Recommanded Product: 99-93-4. Chen, Y; Li, P; Chen, M; He, J; Su, SJ; He, M; Wang, H; Xue, W in [Chen, Ying; Li, Pu; Chen, Mei; He, Jun; Su, Shijun; He, Ming; Xue, Wei] Guizhou Univ, Ctr Res & Dev Fine Chem, State Key Lab Breeding Base Green Pesticide & Agr, Guiyang 550025, Peoples R China; [Wang, Hua] Hubei Acad Agr Sci, Inst Plant Protect & Soil Sci, Wuhan 430064, Peoples R China published Synthesis and antibacterial activity of chalcone derivatives containing thioether triazole in 2020.0, Cited 36.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.
The infection of Xanthomonas oryzae pv. Oryzae (Xoo), Ralstonia solanacearum (Rs), and Xanthomonas axonopodis pv. Citri (Xac) has become a major problem in agricultural production. In this study, a series of novel chalcone derivatives containing thioether triazoles were designed and synthesized. The structures of the novel compounds were systematically characterized via H-1-NMR, C-13-NMR, and HRMS. Moreover, the antibacterial activity results showed that E-10, E-11, E-15, and E-16 have adequate antibacterial activities against Xoo, Rs, and Xac. Among the different compounds, E-15 exhibited remarkable inhibitory effect against Xac with an EC50 of 9.1 mu g.mL(-1), which was better than that of commercial agent bismerthiazol (54.9 mu g.mL(-1)). In addition, the possible antibacterial mechanism of the target compound E-15 against Xac was studied via scanning electron microscopy (SEM).
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles