Tag: M.W=100-150

Tan, YJ; Ali, A; Tee, SY; Teo, JT; Xi, Y; Go, ML; Lam, YL in [Tan, Yu-Jia; Tee, Sheng-Yang; Lam, Yulin] Natl Univ Singapore, Dept Chem, 3 Sci Dr 3, Singapore 117543, Singapore; [Tan, Yu-Jia; Teo, Jun -Ting] Yong Loo Lin Sch Med, Canc Sci Inst Singapore, 14 Med Dr, Singapore 117599, Singapore; [Xi, Yu; Go, Mei-Lin] Natl Univ Singapore, Dept Pharm, 18 Sci Dr 4, Singapore 117543, Singapore published Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells in 2019.0, Cited 55.0. Quality Control of 3-Hydroxybenzaldehyde. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.

Fatty acid synthase (FASN) is a lipogenic enzyme that is selectively upregulated in malignant cells. There is growing consensus on the oncogenicity of FASN-driven lipogenesis and the potential of FASN as a druggable target in cancer. Here, we report the synthesis and FASN inhibitory activities of two novel galloyl esters of trans-stilbene EC1 and EC5. Inhibition of FASN was accompanied by a loss in AKT activation and profound apoptosis in several non-small cell lung cancer (NSCLC) cells at the growth inhibitory concentrations of EC1 and EC5. Both FASN and phospho-AKT levels were concurrently downregulated. However, addition of a lipid concentrate to the treated cells reinstated cell viability and reversed the loss of FASN and AKT protein levels, thus recapitulating the causal relationship between FASN inhibition and the loss in cell viability. (C) 2019 Elsevier Masson SAS. All rights reserved.

Quality Control of 3-Hydroxybenzaldehyde. Welcome to talk about 100-83-4, If you have any questions, you can contact Tan, YJ; Ali, A; Tee, SY; Teo, JT; Xi, Y; Go, ML; Lam, YL or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of Mequinol. Authors Yabuta, T; Hayashi, M; Matsubara, R in AMER CHEMICAL SOC published article about in [Yabuta, Tatsushi; Hayashi, Masahiko; Matsubara, Ryosuke] Kobe Univ, Grad Sch Sci, Dept Chem, Kobe, Hyogo 6578501, Japan in 2021, Cited 43. The Name is Mequinol. Through research, I have a further understanding and discovery of 150-76-5

Methods to activate the relatively stable ether C-O bonds and convert them to other functional groups are desirable. One-electron reduction of ethers is a potentially promising route to cleave the C-O bond. However, owing to the highly negative redox potential of alkyl aryl ethers (E-red < -2.6 V vs SCE), this mode of ether C-O bond activation is challenging. Herein, we report the visible-light-induced photocatalytic cleavage of the alkyl aryl ether C-O bond using a carbazole-based organic photocatalyst (PC). Both benzylic and non-benzylic aryl ethers underwent C-O bond cleavage to form the corresponding phenol products. Addition of Cs2CO3 was beneficial, especially in reactions using a N-H carbazole PC. The reaction was proposed to occur via single-electron transfer (SET) from the excited-state carbazole to the substrate ether. Interaction of the N-H carbazole PC with Cs2CO3 via hydrogen bonding exists, which enables a deprotonation-assisted electron-transfer mechanism to operate. In addition, the Lewis acidic Cs cation interacts with the substrate alkyl aryl ether to activate it as an electron acceptor. The high reducing ability of the carbazole combined with the beneficial effects of Cs2CO3 made this otherwise formidable SET event possible. Quality Control of Mequinol. Welcome to talk about 150-76-5, If you have any questions, you can contact Yabuta, T; Hayashi, M; Matsubara, R or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2019.0 BIOCHEM SYST ECOL published article about PERFORMANCE LIQUID-CHROMATOGRAPHY; GREEN WALNUT HUSKS; SCLEROTINIA-SCLEROTIORUM LIB; ALNUS-HIRSUTA INHIBIT; CHEMICAL-CONSTITUENTS; ALPHA-TETRALONE; ANTIOXIDANT ACTIVITY; CYTOTOXIC ACTIVITY; PHENOLIC-COMPOUNDS; ESSENTIAL OIL in [Schwindl, Sebastian; Kraus, Birgit; Heilmann, Joerg] Inst Pharmaceut Biol, Univ Str 31, D-93053 Regensburg, Germany in 2019.0, Cited 151.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. SDS of cas: 99-93-4

One new diarylheptanoid (1) and one previously unknown ascorbic acid derivative (2) along with 48 known compounds including three ascorbic acid derivatives (3-5), three diarylheptanoids (6-8), three juglone derivates (9-11), six racemic alpha-tetralones (12a/b-17a/b), four anthraquinones (18-21), eight flavonoids (22-29), nine oligomeric proanthocyanidins (30-38), one phenolic aldehyde (39), one aromatic ketone (40), one pyrrole alkaloid (41), one steroid (42), six terpenes (43-48) and two fatty acids (49-50) were isolated from the leaves of Juglans regia. Their chemical structures were elucidated on basis of 1D and 2D NMR techniques, HRESIMS, polarimetry and CD spectroscopy as well as chiral HPLC and literature data. Furthermore, the chemotaxonomic significance is discussed.

Welcome to talk about 99-93-4, If you have any questions, you can contact Schwindl, S; Kraus, B; Heilmann, J or send Email.. SDS of cas: 99-93-4

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Acetylacetone as an oxygen activator to improve efficiency for aerobic oxidation of toluene and its derivatives by using cobaltmeso-tetraphenylporphyrin WOS:000544759800011 published article about LIQUID-PHASE OXIDATION; FREE SELECTIVE OXIDATION; SOLVENT-FREE OXIDATION; H BOND ACTIVATION; CATALYTIC-OXIDATION; SPECTROSCOPIC CHARACTERIZATION; MOLECULAR-OXYGEN; SURFACE; MANGANESE; COMPLEX in [Zhou, Xian-Tai; Han, Qi] Sun Yat Sen Univ, Sch Chem Engn & Technol, Zhuhai 519082, Peoples R China; [Chen, Hong-Yu; Lv, Meng; Ji, Hong-Bing] Sun Yat Sen Univ, Sch Chem, Fine Chem Ind Res Inst, Guangzhou 510275, Guangdong, Peoples R China; [Ji, Hong-Bing] Guangdong Univ Petrochem Technol, Sch Chem Engn, Maoming 525000, Peoples R China in 2020, Cited 43. Recommanded Product: 100-51-6. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

The activation of dioxygen is the major challenge in the catalytic oxygenation of hydrocarbons under mild conditions. In this study, the catalytic efficiency for the aerobic oxidation of toluene and its derivatives by using cobaltmeso-tetraphenylporphyrin was enhanced by using acetylacetone as the oxygen activator. The influences of reaction conditions such as solvent, different metalloporphyrin catalysts, temperature, pressure and acetylacetone loading were studied, as well as the kinetics of the oxidation. Various toluene derivatives could also be oxidized to the corresponding products in satisfactory yields with this catalytic system. Based on the characterization ofin situelectron paramagnetic resonance (EPR) andin situUV-vis spectroscopy, the catalytic mechanism was also proposed, in which acetylacetone served as the key initiator of the free radical in activating dioxygen.

Recommanded Product: 100-51-6. Welcome to talk about 100-51-6, If you have any questions, you can contact Zhou, XT; Chen, HY; Han, Q; Lv, M; Ji, HB or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C8H8O2. In 2021.0 TETRAHEDRON LETT published article about BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; MOLECULAR DOCKING; POTENTIAL HIV-1; INHIBITORS; DESIGN; MODELS in [Boureghda, Chaima; Boulcina, Raouf; Debache, Abdelmadjid] Univ Freres Mentouri Constantine 1, Lab Synth Mol Interets Biol, Constantine 25000, Algeria; [Dorcet, Vincent; Berree, Fabienne; Carboni, Bertrand] Univ Rennes, CNRS, ISCR Inst Sci Chim Rennes, UMR 6226, F-35000 Rennes, France in 2021.0, Cited 55.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

A simple, efficient and environment-friendly procedure for the synthesis of 5-arylidene rhodanines derivatives via a Knoevenagel type reaction was developed using rhodanine, a variety of differently substituted aldehydes and Na2SO3 as benign catalyst in ethanol. Selected 5-arylidene rhodanines were subjected to basic hydrolysis to afford 2-mercapto-3-substituted-acrylic acids. The presence of a boronic acid group is well tolerated in such transformations. In the case of 2-formylphenylboronic acid, this sequence opens access to a new benzoxaborole derivative. (C) 2020 Elsevier Ltd. All rights reserved.

HPLC of Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Ye, JH; Bellotti, P; Paulisch, TO; Daniliuc, CG; Glorius, F in WILEY-V C H VERLAG GMBH published article about in [Ye, Jian-Heng; Bellotti, Peter; Paulisch, Tiffany O.; Daniliuc, Constantin G.; Glorius, Frank] Westfalische Wilhelms Univ Munster, Organ Chem Inst, Corrensstr 40, D-48149 Munster, Germany in 2021.0, Cited 61.0. HPLC of Formula: C8H8O2. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5

We report the synthesis of beta-lactams from alpha-ketoacylsilanes and imines, which proceeds via a formal [2+2] photochemical cycloaddition with in situ generation of siloxyketene. This mild and operationally simple reaction proceeds in an atom-economic fashion with broad substrate scope, including aldimines, ketimines, hydrazones, and fused nitrogen heterocycles, affording a variety of important beta-lactams with satisfactory diastereoselectivities in most cases. This reaction also features good functional-group tolerance, facile scalability and product diversification. Experimental and computational studies suggest that alpha-ketoacylsilanes can serve as photochemical precursors by engaging in a 1,3 silicon shift to the distal carbonyl group.

Welcome to talk about 123-11-5, If you have any questions, you can contact Ye, JH; Bellotti, P; Paulisch, TO; Daniliuc, CG; Glorius, F or send Email.. HPLC of Formula: C8H8O2

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 100-83-4. Authors Tereshko, AB; Kozlov, NG in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Tereshko, A. B.; Kozlov, N. G.] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk, BELARUS in 2019.0, Cited 13.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4

New 7-aryl(hetaryl)-9,10-dihydro-7H-cyclopenta[b][1,7]phenanthrolin-8(11H)-ones have been synthesized by three-component condensation of quinolin-5-amine with cyclopentane-1,3-dione and aldehydes of the aromatic and heteroaromatic series.

Recommanded Product: 100-83-4. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Tereshko, AB; Kozlov, NG or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

I found the field of Chemistry very interesting. Saw the article Reaction of enamines with semicarbazone-based amidoalkylating reagents: A straightforward synthesis of annulated 1-aminopyrimidin-2-one derivatives published in 2021.0. Quality Control of 4-Methoxybenzaldehyde, Reprint Addresses Shutalev, AD (corresponding author), Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Ave, Moscow 119991, Russia.. The CAS is 123-11-5. Through research, I have a further understanding and discovery of 4-Methoxybenzaldehyde

An efficient synthesis of 1-arylideneamino-substituted hexahydro-1H-cyclopenta[d]pyrimidin-2-ones and octahydroquinazolin-2-ones has been developed. The synthesis involves a stereo- and regioselective cascade reaction of the corresponding 4-(tosylmethyl)semicarbazones with 1-morpholinocyclopentene or 1-morpholinocyclohexene to give predominantly bicyclic pyrimidines with an exocyclic C=C double bond (80-97%). The later undergo rapid isomerization when heated in THF in the presence of TsOH to form bicyclic pyrimidines with a significant predominance of those with an endocyclic C=C double bond (90-97%). (C) 2021 Elsevier Ltd. All rights reserved.

Quality Control of 4-Methoxybenzaldehyde. Welcome to talk about 123-11-5, If you have any questions, you can contact Fesenko, AA; Shutalev, AD or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 123-11-5. Kiyokawa, K; Urashima, N; Minakata, S in [Kiyokawa, Kensuke; Urashima, Naruyo; Minakata, Satoshi] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Osaka 5650871, Japan published Tris(pentafluorophenyl)borane-Catalyzed Formal Cyanoalkylation of Indoles with Cyanohydrins in 2021, Cited 64. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5.

Despite the significant achievements related to the C3 functionalization of indoles, cyanoalkylation reactions continue to remain rather limited. We herein report on the formal C3 cyanoalkylation of indoles with cyanohydrins in the presence of a tris(pentafluorophenyl)borane (B(C6F5)(3)) catalyst. It is noteworthy that cyanohydrins are used as a cyanoalkylating reagent in the present reaction, even though they are usually used as only a HCN source. Mechanistic investigations revealed the unique reactivity of the B(C6F5)(3) catalyst in promoting the decomposition of a cyanohydrin by a Lewis acidic activation through the coordination of the cyano group to the boron center. In addition, a catalytic three-component reaction using indoles, aldehydes as a carbon unit, and acetone cyanohydrin that avoids the discrete preparation of each aldehyde-derived cyanohydrin is also reported. The developed methods provide straightforward, highly efficient, and atom-economic access to various types of synthetically useful indole-3-acetonitrile derivatives containing alpha-tertiary or quaternary carbon centers.

Welcome to talk about 123-11-5, If you have any questions, you can contact Kiyokawa, K; Urashima, N; Minakata, S or send Email.. SDS of cas: 123-11-5

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Liang, YY; Zhao, XD in [Zhao, Xiaodan] Sun Yat Sen Univ, Inst Organ Chem, Sch Chem, Guangzhou 510275, Guangdong, Peoples R China; Sun Yat Sen Univ, MOE Key Lab Bioinorgan & Synthet Chem, Sch Chem, Guangzhou 510275, Guangdong, Peoples R China published Enantioselective Construction of Chiral Sulfides via Catalytic Electrophilic Azidothiolation and Oxythiolation of N-Allyl Sulfonamides in 2019.0, Cited 69.0. Name: Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

An efficient and convenient pathway was developed for enantioselective synthesis of chiral sulfides by chiral bifunctional selenide-catalyzed electrophilic azidothio-lation and oxythiolation of N-allyl sulfonamides. By this protocol, a variety of chiral vicinal azidosulfides and oxysulfides were obtained in good yields with high enantioselectivities and diastereoselectivities. In this transformation, not only electrophilic arylthiolating reagents but also a wide range of electrophilic alkylthiolating reagents worked very well. The practical application of this method was elucidated by further transformations of the products into the diversified compounds.

Name: Benzyl Alcohol. Welcome to talk about 100-51-6, If you have any questions, you can contact Liang, YY; Zhao, XD or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles