Tag: M.W=100-150

Product Details of 99-93-4. Recently I am researching about DISCOVERY; DESIGN; POTENT; STAPHYLOCOCCI; OPTIMIZATION; IV, Saw an article supported by the National Research Centre (NRC) – Cairo – EgyptNational Research Centre (NRC) [AR110218]. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Ghannam, IAY; Abd El-Meguid, EA; Ali, IH; Sheir, DH; El Kerdawy, AM. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone

A series of new 2-arylbenzothiazole derivatives (4, 5, 6a-j, 7a-i and 8a,b) was synthesized and tested for their antimicrobial activity against different Gram-positive, Gram-negative bacteria and yeast using ciprofloxacin and fluconazole as positive controls for the antibacterial and antifungal activities, respectively. The target compounds showed stronger inhibitory activity against Gram-negative than Gram-positive bacteria. The minimum inhibitory concentration (MIC) values were determined for those compounds showed zone of inhibition >= 13 mm. Based on the MIC values for the tested compounds against E. coli, compounds (4, 5, 6c, 6d, 6g, 6i, 6j, 7b, 7c, 7g and 8a) were selected and tested for their E. coli gyrase inhibitory activity. The tested compounds showed moderate inhibitory activity against E. coli gyrase. Compounds 5, 6c, 6i, 6j and 7b displayed high inhibitory activity against E. coli gyrase with IC50 values below 10 mu M, however, they were less active than ciprofloxacin (E. coli gyrase IC50 = 1.14 mu M). The p-hydroxy-m-methoxy benzothiazole analogue 6c was the most active tested compound (E. coli gyrase IC50 = 4.85 mu M). Quantitative structure-activity relationship (QSAR) study was also implemented for the newly synthesized compounds. The QSAR study indicated that the structural feature that governs the anti-microbial activity for the newly synthesized benzothiazole derivatives is their structural hydrophilic-lipophilic balance what agrees with the chemical intuition where this balance governs their cellular absorption and so their antimicrobial activity. Molecular docking showed that the newly synthesized compounds possess the required structural feature for E. coli gyrase B inhibition through interaction with the key amino acids Asp73 and Gly77.

Product Details of 99-93-4. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Ghannam, IAY; Abd El-Meguid, EA; Ali, IH; Sheir, DH; El Kerdawy, AM or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recently I am researching about CYCLOADDITION; ARYLATION; CONSTRUCTION; REACTIVITY; EPOXYETHER; MECHANISM; ENAMIDES; ARYL, Saw an article supported by the Swiss National Science Foundation (SNSF)Swiss National Science Foundation (SNSF) [200020182798]; EPFL. Recommanded Product: m-Methoxyphenol. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Declas, N; Waser, J. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

We report an Umpolung strategy of enol ethers to generate oxy-allyl cation equivalents based on the use of hypervalent iodine reagents. Under mild basic conditions, the addition of nucleophiles to aryloxy-substituted vinylbenziodoxolone (VBX) reagents, easily available in two steps from silyl alkynes, resulted in the stereoselective formation of substituted aryl enol ethers. The reaction was most efficient with phenols as nucleophiles, but preliminary results were also achieved for C- and N- nucleophiles. In absence of external nucleophiles, the 2-iodobenzoate group of the reagent was transferred. The obtained aryl enol ethers could then be transformed into alpha-difunctionalized ketones by oxidation. The described allyl cation-like reactivity contrast with the well-established vinyl-cation behavior of alkenyl iodonium salts.

About m-Methoxyphenol, If you have any questions, you can contact Declas, N; Waser, J or concate me.. Recommanded Product: m-Methoxyphenol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

El-Hawary, SS; Mohammed, R; El-Din, ME; Hassan, HM; Ali, ZY; Rateb, ME; El Naggar, EB; Othman, EM; Abdelmohsen, UR in [El-Hawary, Seham S.] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Cairo, Egypt; [Mohammed, Rabab; Hassan, Hossam M.] Beni Suef Univ, Fac Pharm, Dept Pharmacognosy, Bani Suwayf, Egypt; [El-Din, Marwa Emad; Hassan, Hossam M.] Nahda Univ, Fac Pharm, Dept Pharmacognosy, Bani Suwayf, Egypt; [Ali, Zeinab Y.] Egyptian Drug Author EDA, Dept Biochem, Giza 12553, Egypt; [Ali, Zeinab Y.] Natl Org Drug Control & Res NODCAR, Giza 12553, Egypt; [Rateb, Mostafa E.] Univ West Scotland, Sch Comp Engn & Phys Sci, Paisley PA1 2BE, Renfrew, Scotland; [El Naggar, El Moataz Bellah] Damanhur Univ, Fac Pharm, Dept Pharmacognosy, Elbehira 22511, Egypt; [Othman, Eman M.] Minia Univ, Fac Pharm, Dept Biochem, Al Minya 61519, Egypt; [Othman, Eman M.] Univ Wurzburg, Bioctr, Dept Bioinformat, Wurzburg, Germany; [Abdelmohsen, Usama Ramadan] Deraya Univ, Fac Pharm, Dept Pharmacognosy, New Minia 61111, Minia, Egypt; [Abdelmohsen, Usama Ramadan] Minia Univ, Fac Pharm, Dept Pharmacognosy, Al Minya 61519, Egypt published Comparative phytochemical analysis of five Egyptian strawberry cultivars (Fragaria x ananassa Duch.) and antidiabetic potential of Festival and Red Merlin cultivars in 2021.0, Cited 70.0. Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

This work aims to explore the differences in phytochemical composition and biological properties of five strawberry hybrids (Fragaria x ananassa Duch.), and highlights the non-edible part (byproduct) as a source of self-remedy natural herb along with fruits. HPLC/DAD/HRESIMS technique was used in the dereplication of ten ethanolic extracts of five strawberry cultivars leaves and fruits (Festival, Red Merlin, Suzana, Tamar and Winter Dawn). Total phenolic and total flavonoid contents were established using Folin-Ciocalteu and aluminum chloride colorimetric assays, respectively. Ethanolic extracts of leaves and fruits from Festival and Red Merlin cultivars were selected to investigate their anti-hyperglycemic activity using streptozotocin-induced diabetic rats. Oxidative stress markers, lipid profile and kidney and liver function tests were assessed. The results revealed different chemical profiles of ten samples with the identification of 37 metabolites, represented mainly as flavonoids and phenolic acid derivatives. Phytochemical investigation resulted in the isolation of seven known phenolic compounds; quercetin, kaempferol, p-coumaric acid, p-tyrosol, methyl gallate, trans-tiliroside and eutigoside A. Suzana cultivar was the richest cultivar with flavonoids and total phenolics except for the total flavonoid content in leaves referred to Festival cultivar. Ethanolic extract of leaves, especially Festival cultivar was the most bioactive one. The results established the role of strawberry leaves along with fruits as an antioxidant and hypoglycemic natural remedy.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact El-Hawary, SS; Mohammed, R; El-Din, ME; Hassan, HM; Ali, ZY; Rateb, ME; El Naggar, EB; Othman, EM; Abdelmohsen, UR or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 100-51-6. Xie, S; Lei, YJ; Wang, YJ; Wang, XQ; Ren, RH; Zhang, ZW in [Xie, Sha; Lei, Yujuan; Wang, Yanjun; Wang, Xueqiu; Ren, Ruihua; Zhang, Zhenwen] Northwest A&F Univ, Coll Enol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China; [Zhang, Zhenwen] Shaanxi Engn Res Ctr Vitiviniculture, Yangling 712100, Shaanxi, Peoples R China published Influence of continental climates on the volatile profile of Cabernet Sauvignon grapes from five Chinese viticulture regions in 2019, Cited 30. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Most Chinese viticulture regions feature a continental monsoon climate with hot-wet summers and dry-cold winters, giving grapes markedly different growing environments compared to the Mediterranean or oceanic climates. This study investigated the influence of continental climates on the volatile compounds of Vitis vinifera L. cv. Cabernet Sauvignon from five Chinese viticulture regions and the relationship between meteorological metrics and volatile concentrations in the 2014 and 2015 vintages. Grape berries from the climatically similar Wujiaqu (WJQ) and Yuquanying (YQY) regions had similar 6/9-carbon (C6/C9) compound and norisoprenoid contents. Berries from the Yantai (YT) and Jingyang (JY) regions with higher temperature and humidity had higher norisoprenoid contents than those from WJQ and YQY regions. Hierarchical clustering analysis showed that the vintage effect on grape volatile profiles prevailed over the regional effect. Grape berries from climatically similar WJQ and YQY regions exhibited similar volatile profiles and from the Deqin(DQ) region with a specific terroir showed significantly different volatile profiles from those of other regions. Pearson correlation analysis showed that (E)-beta-damascenone, beta-ionone, hexanal, 2-hexanol, (Z)-3-hexenol and (E)-2-hexenol were closely associated with minimum and maximum temperature, average relative humidity, sunshine duration and frost-free days, suggesting that these compounds might comprise a signature for distinguishing the volatile profiles of grape berries from different regions. This study would enhance our understanding of grape responses to continental monsoon climate through the accumulation of volatiles.

SDS of cas: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Xie, S; Lei, YJ; Wang, YJ; Wang, XQ; Ren, RH; Zhang, ZW or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. Authors Ma, LN; Zhou, H; Kong, XG; Li, ZH; Duan, HH in AMER CHEMICAL SOC published article about in [Ma, Lina; Kong, Xianggui; Li, Zhenhua] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China; [Zhou, Hua; Duan, Haohong] Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China in 2021, Cited 79. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Lignin presents as a renewable aromatic resource for value-added chemical production. However, it remains challenging to cleavage C-C bonds in lignin under ambient conditions. Electrochemical oxidation as a renewable energy technology presents an attractive alternative to traditional processes. Herein, we report an efficient electrocatalytic strategy for C-alpha-C-beta bond cleavage of the beta-O-4 linkage in lignin model compounds at room temperature with platinum as the anode and tert-butyl hydroperoxides (t-BuOOH in water, 70% aq soln) as the oxidants, exhibiting high yields for the aromatic aldehydes and phenols. This electrocatalytic strategy is demonstrated to be highly selective for the transformation of a broad selection of lignin model dimers, polymeric compound, and even real lignin into the desired aromatic aldehydes. Mechanistic studies indicate that the reaction may proceed via a C-beta radical process involving a peroxide intermediate. This work opens up opportunities in electrocatalysis to selectively break C-alpha-C-beta bonds and transform lignin to valuable chemicals under ambient conditions by using renewable electricity.

HPLC of Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Ma, LN; Zhou, H; Kong, XG; Li, ZH; Duan, HH or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of Benzyl Alcohol. Recently I am researching about LIMITING ACTIVITY-COEFFICIENTS; DILUTION ACTIVITY-COEFFICIENTS; MOLECULAR SIMULATION; BOILING-POINT; MODEL; SOLUBILITY; VOLATILE, Saw an article supported by the American Chemical Society Petroleum Research FundAmerican Chemical Society [56896-UNI6]; Office of Career Strategy at Yale University; Office of Research for Undergraduates at Miami University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Roese, SN; Margulis, GV; Schmidt, AJ; Uzat, CB; Heintz, JD; Paluch, AS. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

Simple expressions are presented to determine if a binary system will exhibit a minimum or maximum boiling azeotrope using conventional free energy calculations using molecular simulation or electronic structure calculations in a continuum solvent. The expressions compare the solvation free energy of each component at infinite dilution relative to itself, requiring four total solvation free energy calculations per binary system. The solvation free energies can be related to intermolecular interactions and, therefore, shed insight into why an azeotrope occurs. The application of the expressions is demonstrated for 2366 binary systems using solvation free energies computed using electronic structure calculations in the SM12, SM8, and SMD universal solvent models. The overall success rate for predicting the correct phase behavior was 0.718, 0.711, and 0.685 for SM12, SM8, and SMD, respectively.

Application In Synthesis of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Roese, SN; Margulis, GV; Schmidt, AJ; Uzat, CB; Heintz, JD; Paluch, AS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C8H8O2. Authors Zhang, XY; Luo, CJ; Chen, XY; Ma, WL; Li, B; Lin, ZR; Chen, XW; Li, YB; Xie, F in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Zhang, Xiangyu; Luo, Chujun; Chen, Xiaoyong; Ma, Weilin; Li, Bin; Lin, Zirui; Chen, Xiuwen; Li, Yibiao; Xie, Feng] Wuyi Univ, Sch Chem & Environm Engn, Jiangmen 529020, Guangdong, Peoples R China in 2021.0, Cited 47.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

A novel catalytic system is reported for the construction of quinazolinones via the carbon-supported acid-catalyzed cascade coupling of isatoic anhydrides with amides and aldehydes. Subsequent selective hydrosilylation of the quinazolinones using a hydrogen-transfer strategy was also explored to provide dihydroquinazolines with structural diversity. The developed methodology proceeds with a broad substrate scope, excellent functional group tolerance, and utilizes a reusable catalyst and air as a green oxidant. (C) 2021 Elsevier Ltd. All rights reserved.

Computed Properties of C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Zhang, XY; Luo, CJ; Chen, XY; Ma, WL; Li, B; Lin, ZR; Chen, XW; Li, YB; Xie, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Mesomorphic, optical, dielectric, and electro-optic properties of azo-ester materials: Effect of lateral methyl and terminal substituents WOS:000664654300059 published article about THERMOTROPIC LIQUID-CRYSTALS; MESOPHASE BEHAVIOR; SIDE-CHAIN; BENZOTHIAZOLE MESOGEN; AZOBENZENE; IMPACT; ORIENTATION; BENZOATES; MONOMERS; SERIES in [Kamal, Salwa J.; Mahmud, H. N. M. Ekramul; Abdullah, Iskandar] Univ Malaya, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Salleh, Noordini M.; Velayutham, Thamil Selvi; Zahid, N. Idayu] Univ Malaya, Ctr Fundamental & Frontier Sci Nanostruct Self As, Fac Sci, Dept Chem, Kuala Lumpur 50603, Malaysia; [Gopal, Sanjeev R.; Velayutham, Thamil Selvi] Univ Malaya, Fac Sci, Low Dimens Mat Res Ctr, Dept Phys, Kuala Lumpur 50603, Malaysia; [Kamal, Salwa J.] Imam Abdulrahman Bin Faisal Univ, Coll Sci, Dept Chem, POB 1982, Dammam 31441, Saudi Arabia in 2021.0, Cited 46.0. Computed Properties of C7H8O2. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

The effect of introducing a lateral methyl substituent and the two different alkoxy terminal groups on the mesophase behavior of three-benzene-ring molecular core of azo-ester compounds bearing 2-methylbutoxy unit on the opposite terminal side (C1-C6) were explored. Their structures were confirmed by several spectroscopic techniques (Fourier transform infrared spectroscopy, H-1 and C-13 nuclear magnetic resonance spectroscopy). The mesomorphic properties of these compounds were studied by differential scanning calorimetry, polarized optical microscopy, and small- and wide-angle X-ray scattering. Except for the un-substituted terminals (C1 and C4), all other derivatives are liquid crystalline, exhibiting enantiotropic nematic liquid crystal phase. The alteration of the alkoxy chain length from methoxy to butoxy at the phenyl ester terminal group (ring A) for each set of laterally-neat and laterally methyl-substituted mesogens decreases the nematic temperature range. A decrease in the mesophase temperature range is also observed when a lateral methyl substituent is incorporated into phenylazo ring of the mesogenic core (ring C). Optical study demonstrated that their absorption spectra are identical in shape due to the structural similarities of the mesogenic core. The corresponding fluorescence spectra exhibited blue-emission with the laterally methyl substituted compounds having a relatively higher fluorescence intensity compared to that of its laterally un-substituted analogues. Furthermore, the laterally methyl-substituted derivatives were subjected to the planar alignment and their dielectric and electro-optic properties were investigated. The nematic phase of the aligned samples shows antiferroelectric switching behavior with spontaneous polarization, P-s similar to 5 mu C/cm(2). (C) 2021 Elsevier B.V. All rights reserved.

Computed Properties of C7H8O2. About Mequinol, If you have any questions, you can contact Kamal, SJ; Salleh, NM; Mahmud, HNME; Abdullah, I; Gopal, SR; Velayutham, TS; Zahid, NI or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Synthesis, Antimicrobial Evaluation and Molecular Docking of Some Potential 2,6-disubstituted 1H-Benzimidazoles; Non-Classical Antifolates WOS:000489963500010 published article about DIHYDROFOLATE-REDUCTASE INHIBITORS; ONE-POT PREPARATION; 2-SUBSTITUTED BENZIMIDAZOLES; BIOLOGICAL EVALUATION; SELECTIVE INHIBITORS; DHFR INHIBITORS; DESIGN; DERIVATIVES; RESISTANT in [Harer, Sunil] Savitribai Phule Pune Univ, Sharadchandra Pawar Coll Pharm, Fac Pharmaceut Sci, Dept Pharmaceut Chem, Pune 412409, Maharashtra, India; [Bhatia, Manish; Kawade, Vikram] Shivaji Univ, Bharati Vidyapeeth Coll Pharm, Fac Pharmaceut Sci, Dept Pharmaceut Chem, Kolhapur, Maharashtra, India in 2019.0, Cited 49.0. Recommanded Product: 4′-Hydroxyacetophenone. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4

Background: Dihydrofolate reductase is one of the important enzymes for thymidylate and purine synthesis in micro-organisms. A large number of drugs have been designed to inhibit microbial DHFR but over the period of time some drugs have developed resistance and cross reactivity towards the enzyme. Over the past few decades, benzimidazoles, triazoles and their derivatives have been grabbing the attention of the synthetic chemists for their wide gamut of antibacterial and antifungal activities targeting microbial protein DHFR. Objective: Our goal behind present investigation is to explore benzimidazoles class of drugs as microbial DHFR inhibitors by studying ligand-receptor binding interactions, in vitro enzyme inhibition assay and confirmation of anti-microbial activity against selected pathogenic micro-organisms. Method: A library containing thirty novel 2,6-disubstituted 1H-benzimidazoles was synthesized by one pot condensation of o-nitro aniline or 2,4-dinitro aniline with series of aldehydes or acetophenones using Na2S2O4 or SnCl2 respectively and reflux for 5-6hr. Structures of compounds have been confirmed by spectroscopic methods as 1H and C-13 NMR, FT-IR and MS. In vitro DHFR inhibition study was performed by using Epoch microplate reader and IC50 of the test compounds was compared with Trimethoprim. In vitro antimicrobial activity was performed against selected clinical pathogens by agar disk diffusion method and MIC (mu g/mL) was reported. Results: Moderate to good level of DHFR inhibition was observed with IC50 values in the range of 7-23 mu M. Compounds B1, B19, B22, B24 and B30 has expressed 1.1 to 1.4 folds more prominent DHFR inhibitory activity as compared to standard Trimethoprim. Remarkable antimicrobial activity was exhibited by B1, B19, B22, B24 and B30. Molecular docking study has revealed perfect binding of test ligands with key amino acids of DHFR as Phe31, Ile94, Ile5, Asp27, Gln32 and Phe36. Conclusion: Nature of 1H-benzimidazole substituents at position 2 and 6 had influence over magnitude and type of molecular binding and variation in the biological activity. Present series of 1H-benzimidazoles could be considered promising broad-spectrum antimicrobial candidates that deserve in future for preclinical antimicrobial evaluation and development of newer antimicrobial agents targeting microbial DHFR.

Recommanded Product: 4′-Hydroxyacetophenone. About 4′-Hydroxyacetophenone, If you have any questions, you can contact Harer, S; Bhatia, M; Kawade, V or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Asghariganjeh, MR; Mohammadi, AA; Tahanpesar, E; Rayatzadeh, A; Makarem, S in [Asghariganjeh, Mohammad Reza] Islamic Azad Univ, Khuzestan Sci & Res Branch, Dept Chem, Ahwaz, Iran; [Asghariganjeh, Mohammad Reza; Tahanpesar, Elham; Rayatzadeh, Ayeh] Islamic Azad Univ, Ahvaz Branch, Dept Chem, Ahwaz, Iran; [Mohammadi, Ali Asghar] Chem & Chem Engn Res Ctr Iran CCERCI, Tehran 14335186, Iran; [Makarem, Somayeh] Islamic Azad Univ, Karaj Branch, Dept Chem, Karaj, Iran published Electro-organic synthesis of tetrahydroimidazo[1,2-a]pyridin-5(1H)-one via a multicomponent reaction in 2021, Cited 49. Name: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Electro-synthesis through a one-pot three-component condensation of corresponding aldehydes, Meldrum’s acid, and 2-(nitromethylene)imidazolidine resulted in a series of novel tetrahydroimidazo[1,2-a]pyridine-5(1H)-one derivatives containing an electronegative pharmacophore (=CNO2). The process was carried out in propanol medium with sodium bromide presented as electrolyte, inside an undivided cell with good to excellent yields. As a powerful entry into fused polycyclic structures related to bioactive heterocycles, this green protocol shows great potential. [GRAPHICS] .

Name: 4-Methoxybenzaldehyde. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Asghariganjeh, MR; Mohammadi, AA; Tahanpesar, E; Rayatzadeh, A; Makarem, S or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles