On June 30, 2008, Vesely, Jan; Zhao, Gui-Ling; Bartoszewicz, Agnieszka; Cordova, Armando published an article.Category: indole-building-block The title of the article was Organocatalytic asymmetric nitrocyclopropanation of α,β-unsaturated aldehydes. And the article contained the following:
A novel organocatalytic, highly enantioselective nitrocyclopropanation of α,β-unsaturated aldehydes is presented. The 1-nitro-2-formylcyclopropane derivatives synthesized from this catalytic transformation were converted to the corresponding β-nitromethyl-acid esters, which are excellent precursors of GABA analogs such as baclofen, by subsequent organocatalytic, chemoselective ring-opening. The experimental process involved the reaction of H-Idc-OH(cas: 79815-20-6).Category: indole-building-block
The Article related to unsaturated aldehyde bromonitromethane stereoselective nitrocyclopropanation organocatalyst, nitrocyclopropanecarboxaldehyde stereoselective preparation ring opening, nitro ester baclofen precursor stereoselective preparation, gaba analog precursor nitro ester stereoselective preparation and other aspects.Category: indole-building-block
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles