Tag: M.W=100-150

Recently I am researching about VISCERAL LEISHMANIASIS; IN-VITRO; 2-SUBSTITUTED QUINOLINES; BIOLOGICAL EVALUATION; ANTIMALARIAL; CHEMOTHERAPY; DERIVATIVES; COMPLEXES; DISCOVERY; EFFICACY, Saw an article supported by the . Safety of 4′-Hydroxyacetophenone. Published in HINDAWI LTD in LONDON ,Authors: Abdelwahid, MAS; Elsaman, T; Mohamed, MS; Latif, SA; Mukhtar, MM; Mohamed, MA. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone

Leishmaniasis is a fatal neglected parasitic disease caused by protozoa of the genus Leishmania and transmitted to humans by different species of phlebotomine sandflies. The disease incidence continues to increase due to lack of vaccines and prophylactic drugs. Drugs commonly used for the treatment are frequently toxic and highly expensive. The problem of these drugs is further complicated by the development of resistance. Thus, there is an urgent need to develop new antileishmanial drug candidates. The aim of this study was to synthesize certain quinoline-4-carboxylic acids, confirm their chemical structures, and evaluate their antileishmanial activity. Pfitzinger reaction was employed to synthesize fifteen quinoline-4-carboxylic acids (Q1-Q15) by reacting equimolar mixtures of isatin derivatives and appropriate -methyl ketone. The products were purified, and their respective chemical structures were deduced using various spectral tools (IR, MS, H-1 NMR, and C-13 NMR). Then, they were investigated against L. donovani promastigote (clinical isolate) in different concentration levels (200g/mL to 1.56g/mL) against sodium stibogluconate and amphotericin B as positive controls. The IC50 for each compound was determined and manipulated statistically. Among these compounds, Q1 (2-methylquinoline-4-carboxylic acid) was found to be the most active in terms of IC50.

Safety of 4′-Hydroxyacetophenone. Welcome to talk about 99-93-4, If you have any questions, you can contact Abdelwahid, MAS; Elsaman, T; Mohamed, MS; Latif, SA; Mukhtar, MM; Mohamed, MA or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 123-11-5. I found the field of Chemistry very interesting. Saw the article Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products published in 2021.0, Reprint Addresses Waldmann, H (corresponding author), Max Planck Inst Mol Physiol, Dept Chem Biol, Otto Hahn Str 1, D-44227 Dortmund, Germany.; Waldmann, H (corresponding author), Tech Univ Dortmund, Fac Chem, Chem Biol, Otto Hahn Str 6, D-44221 Dortmund, Germany.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde.

Natural product (NP) structures are a rich source of inspiration for the discovery of new biologically relevant chemical matter. In natural product inspired pseudo-NPs, NP-derived fragments are combined de novo in unprecedented arrangements. Described here is the design and synthesis of a 155-member pyrroquinoline pseudo-NP collection in which fragments characteristic of the tetrahydroquinoline and pyrrolidine NP classes are combined with eight different connectivities and regioisomeric arrangements. Cheminformatic analysis and biological evaluation of the compound collection by means of phenotyping in the morphological cell painting assay followed by principal component analysis revealed that the pseudo-NP classes are chemically diverse and that bioactivity patterns differ markedly, and are dependent on connectivity and regioisomeric arrangement of the fragments.

Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 150-19-6. Recently I am researching about RADICAL-MOLECULE REACTIONS; TRANSITION-STATE MODEL; THERMAL-DECOMPOSITION; LIGNOCELLULOSIC BIOMASS; ANISOLE PYROLYSIS; FLAME STRUCTURE; RATE CONSTANTS; KINETICS; OH; MECHANISM, Saw an article supported by the Fundamental Research Funds for the Central Universities of ChinaFundamental Research Funds for the Central Universities [2020ZDPYMS05]; Shanxi Scholarship Council of China [2020-115]. Published in ELSEVIER in AMSTERDAM ,Authors: Wang, QD; Sun, MM; Liang, JH. The CAS is 150-19-6. Through research, I have a further understanding and discovery of m-Methoxyphenol

The growing interest in the use of bio-oils requires a detailed understanding of its combustion chemical kinetics. Bio-oils contain a large variety of oxygenated organic species, in which substituted phenolic compounds are among the most significant fractions. Hence, accurate assessment of key reaction rate constants and systematically investigated the structural effect on the reactivity are critical. This work reports a systematic theoretical study of the hydrogen abstraction reactions from phenol, anisole, o-guaiacol, m-guaiacol, and p-guaiacol, which are considered as reference components in bio-oil surrogates. The hydrogen abstraction reactions by five different radicals (H/CH3/O(P-3)/OH/HO2) are investigated at ROCBS-QB3//M06-2X/cc-pVTZ level. The highpressure limit rate constants are computed via transition state theory with Eckart tunnelling and the 1-D hindered rotor approximation. Comparisons of site-specific hydrogen abstractions from the studied species with other related species are performed to understand the effects of the aromatic ring and side-chain substituent on hydrogen abstractions.

Welcome to talk about 150-19-6, If you have any questions, you can contact Wang, QD; Sun, MM; Liang, JH or send Email.. Product Details of 150-19-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 4′-Hydroxyacetophenone. Jeong, J; Kim, KH; Kim, DY; Chandrasekaran, G; Kim, M; Pagire, SH; Dighe, M; Choi, EY; Bak, SM; Kim, EY; Shin, MG; Choi, SY; Ahn, JH in [Jeong, Jieun; Kim, Minhee; Pagire, Suvarna H.; Dighe, Mahesh; Ahn, Jin Hee] Gwangju Inst Sci & Technol, Dept Chem, Gwangju 61005, South Korea; [Kim, Kun-Hee; Chandrasekaran, Gopalakrishnan; Choi, Seok-Yong] Chonnam Natl Univ, Dept Biomed Sci, Med Sch, Gwangju, South Korea; [Kim, Dong-Young] Univ Ulsan, Coll Med, Dept Biomed Sci, Seoul, South Korea; [Bak, Su-Min; Kim, Eun-Young] Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, Seoul, South Korea; [Bak, Su-Min; Kim, Eun-Young] Kyung Hee Univ, Dept Biol, Seoul, South Korea; [Shin, Myung-Geun] Chonnam Natl Univ, Dept Lab Med, Med Sch, Gwangju, South Korea published Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model in 2019.0, Cited 18.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.

A new series of 1,3-diketone, heterocyclic and alpha, beta-unsaturated derivatives were synthesized and evaluated for their AhR antagonist activity using zebrafish and mammalian cells. Compounds 1b, 2c, 3b and 5b showed significant AhR antagonist activity in a transgenic zebrafish model. Among them, compound 3b, and 5b were found to have excellent AhR antagonist activity with IC50 of 3.36 nM and 8.3 nM in a luciferase reporter gene assay. In stem cell proliferation assay, compound 5b elicited marked HSC expansion.

About 4′-Hydroxyacetophenone, If you have any questions, you can contact Jeong, J; Kim, KH; Kim, DY; Chandrasekaran, G; Kim, M; Pagire, SH; Dighe, M; Choi, EY; Bak, SM; Kim, EY; Shin, MG; Choi, SY; Ahn, JH or concate me.. Recommanded Product: 4′-Hydroxyacetophenone

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 150-76-5. In 2021.0 SYNTHETIC COMMUN published article about ONE-POT SYNTHESIS; MEDIATED HYDROARYLATION; ASYMMETRIC-SYNTHESIS; DIHYDROCOUMARINS; COUMARINS; DERIVATIVES; EFFICIENT; 4-ARYL-3,4-DIHYDROBENZOPYRAN-2-ONES; 3,4-DIHYDROCOUMARINS; FLAVONOIDS in [Huu-Phuoc Le; Cong-Thang Duong; Xuan-Triet Nguyen; Thi Xuan Thi Luu] Univ Sci, Dept Organ Chem, Ho Chi Minh City, Vietnam; [Thi Xuan Thi Luu] Vietnam Natl Univ, Dept Chem, Ho Chi Minh City, Vietnam in 2021.0, Cited 55.0. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5.

Amberlyst 15 resin supported the tandem reaction of cinnamic acids with phenols under solvent-free reaction condition has been introduced to afford 4-aryl-3,4-dihydrocoumarin (neoflavanone) derivatives. The efficiency of solid acidic sulfonic resin (A-15) has been illustrated in two reaction activation methods such as microwave irradiation and conventional heating. The important roles of Amberlyst 15 have been emphasized strongly through the high yields of 4-aryl-3,4-dihydrocoumarin in the shorter time under the assistance of microwave irradiation than of conventional heating, and its high recovery and reusability for six catalyst runs. The original catalyst as well as the recycled catalyst were characterized by XRD and FE-SEM to study the correlation of the surface of reused catalyst and its recyclability.

SDS of cas: 150-76-5. Bye, fridends, I hope you can learn more about C7H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Manzano, JS; Wang, H; Slowing, II in AMER CHEMICAL SOC published article about PERIODIC MINIMAL-SURFACES; FREE AEROBIC OXIDATION; ALCOHOL OXIDATION; BENZYL ALCOHOL; HETEROGENEOUS COPPER; SELECTIVE OXIDATION; HYDROGEN-PEROXIDE; STEREOLITHOGRAPHY; POLYMERIZATION; BENZALDEHYDE in [Manzano, J. Sebastian; Wang, Hsin; Slowing, Igor I.] US DOE, Ames Lab, Ames, IA 50011 USA; [Manzano, J. Sebastian; Wang, Hsin; Slowing, Igor I.] Iowa State Univ, Dept Chem, Ames, IA 50011 USA in 2019.0, Cited 70.0. SDS of cas: 100-51-6. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Identification of 3D printable materials is crucial to expand the breadth of physical and chemical properties attainable by additive manufacturing. Stereolithography (SLA), a wide-spread 3D printing method based on resin photopolymerization, is ideally suited for exploring a large variety of monomers to produce functional three-dimensional solids of diverse properties. However, for most commercial SLA printers, screening monomers and resin compositions requires large volumes (similar to 150 mL) in each printing cycle, making the process costly and inefficient. Herein, a high throughput block (HTB) adaptor was developed to screen arrays of monomers and resin compositions, consuming lower volumes (<2 mL) and less time per print (<1/16 based on a 4 x 4 matrix) than using the original hardware. By use of this approach, a library of materials with different surface hydrophobicities were 3D printed by including long chain acrylates in the resins. In addition, several metal salts were dissolved in an acrylic acid-based resin, 3D printed, and screened as benzyl alcohol oxidation catalysts. Cu(II)-based resins produced the most active structures. Combinations of Cu(II) and long chain acrylate monomers were then used to 3D print complex catalytic architectures with varying degrees of hydrophobicity. Linear relationships were observed between 3D printed surface area, surface hydrophobicity, and catalyst performance. For a high surface Schwarz P topology ca. 60% enhancement in the catalytic activity of Cu(II) was attained by replacing the parent resin with one containing hydrophobic isodecyl groups, indicating that the immediate environment of the catalytic site affected its performance. The HTB enables fast screening of resins for 3D printing multifunctional architectures with intrinsic catalytic activity, tunable surface properties, and minimal waste. Welcome to talk about 100-51-6, If you have any questions, you can contact Manzano, JS; Wang, H; Slowing, II or send Email.. SDS of cas: 100-51-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C7H6O2. Orlando, G; Ferrante, C; Zengin, G; Sinan, KI; Bene, K; Diuzheva, A; Jeko, J; Cziaky, Z; Di Simone, S; Recinella, L; Chiavaroli, A; Leone, S; Brunetti, L; Picot-Allain, CMN; Mahomoodally, MF; Menghini, L in [Orlando, Giustino; Ferrante, Claudio; Di Simone, Simonetta; Recinella, Lucia; Chiavaroli, Annalisa; Leone, Sheila; Brunetti, Luigi; Menghini, Luigi] Univ G dAnnunzio, Dept Pharm, I-66100 Chieti, Italy; [Zengin, Gokhan; Sinan, Kouadio Ibrahime] Selcuk Univ, Fac Sci, Dept Biol, TR-42130 Konya, Turkey; [Bene, Kouadio] Univ Nangui Abrogoua, Unite Format & Rech Sci Nat, Lab Bot & Phytotherapie, 02 BP 801, Abidjan 02, Cote Ivoire; [Diuzheva, Alina] Czech Univ Life Sci, Fac Forestry & Wood Sci, Dept Forest Protect & Entomol, Prague 16500, Czech Republic; [Jeko, Jozsef; Cziaky, Zoltan] Univ Nyiregyhaza, Agr & Mol Res & Serv Inst, H-4400 Nyiregyhaza, Hungary; [Picot-Allain, Carene Marie Nancy; Mahomoodally, Mohamad Fawzi] Univ Mauritius, Fac Sci, Dept Hlth Sci, Reduit 230, Mauritius published Qualitative Chemical Characterization and Multidirectional Biological Investigation of Leaves and Bark Extracts of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae) in 2019.0, Cited 61.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae) has a long history of use by folk populations for the management of multiple human ailments. Based on the published literature, there has been no attempt to conduct a comparative assessment of the biological activity and the phytochemical profiles of the leaves and stem bark of A. leiocarpus extracted using methanol, ethyl acetate, and water. By high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC-ESI-MSn) analysis, quinic, shikimic, gallic, and protocatechuic acids were tentatively identified from all the extracts, while chlorogenic, caffeic, ferulic, and dodecanedioic acids were only characterised from the leaves extracts. Additionally, a pharmacological study was carried out to evaluate potential protective effects that are induced by the extracts in rat colon and colon cancer HCT116 cell line. In general, the methanol and water extracts of A. leiocarpus leaves and stem bark showed potent radical scavenging and reducing properties. It was noted that the stem bark extracts were more potent antioxidants as compared to the leaves extracts. The methanol extract of A. leiocarpus leaves showed the highest acetyl (4.68 mg galantamine equivalent/g) and butyryl (4.0 mg galantamine equivalent/g) cholinesterase inhibition. Among ethyl acetate extracts, the pharmacological investigation suggested stem bark ethyl acetate extracts to be the most promising. This extract revealed ability to protect rat colon from lipopolysaccharide-induced oxidative stress, without exerting promoting effects on HCT116 cell line viability and migration. As a conclusion, A. leiocarpus represents a potential source of bioactive compounds in the development of novel therapeutic agents.

Computed Properties of C7H6O2. Welcome to talk about 100-83-4, If you have any questions, you can contact Orlando, G; Ferrante, C; Zengin, G; Sinan, KI; Bene, K; Diuzheva, A; Jeko, J; Cziaky, Z; Di Simone, S; Recinella, L; Chiavaroli, A; Leone, S; Brunetti, L; Picot-Allain, CMN; Mahomoodally, MF; Menghini, L or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Dahi-Azar, S; Abdolmohammadi, S; Mokhtari, J in BENTHAM SCIENCE PUBL LTD published article about in [Dahi-Azar, Saman; Mokhtari, Javad] Islamic Azad Univ, Dept Chem, Sci & Res Branch, POB 14515-775, Tehran, Iran; [Abdolmohammadi, Shahrzad] Islamic Azad Univ, Dept Chem, East Tehran Branch, POB 18735-138, Tehran, Iran in 2021, Cited 47. Recommanded Product: 4-Methoxybenzaldehyde. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

Aim and Objective: In the last decades, it has extensively been verified that nanostructured transition metal oxides emerge as inexpensive, available and extremely efficient heterogeneous catalysts in chemical transformations. The high electrical conductivity, high carrier concentration, and improved reactivity in cadmium oxide nanoparticles (CdO NPs) make it as a potential candidate for applications in the fields of nanocatalysis. [1]Benzopyran and pyridopyrimidine derivatives compose major classes of heterocyclic compounds, which have a wide spectrum of biological activities. Materials and Methods: In the present work, we report a facile and highly effective synthesis of 8aryl-8H-[ 1,3]dioxolo[4,5-g][1]benzopyran-6-carboxylic acids and 1,3-dimethyl-2,4-dioxo-5-phenyl-1,2,3,4,5,8-hexahydropyrido[2,3-d] pyrimidine- 7-carboxylic acids via CdO NPs catalyzed cyclo condensation reaction of 4-substituted phenylmethylidenepyruvic acids with 3,4-methylenedioxyphenol or 6-amino-1,3-dimethyluracil, which was accomplished under ethanoldrop grinding at room temperature. The described catalyst was prepared successfully by a simple precipitation method and characterized by the Fourier transformed infrared absorption (FT-IR) spectroscopy, X-Ray diffraction (XRD) analytical technique, and scanning electron microscopy (SEM). Results: A number of [1,3]dioxolo[g][1]benzopyran-6-carboxylic acids and pyrido[d]pyrimidine7-carboxylic acids were effectively synthesized in high yields (96-98%) within short reaction times (10-15 min). All synthesized compounds were well-characterized by IR, H-1 and C-13 NMR spectroscopy, and also by elemental analyses. Conclusion: In summary, we have developed a very simple and impressive procedure for the synthesis of 8-aryl-8H-[1,3]dioxolo[4,5-g][1] benzopyran- 6-carboxylic acids and 1,3-dimethyl-2,4- dioxo-5-phenyl-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidine-7- carboxylic acids as biologically interesting structures in the presence of CdO NPs as an efficient recyclable heterogeneous catalyst. The remarkable advantages for the offered protocol compared with traditional methods are short reaction time, good yields of the products, and the ease of operation with simple work-up procedure.

Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 4-Methoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2020 FOOD ADDIT CONTAM A published article about MASS-SPECTROMETRY; ECHIUM-VULGARE; N-OXIDES; CYNOGLOSSUM-OFFICINALE; VENOOCCLUSIVE DISEASE; METABOLIC-ACTIVATION; MEDICINAL-PLANTS; RISK-ASSESSMENT; IDENTIFICATION; BIOSYNTHESIS in [Maedge, Inga; Gehling, Matthias; Schoene, Cindy; These, Anja] German Fed Inst Risk Assessment, Dept Safety Food Chain, Max Dohrn Str 8-10, D-10589 Berlin, Germany; [Maedge, Inga; Winterhalter, Peter] Tech Univ Carolo Wilhelmina Braunschweig, Inst Food Chem, Braunschweig, Germany in 2020, Cited 64. The Name is (E)-2-Methylbut-2-enoic acid. Through research, I have a further understanding and discovery of 80-59-1. HPLC of Formula: C5H8O2

Pyrrolizidine alkaloids (PAs) and their corresponding N-oxides (PANOs) have been determined in food and feed at levels relevant for consumer health. More than 660 different PAs have been detected, but few are available as reference substances for analytical demands. In the context of the European legislation on maximum levels of PAs in food products, a defined analytical scope of 21 PAs for determination has been suggested. An expansion of the scope from 21 to 35 PAs, including 14 structural isomers, is currently under discussion. In the present study, a target screening method was established for a comprehensive characterisation of PA profiles of the species Echium vulgare, Heliotropium europaeum, Cynoglossum officinale and Symphytum spp. to assess whether an expansion of the analytical scope is required to quantitatively cover the total PA contents of Boraginaceae species. The scope of the method comprised known and unknown PAs previously screened and confirmed in the respective plant extracts. A total of 176 PAs and PANOs were detected. The toxic 1,2-unsaturated PAs represent the predominant PA type with about 98% of the mean total content. This PA profiling demonstrates that an expansion of the scope from 21 to 35 PAs is required to adequately cover the mean total PA contents of Cynoglossum officinale and H. europaeum, whereas in the case of Symphytum spp. and Echium vulgare an expansion would not be necessary.

HPLC of Formula: C5H8O2. Bye, fridends, I hope you can learn more about C5H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Salman, M; Ansari, KR; Srivastava, V; Chauhan, DS; Haque, J; Quraishi, MA in [Salman, Mohammad; Srivastava, Vandana; Haque, Jiyaul] Banaras Hindu Univ, Indian Inst Technol, Dept Chem, Varanasi 221005, Uttar Pradesh, India; [Ansari, K. R.; Chauhan, Dheeraj Singh; Quraishi, M. A.] King Fahd Univ Petr & Minerals, Res Inst, Ctr Res Excellence Corros, Dhahran 31261, Saudi Arabia published Chromeno naphthyridines based heterocyclic compounds as novel acidizing corrosion inhibitors: Experimental, surface and computational study in 2021.0, Cited 65.0. Computed Properties of C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

In the present work three chromeno naphthyridine derivatives (CNs) have been synthesized using one pot multicomponent reaction of 2, 4-hydroxyacetophenone, aromatic aldehydes and malononitrile in water using silica gel as a catalyst. The simulated LDse values for the synthesized compounds are 340 mg/kg (CN-1), 1500 mg/kg (CN-2) and 800 mg/kg (CN-3) which suggest their non-toxic and eco-friendly nature The performance all the three compounds as corrosion inhibitors in 15% HCl on N80 has been analyzed via weight loss, electrochemical, surface characterization, and density functional theory (DFT) methods. Chromeno naphthyridine (CN-1) shows maximum inhibition efficiency of 98.3% at only 300 mg/L The measurement of EIS reveals the process of inhibition of corrosion is governed by control of charge transfer. The mixed nature of CNs adsorption is suggested by results of PDP. Langmuir model of adsorption shows the perfect fitting. Adsorption of CNs onto the metal surface was supported by MR. AFM, and UV-vis. Computational modelling using DFT data reveals that corrosion inhibition takes place by adsorption of both neutral and protonated forms on steel surface. Molecular dynamic simulation (MDS) suggests the parallel adsorption of CNs molecules both in neutral and protonated forms. (C) 2020 Elsevier B.V. All rights reserved.

Welcome to talk about 123-11-5, If you have any questions, you can contact Salman, M; Ansari, KR; Srivastava, V; Chauhan, DS; Haque, J; Quraishi, MA or send Email.. Computed Properties of C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles