I found the field of Materials Science very interesting. Saw the article Amphiphilic phthalocyanines in polymeric micelles: a supramolecular approach toward efficient third-generation photosensitizers published in 2020.0. Recommanded Product: 100-51-6, Reprint Addresses de la Escosura, A; Torres, T (corresponding author), Univ Autonoma Madrid, Organ Chem Dept, E-28049 Madrid, Spain.; van Nostrum, CF (corresponding author), Univ Utrecht, UIPS, Dept Pharmaceut, NL-3508 TB Utrecht, Netherlands.; de la Escosura, A; Torres, T (corresponding author), Inst Adv Res Chem Sci IAdChem, Madrid 28049, Spain.; Torres, T (corresponding author), IMDEA Nanasience, Ciudad Univ Cantoblanco, Madrid 28049, Spain.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol
In this paper we describe a straightforward supramolecular strategy to encapsulate silicon phthalocyanine (SiPc) photosensitizers (PS) in polymeric micelles made of poly(epsilon-caprolactone)-b-methoxypoly(ethylene glycol) (PCL-PEG) block copolymers. While PCL-PEG micelles are promising nanocarriers based on their biocompatibility and biodegradability, the design of our new PS favors their encapsulation. In particular, they combine two axial benzoyl substituents, each of them carrying either three hydrophilic methoxy(triethylenoxy) chains (1), three hydrophobic dodecyloxy chains (3), or both kinds of chains (2). The SiPc derivatives 1 and 2 are therefore amphiphilic, with the SiPc unit contributing to the hydrophobic core, while lipophilicity increases along the series, making it possible to correlate the loading efficacy in PCL-PEG micelles with the hydrophobic/hydrophilic balance of the PS structure. This has led to a new kind of third-generation nano-PS that efficiently photogenerates O-1(2), while preliminary in vitro experiments demonstrate an excellent cellular uptake and a promising PDT activity.
Recommanded Product: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Setaro, F; Wennink, JWH; Makinen, PI; Holappa, L; Trohopoulos, PN; Yla-Herttuala, S; van Nostrum, CF; de la Escosura, A; Torres, T or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles