhamid, Ismail A.] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt in 2020.0, Cited 61.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

A novel series of bis(tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8-ones) and bis(tetrahydrobenzo[4,5]imidazo[2,1-b]quinazolinones) containing amide linkages were regionselectively prepared via a three-component reaction of bis(aldehydes) with dimedone and 3-amino-1,2,4-triazole (or 2-aminobenzimidazole) under conventional heating as well as under microwave irradiation.

Recommanded Product: 100-83-4. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Fares, IMZ; Mekky, AEM; Elwahy, AHM; Abdelhamid, IA or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles