Tag: M.W=100-150

Quality Control of Benzyl Alcohol. Cho, CW; Zhao, Y; Yun, YS in [Cho, Chul-Woong; Zhao, Yufeng; Yun, Yeoung-Sang] Chonbuk Natl Univ, Sch Chem Engn, 567 Baekje Dearo, Jeonju 561756, Chonbuk, South Korea published QSAR modelling for predicting adsorption of neutral, cationic, and anionic pharmaceuticals and other neutral compounds to microalgae Chlorella vulgaris in aquatic environment in 2019, Cited 43. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Environmental fate or transport of pharmaceutical waste depends on the adsorptive interactions of pharmaceuticals with various environmental phases e.g. soil, sediment, microalgae, and bacteria etc. Therefore, it is important to understand these adsorptive interactions. As part of the study, we studied the adsorptive interaction of 30 chemicals with microalgae, i.e. Chlorella vulgaris, because it is ubiquitous and its surface area occupies a high proportion in aquatic environments. For this study, isotherms between C vulgaris and 30 micropollutants in neutral and ionic forms (i.e. 15 cations, 5 anions, and 10 neutrals) were experimentally measured, and their adsorptive affinities were then theoretically predicted based on the concept of the linear free energy relationship. For modeling, the dataset was divided into a training set and a test set, where the training set was used for model development and the test set was performed for model validation. This process was repeated ten times. Finally, we suggested one model which has high predictability in R-2 of 0.96 and standard error (SE) of 0.17 log unit for the training set, R-2 of 0.818 and SE = 0.217 log unit for the test set, and R-2 of 0.926 and SE of 0.169 log unit for the total dataset. Moreover, it was found that dispersive force, H-bond basicity, molecular volume, and electrostatic interaction of anion significantly contribute to the model developed based on the entire dataset. Here, dispersive and hydrophobic interactions (proportional to the magnitude of molecular size) are main attractive forces, while the rest cases are repulsive. In addition, it was found that the adsorption property of the surface of C. vulgaris differs from those of Gram negative bacteria Escherichia coli and dissolved organic matters in an aquatic environment. (C) 2018 Elsevier Ltd. All rights reserved.

Quality Control of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Cho, CW; Zhao, Y; Yun, YS or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Mrdjan, GS; Matijevic, BM; Vastag, GG; Bozic, AR; Marinkovic, AD; Milcic, MK; Stojiljkovic, IN in [Mrdjan, Gorana S.; Matijevic, Borko M.; Vastag, Gyongyi Gy] Univ Novi Sad, Fac Sci, Dept Chem Biochem & Environm Protect, Trg Dositeja Obradovica 3, Novi Sad 21000, Serbia; [Bozic, Aleksandra R.] Belgrade Polytech, Brankova 17, Belgrade 11000, Serbia; [Marinkovic, Aleksandar D.] Univ Belgrade, Fac Technol & Met, Karnegijeva 4, Belgrade 11000, Serbia; [Milcic, Milos K.] Univ Belgrade, Fac Chem, Studentski Trg 12-16, Belgrade 11000, Serbia; [Stojiljkovic, Ivana N.] Univ Belgrade, Fac Forestry, Kneza Viseslava 1, Belgrade 11000, Serbia published Synthesis, solvent interactions and computational study of monocarbohydrazones in 2020.0, Cited 43.0. HPLC of Formula: C7H6O2. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

Carbohydrazones are compounds that are increasingly studied due to their wide potential biological activity. Monocarbohydrazones (mCHs), as one of the carbohydrazone derivatives, so far have been poorly investigated. For a more detailed study, in this paper, eighteen compounds of monocarbohydrazones (eight known and ten newly synthesized derivatives) were synthesized and characterized using NMR and IR spectroscopy. As carbohydrazones show E/Z isomerization caused by the presence of the imino group, some of the synthesized mCHs are in the form of a mixture of these two isomers. The effects of specific and nonspecific solvent-solute interactions on the UV absorption maxima shifts were evaluated using linear free energy relationships principles, i.e., using Kamlet-Taft’s and Catalan’s models. For more information about interactions between dissolved substance and the surrounding medium, correlations have been made with Hansen’s solubility parameters. The influence of the structure on the spectral behavior of the compounds tested was interpreted using Hammett’s equation. Experimentally obtained physicochemical properties of mCHs were compared to and confirmed with computational methods that included TD-DFT calculations and MP2 geometry optimizations. Graphic abstract

HPLC of Formula: C7H6O2. Bye, fridends, I hope you can learn more about C7H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Fe3O4/ZnO/MWCNTs magnetic nanocomposites promoted synthesis of new chromeno pyrano [2,3-d]thiazins: Investigation of antioxidant and antibacterial activities WOS:000607783400001 published article about MULTICOMPONENT REACTIONS; EFFICIENT SYNTHESIS; DERIVATIVES; KF/CLINOPTILOLITE; NANOSTRUCTURES; ISOCYANIDES; CELL in [Dadashi, Hani; Hajinasiri, Rahimeh; Hossaini, Zinatossadat] Islamic Azad Univ, Dept Chem, Qaemshahr Branch, Qaemshahr, Iran in 2021, Cited 69. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5. SDS of cas: 123-11-5

The Fe3O4/ZnO/MWCNTs magnetic nanocomposites as a high-performance organomettalic catalyst were employed for the preparation of new chromeno pyrano [2,3-d]thiazins derivatives in high yields via the five component reactions of 2-hydroxyacetophenone or its derivatives, dimethyl carbonate, aldehydes, malononitrile or ethyl 2-cyanoacetate, and isothiocyanates in ionic liquid at room temperature. The Fe3O4/ZnO/MWCNTs MNCs were synthesized using ionic liquid [OMIM]Br as a stabilizer and soft template. As well Fe3O4/ZnO/MWCNTs MNCs show a good improvement in the yield of the product and showed significant reusable ability. Due to having NH group in synthesized compounds, we investigate antioxidant property of some synthesized compounds by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment. Furthermore, the disk diffusion test on Gram-positive and Gram-negative bacteria is utilized for investigation of antimicrobial activity of some chromeno pyrano [2,3-d]thiazins. The achieved outcomes of this experiment demonstrate that these synthesized compounds could prevent from growth of bacteria. Short time of reaction, high yields of product, easy separation of catalyst, and products are some benefits of this process.

Welcome to talk about 123-11-5, If you have any questions, you can contact Dadashi, H; Hajinasiri, R; Hossaini, Z or send Email.. SDS of cas: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Correlation between the structure and skin permeability of compounds WOS:000652602100026 published article about PREDICTION; MOLECULES in [Zeng, Ruolan; Deng, Jiyong; Dang, Limin; Yu, Xinliang] Hunan Inst Engn, Hunan Prov Key Lab Environm Catalysis & Waste Reg, Coll Mat & Chem Engn, Xiangtan 411104, Hunan, Peoples R China in 2021, Cited 23. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5. Safety of Mequinol

A three-descriptor quantitative structure-activity/toxicity relationship (QSAR/QSTR) model was developed for the skin permeability of a sufficiently large data set consisting of 274 compounds, by applying support vector machine (SVM) together with genetic algorithm. The optimal SVM model possesses the coefficient of determination R-2 of 0.946 and root mean square (rms) error of 0.253 for the training set of 139 compounds; and a R-2 of 0.872 and rms of 0.302 for the test set of 135 compounds. Compared with other models reported in the literature, our SVM model shows better statistical performance in a model that deals with more samples in the test set. Therefore, applying a SVM algorithm to develop a nonlinear QSAR model for skin permeability was achieved.

Safety of Mequinol. About Mequinol, If you have any questions, you can contact Zeng, RL; Deng, JY; Dang, LM; Yu, XL or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C8H8O2. Hernandez, C; Moreno, G; Herrera, A; Cardona, W in [Hernandez, Cristian; Moreno, Gustavo; Herrera-R, Angie; Cardona-G, Wilson] Univ Antioquia UdeA, Inst Chem, Fac Exact & Nat Sci, Quim Plantas Colombianas, Calle 70 52-21, Medellin 1226, Colombia published New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer Cells in 2021, Cited 46. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

We synthesized twelve hybrids based on curcumin and resveratrol, and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated against SW480 human colon adenocarcinoma cells, its metastatic derivative SW620, along with the non-malignant CHO-K1 cell line. Among the tested compounds, hybrids 3e and 3i (for SW480) and 3a, 3e and 3k (for SW620) displayed the best cytotoxic activity with IC50 values ranging from 11.52 +/- 2.78 to 29.33 +/- 4.73 mu M for both cell lines, with selectivity indices (SI) higher than 1, after 48 h of treatment. Selectivity indices were even higher than those reported for the reference drug, 5-fluorouracil (SI = 0.96), the starting compound resveratrol (SI = 0.45) and the equimolar mixture of curcumin plus resveratrol (SI = 0.77). The previous hybrids showed good antiproliferative activity.

Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 100-83-4. In 2020.0 CHEMISTRYSELECT published article about BIOLOGICAL EVALUATIONS; CHEMISTRY; EFFICIENT; HETEROCYCLES; FRAMEWORK; SOLVENT; ANALOGS; DESIGN in [Nazeef, Mohd; Tiwari, Saurabh Kumar; Yadav, Vikas; Ansari, Saif; Siddiqui, I. R.] Univ Allahabad, Lab Green Synth, Dept Chem, Allahabad 211002, Uttar Pradesh, India; [Saquib, Mohammad] Univ Allahabad, Dept Chem, Allahabad 211002, Uttar Pradesh, India; [Sagir, Hozeyfa] Paliwal PG Coll, Dept Chem, Shikohabad 283135, India; [Hussain, Mohd. Kamil] Govt Raza PG Coll, Dept Chem, Rampur 244901, India in 2020.0, Cited 46.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

A series of benzo[a]chromeno[2,3-c]phenazine derivatives were synthesized through an efficient one-pot, multicomponent eco-friendly reaction of 2-hydroxynaphthalene-1,4-dione, o-phenylenediamines, cyclic 1,3-dicarbonyl compounds and aromatic aldehydes, promoted by glycerol. To the best of our knowledge this is the first catalyst free protocol for synthesis of this important scaffold having potential applications in medicinal and materials chemistry. Other important attributes of the present method are the use of glycerol as a bio-renewable and biodegradable reaction medium-cum-promoter, use of readily available substrates, mild reaction conditions, operational simplicity, broad substrate scope, short reaction time, easy workup, and high yields and atom efficiency, which makes the disclosed protocol a superior alternative to existing methods.

Product Details of 100-83-4. Bye, fridends, I hope you can learn more about C7H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 4′-Hydroxyacetophenone. Eltoukhy, A; Jia, Y; Nahurira, R; Abo-Kadoum, MA; Khokhar, I; Wang, JH; Yan, YC in [Eltoukhy, Adel; Jia, Yang; Nahurira, Ruth; Khokhar, Ibatsam; Wang, Junhuan; Yan, Yanchun] Chinese Acad Agr Sci, Grad Sch, Beijing 100081, Peoples R China; [Eltoukhy, Adel; Abo-Kadoum, M. A.] Al Azhar Univ, Dept Bot & Microbiol, Fac Sci, Assiut 71524, Egypt; [Abo-Kadoum, M. A.] Southwest Univ, Inst Modern Biopharmaceut, Sch Life Sci, Chongqing 400715, Peoples R China published Biodegradation of endocrine disruptor Bisphenol A by Pseudomonas putida strain YC-AE1 isolated from polluted soil, Guangdong, China in 2020.0, Cited 55.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

Background Bisphenol A is an important organic chemical as an intermediate, final and inert ingredient in manufacturing of many important products like polycarbonate plastics, epoxy resins, flame retardants, food-drink packaging coating, and other. BPA is an endocrine disruptor compound that mimics the function of estrogen causing damage to reproductive organs. Bacterial degradation has been consider as a cost effective and eco-friendly method for BPA degradation compared with physical and chemical methods. This study aimed to isolate and identify bacterial strain capable to degrade and tolerate high concentrations of this pollutant, studying the factors affecting the degradation process and study the degradation mechanism of this strain. Results YC-AE1 is a Gram negative bacterial strain isolated from soil and identified as Pseudomonas putida by 16S rRNA gene sequence and BIOLOG identification system. This strain found to have a high capacity to degrade the endocrine disruptor Bisphenol A (BPA). Response surface methodology using central composite design was used to statistically optimize the environmental factors during BPA degradation and the results obtained by significant model were 7.2, 30 degrees C and 2.5% for optimum initial pH, temperature and inoculum size, respectively. Prolonged incubation period with low NaCl concentration improve the biodegradation of BPA. Analysis of variance (ANOVA) showed high coefficient of determination, R-2 and Adj-R-2 which were 0.9979 and 0.9935, respectively. Substrate analysis found that, strain YC-AE1 could degrade a wide variety of bisphenol A-related pollutants such as bisphenol B, bisphenol F, bisphenol S, Dibutyl phthalate, Diethylhexyl phthalate and Diethyl phthalate in varying proportion. Pseudomonas putida YC-AE1 showed high ability to degrade a wide range of BPA concentrations (0.5-1000 mg l(- 1)) with completely degradation for 500 mg l(- 1) within 72 h. Metabolic intermediates detected in this study by HPLC-MS were identified as 4,4-dihydroxy-alpha-methylstilbene, p-hydroxybenzaldeyde, p-hydroxyacetophenone, 4-hydroxyphenylacetate, 4-hydroxyphenacyl alcohol, 2,2-bis(4-hydroxyphenyl)-1-propanol, 1,2-bis(4-hydroxyphenyl)-2-propanol and 2,2-bis(4-hydroxyphenyl) propanoate. Conclusions This study reports Pseudomonas putida YC-AE1 as BPA biodegrader with high performance in degradation and tolerance to high BPA concentration. It exhibited strong degradation capacity and prominent adaptability towards a wide range of environmental conditions. Moreover, it degrades BPA in a short time via two different degradation pathways.

Welcome to talk about 99-93-4, If you have any questions, you can contact Eltoukhy, A; Jia, Y; Nahurira, R; Abo-Kadoum, MA; Khokhar, I; Wang, JH; Yan, YC or send Email.. Application In Synthesis of 4′-Hydroxyacetophenone

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C8H8O2. Authors Podunavac, M; Mailyan, AK; Jackson, JJ; Lovy, A; Farias, P; Huerta, H; Molgo, J; Cardenas, C; Zakarian, A in WILEY-V C H VERLAG GMBH published article about in [Podunavac, Masa; Mailyan, Artur K.; Jackson, Jeffrey J.; Cardenas, Cesar; Zakarian, Armen] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA; [Lovy, Alenka; Farias, Paula; Huerta, Hernan; Cardenas, Cesar] Univ Mayor, Ctr Integrat Biol, Fac Sci, Gerosci Ctr Brain Hlth & Metab, Santiago, Chile; [Molgo, Jordi] Univ Paris Saclay, CEA, Inst Sci Vivant Frederic Joliot,Serv Ingn Mol San, ERL CNRS N 9004,Dept Medicaments & Technol Sante, Batiment 152,Point Courrier 24, F-91191 Gif Sur Yvette, France; [Cardenas, Cesar] Buck Inst Res Aging, Novato, CA 94945 USA in 2021.0, Cited 33.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

The scalable synthesis of the oxaquinolizidine marine natural product desmethylxestospongin B is based on the early application of Ireland-Claisen rearrangement, macrolactamization, and a late-stage installation of the oxaquinolizidine units by lactam reduction. The synthesis serves as the source of material to investigate calcium signaling and its effect on mitochondrial metabolism in various cell types, including cancer cells.

Formula: C8H8O2. About 4-Methoxybenzaldehyde, If you have any questions, you can contact Podunavac, M; Mailyan, AK; Jackson, JJ; Lovy, A; Farias, P; Huerta, H; Molgo, J; Cardenas, C; Zakarian, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2019 GREEN CHEM published article about AEROBIC OXIDATIVE HYDROXYLATION; HIGHLY EFFICIENT CONVERSION; ARYL BORONIC ACIDS; IPSO-HYDROXYLATION; VISIBLE-LIGHT; CATALYZED HYDROXYLATION; PHOTOREDOX CATALYSIS; PHENOLS; MILD; GENERATION in [Xu, Yu-Ting; Li, Chen-Yuan; Huang, Xiao-Bo; Gao, Wen-Xia; Zhou, Yun-Bing; Liu, Miao-Chang; Wu, Hua-Yue] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China in 2019, Cited 46. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Safety of 4′-Hydroxyacetophenone

Photoinduced hydroxylation of boronic acids with molecular oxygen under photocatalyst-free conditions is reported, providing a green entry to a variety of phenols and aliphatic alcohols in a highly concise fashion. This new protocol features photocatalyst-free conditions, wide substrate scope and excellent functional group compatibility.

Safety of 4′-Hydroxyacetophenone. Welcome to talk about 99-93-4, If you have any questions, you can contact Xu, YT; Li, CY; Huang, XB; Gao, WX; Zhou, YB; Liu, MC; Wu, HY or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of (E)-2-Methylbut-2-enoic acid. Chen, Z; Liu, F; Liu, NN in [Chen, Zhou; Liu, Feng; Liu, Nannan] Auburn Univ, Dept Entomol & Plant Pathol, Auburn, AL 36849 USA published Human Odour Coding in the Yellow Fever Mosquito, Aedes aegypti in 2019, Cited 45. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1.

Insects use their olfactory systems to obtain chemical information on mating partners, oviposition sites and food. The yellow fever mosquito Aedes aegypti, an important vector of human infectious diseases, shows strong preference for human blood meals. This study investigated the chemical basis of host detection by characterizing the neuronal responses of antenna! olfactory sensilla of female Ae. aegypti to 103 compounds from human skin emanations. The effect of blood feeding on the responses of olfactory sensilla to these odorants was examined as well. Sensilla SBTII, GP, and three functional subtypes of SST (SST1, SST2, and SST3) responded to most of the compounds tested. Olfactory receptor neurons (ORNs) ‘A’ and ‘B’ in the trichoid sensilla, either activated or inhibited, were involved in the odour coding process. Compounds from different chemical classes elicited responses with different temporal structures and different response patterns across the olfactory sensilla. Except for their increased responses to several odorants, blood-fed mosquitoes generally evoked reduced responses to specific aldehydes, alcohols, aliphatics/aromatics, ketones, and amines through the SST1, SST2, SBTI, SBTII and GP sensilla. The odorants eliciting diminished responses in female mosquitoes after blood feeding may be important in Ae. aegypti host-seeking activity and thus can be candidates for mosquito attractants in the process of this disease vector management.

Bye, fridends, I hope you can learn more about C5H8O2, If you have any questions, you can browse other blog as well. See you lster.. Safety of (E)-2-Methylbut-2-enoic acid

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles