An article Unusual C-O bond cleavage of aromatic ethers in ruthenium complexes bearing a 2-alkoxypyridyl fragment WOS:000486226200009 published article about METAL-LIGAND COOPERATION; DEHYDROGENATIVE OXIDATION; TRANSFER HYDROGENATION; SECONDARY ALCOHOLS; IRIDIUM COMPLEXES; BIPYRIDONATE LIGAND; ACTIVE CATALYSTS; ALPHA-ALKYLATION; BETA-ALKYLATION; KETONES in [Deng, Danfeng; Hu, Bowen; Yang, Min; Chen, Dafa] Harbin Inst Technol, Sch Chem Engn & Technol, MIIT Key Lab Crit Mat Technol New Energy Convers, Harbin 150001, Heilongjiang, Peoples R China in 2019.0, Cited 38.0. Application In Synthesis of Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
Two tetradentate (NNOP) ruthenium products [{RO-C5H3N-C5H3N-CH(O)-C6H4-PPh2}Ru(CO)(PPh3)]Cl (1: R = Me; 3: R = Ph) were isolated by the reactions of the corresponding ligands with RuHCl(PPh3)(3)(CO). Complex 1 could also be transformed into 2 when heated in THF, through C-OMe bond cleavage. The mechanism of the unusual C-O cleavage in complex 1 was investigated, and the results indicate that it is an S(N)2 mechanism through the attack of trace amounts of neutral H2O. In contrast, in the presence of KOH, the reaction switches to an SNAr chemistry. The bidentate ruthenium isomers [{CH3O-C5H3N-C5H4N}RuH(CO)(PPh3)(2)]Cl (4a and 4b) could undergo similar C-O cleavage, affording product {O-C5H3N-C5H4N}RuH(CO)(PPh3)(2) (5), which reacted with HCl to generate complex [{HO-C5H3N-C5H4N}RuH(CO)(PPh3)(2)]Cl (6). These complexes were tested as catalysts for beta-alkylation of secondary alcohols with primary alcohols, and a series of beta-alkylated 1-phenylethanol derivatives were isolated in high yields.
Application In Synthesis of Benzyl Alcohol. Bye, fridends, I hope you can learn more about C7H8O, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles