The important role of 132098-59-0

There is still a lot of research devoted to this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Category: indole-building-block, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Organic Chemistry called Enantiopure Fluorous Bis(oxazolines): Synthesis and Applications in Catalytic Asymmetric Reactions, Author is Bayardon, Jerome; Sinou, Denis, which mentions a compound: 132098-59-0, SMILESS is C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1, Molecular C19H18N2O2, Category: indole-building-block.

Various enantiopure fluorous bis(oxazolines) with fluorine content between 52.7 and 58.7% have been synthesized by a simple reaction sequence that involved the introduction of two fluorinated ponytails by alkylation of the corresponding nonfluorous bis(oxazolines). For example, the 2,2′-[1-(heptadecafluoroundecyl)dodecylidene]bis[4,5-dihydro-4-(1-methylethyl)-4-oxazolemethanol] (I) was prepared in several steps. These new ligands have been used in palladium-catalyzed alkylation of α-[(1E)-2-phenylethenyl]benzenemethanol acetate with carbon nucleophiles and in copper-catalyzed oxidation of cycloalkenes. The stereoselective allylic alkylation of α-[(1E)-2-phenylethenyl]benzenemethanol acetate with propanedioic acid di-Me ester gave [(1R,2E)-1,3-diphenyl-2-propenyl]propanedioic acid di-Me ester in 89% enantiomeric excess. These ligands exhibited enantioselectivities up to 98 and 77%, resp., quite close to the values obtained using the analogous nonfluorous bis(oxazolines). These ligands could be easily recovered by liquid-liquid extraction or solid-liquid separation and reused with the same enantioselectivities.

There is still a lot of research devoted to this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Category: indole-building-block, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles