Recently I am researching about DIRECT ORTHO ARYLATION; CARBOXYLIC-ACIDS; BENZOIC-ACIDS; BOND; PALLADIUM; HYDROARYLATION; OLEFINATION; ARYL; ALKYNES; ACTIVATION, Saw an article supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence StrategyGerman Research Foundation (DFG) [EXC-2033-390677874]; BMBFFederal Ministry of Education & Research (BMBF); state of NRW (Center of Solvation Science ZEMOS); CSC; [SFB-TRR88]; [GO 853/12-1]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Hu, ZY; Belitz, F; Zhang, GD; Papp, F; Goossen, LJ. The CAS is 80-59-1. Through research, I have a further understanding and discovery of (E)-2-Methylbut-2-enoic acid. Recommanded Product: 80-59-1
In the presence of [p-cymene)RuCl2](2), (E)-configured alkenyl bromides couple with aromatic carboxylates to form orthovinylbenzoic acids. This C-H vinylation proceeds in high yields without any activating phosphine ligands and has an excellent functional group tolerance. Starting from commonly available (E/Z)-mixtures of alkenyl bromides, (E)-configured vinyl arenes or dienes are formed exclusively. Mechanistic studies show that this selectivity is achieved because the (E)configured alkenyl bromides undergo a smooth coupling, whereas the (Z)-isomers are rapidly eliminated with the formation of alkynes.
Welcome to talk about 80-59-1, If you have any questions, you can contact Hu, ZY; Belitz, F; Zhang, GD; Papp, F; Goossen, LJ or send Email.. Recommanded Product: 80-59-1
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles