Recently I am researching about STREPTOCOCCUS-MUTANS; INSPIRED ANALOGS; DENTAL-CARIES; MAGNOLOL; BIOFILM, Saw an article supported by the NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [GM112684, GM131902, DE025837, T32 GM071339]; NSFNational Science Foundation (NSF) [1S10RR023444, 1S10RR022442, CHE 0840438, CHE-0848460, 1S10OD011980, CHE1764298, CHE1755698]; Emory University Integrated Cellular Imaging Microscopy Core. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Ochoa, C; Solinski, AE; Nowlan, M; Dekarske, MM; Wuest, WM; Kozlowski, MC. The CAS is 100-83-4. Through research, I have a further understanding and discovery of 3-Hydroxybenzaldehyde. Recommanded Product: 100-83-4
Targeting Streptococcus mutans is the primary focus in reducing dental caries, one of the most common maladies in the world. Previously, our groups discovered a potent bactericidal biaryl compound that was inspired by the natural product honokiol. Herein, a structure activity relationship (SAR) study to ascertain structural motifs key to inhibition is outlined. Furthermore, mechanism studies show that bacterial membrane disruption is central to the bacterial growth inhibition. During this process, it was discovered that analog C2 demonstrated a 4-fold better therapeutic index compared to the commercially available antimicrobial cetylpyridinium chloride (CPC) making it a viable alternative for oral care.
Welcome to talk about 100-83-4, If you have any questions, you can contact Ochoa, C; Solinski, AE; Nowlan, M; Dekarske, MM; Wuest, WM; Kozlowski, MC or send Email.. Recommanded Product: 100-83-4
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles