Formula: C9H10O3. In 2021.0 CHEM NAT COMPD+ published article about XANTHOHUMOL in [Su, Liang; Liu, Ke-Xiong; Han, Pei-Pei; Wang, Qiu-An] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China in 2021.0, Cited 16.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.
Prenylated chalcones xanthohumol (1) and 2 ‘-hydroxy-3,4,4 ‘-trimethoxy-6 ‘-O-prenyl chalcone (2) were synthesized through the Claisen-Schmidt condensation, O-prenylation, and Claisen rearrangement and deprotection respectively, using phloroglucinol and appropriate benzaldehydes as starting materials. Based on the Mannich reaction of prenylated chalcone 1 or 2 with various secondary amines and formaldehyde in acid alcohol solvent, 10 novel prenylated chalcone Mannich base derivatives 3a-3e and 4a-4e were synthesized. Furthermore, all synthetic compounds were evaluated for antiproliferative activities in vitro against four human cancer cell lines (Aspc-1, SUN-5, HepG-2, and HCT-116) by MTT assay. The results showed that most of them exhibit moderate to good antiproliferative activities against the four human cancer cells with IC50 values of 2.52 to 47.67 mu M.
Formula: C9H10O3. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles