Wang, Cong-Shuai published the artcileDesign of C3-Alkenyl-Substituted 2-Indolylmethanols for Catalytic Asymmetric Interrupted Nazarov-Type Cyclization, HPLC of Formula: 100123-25-9, the publication is Advanced Synthesis & Catalysis (2018), 360(5), 846-851, database is CAplus.
The C3-alkenyl-substituted 2-indolylmethanols were designed as a new class of substrates for catalytic asym. interrupted Nazarov-type cyclizations. In the presence of a chiral phosphoric acid as a mild chiral Bronsted acid, the interrupted Nazarov-type cyclization of C3-alkenyl-substituted 2-indolylmethanols I (R1 = Ph, 4-ClC6H4, 2-FC6H4, etc.; R2 = Ph, 3-FC6H4, 3-MeC6H4; R3 = H, Cl, Br, MeO) with nucleophiles R4H (R4 = 3-indolyl, 2-hydroxy-1-naphthyl, etc.) occurred smoothly to construct cyclopenta[b]indole frameworks II with generally excellent diastereo- and enantioselectivities (up to >95:5 dr, >99% ee).
Advanced Synthesis & Catalysis published new progress about 100123-25-9. 100123-25-9 belongs to indole-building-block, auxiliary class Indole,Bromide,Ester,Aldehyde, name is Ethyl 5-bromo-3-formyl-1H-indole-2-carboxylate, and the molecular formula is C6H5F4NO3S, HPLC of Formula: 100123-25-9.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles